scholarly journals The role of fibroblasts and fibroblast-derived factors in periprosthetic osteolysis

2006 ◽  
Vol 54 (10) ◽  
pp. 3221-3232 ◽  
Author(s):  
Tamas Koreny ◽  
Miklós Tunyogi-Csapó ◽  
Istvan Gál ◽  
Csaba Vermes ◽  
Joshua J. Jacobs ◽  
...  
Keyword(s):  
Periprosthetic Osteolysis

The role of implant alignment on stability and particles on periprosthetic osteolysis?A rabbit model of implant failure

2004 ◽  
Vol 70B (2) ◽  
pp. 179-186 ◽  
Author(s):  
V. L. Fornasier ◽  
S. B. Goodman ◽  
K. Protzner ◽  
M. Kamel ◽  
Y. Song ◽  
...  
Keyword(s):  
Rabbit Model ◽  
Implant Failure ◽  
Periprosthetic Osteolysis ◽  
Implant Alignment

The potential role of fibroblasts in periprosthetic osteolysis: Fibroblast response to titanium particles

2009 ◽  
Vol 10 (9) ◽  
pp. 1417-1427 ◽  
Author(s):  
Jianling Yao ◽  
Tibor T. Glant ◽  
Michael W. Lark ◽  
Katalin Mikecz ◽  
Joshua J. Jacobs ◽  
...  
Keyword(s):  
Potential Role ◽  
Periprosthetic Osteolysis

Role of Particulate Debris in Periprosthetic Osteolysis

1993 ◽  
Vol 8 (4) ◽  
pp. 245-253 ◽  
Author(s):  
Jeng-Tzung Wang ◽  
Yoshitada Harada ◽  
Vivek A. Doppalapudi ◽  
Steven R. Goldring
Keyword(s):  
Periprosthetic Osteolysis ◽  
Particulate Debris

scholarly journals Orthopaedic implant failure: aseptic implant loosening–the contribution and future challenges of mouse models in translational research

2014 ◽  
Vol 127 (5) ◽  
pp. 277-293 ◽  
Author(s):  
Luis Alberto Cordova ◽  
Verena Stresing ◽  
Bérengère Gobin ◽  
Philippe Rosset ◽  
Norbert Passuti ◽  
...  
Keyword(s):  
Aseptic Loosening ◽  
Mouse Models ◽  
Implant Failure ◽  
Orthopaedic Implant ◽  
Implant Loosening ◽  
Periprosthetic Osteolysis ◽  
New Era ◽  
Future Challenges

Aseptic loosening as a result of wear debris is considered to be the main cause of long-term implant failure in orthopaedic surgery and improved biomaterials for bearing surfaces decreases significantly the release of micrometric wear particles. Increasingly, in-depth knowledge of osteoimmunology highlights the role of nanoparticles and ions released from some of these new bearing couples, opening up a new era in the comprehension of aseptic loosening. Mouse models have been essential in the progress made in the early comprehension of pathophysiology and in testing new therapeutic agents for particle-induced osteolysis. However, despite this encouraging progress, there is still no valid clinical alternative to revision surgery. The present review provides an update of the most commonly used bearing couples, the current concepts regarding particle–cell interactions and the approaches used to study the biology of periprosthetic osteolysis. It also discusses the contribution and future challenges of mouse models for successful translation of the preclinical progress into clinical applications.

scholarly journals The Central Role of Wear Debris in Periprosthetic Osteolysis

2006 ◽  
Vol 2 (2) ◽  
pp. 102-113 ◽  
Author(s):  
P. Edward Purdue ◽  
Panagiotis Koulouvaris ◽  
Bryan J. Nestor ◽  
Thomas P. Sculco
Keyword(s):  
Wear Debris ◽  
Periprosthetic Osteolysis

Role of dactinomycin in the improved survival of children with Wilms' tumor

JAMA ◽  
1966 ◽  
Vol 195 (12) ◽  
pp. 1005-1009 ◽  
Author(s):  
D. J. Fernbach
Keyword(s):  
Wilms Tumor

Role of the allergist in diagnosis and management of patients with uveitis

JAMA ◽  
1966 ◽  
Vol 195 (3) ◽  
pp. 167-172 ◽  
Author(s):  
T. E. Van Metre
Keyword(s):  
Diagnosis And Management
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