Increased levels of transforming growth factor β receptor type I and up-regulation of matrix gene program: A model of scleroderma

2006 ◽  
Vol 54 (9) ◽  
pp. 3011-3021 ◽  
Author(s):  
Jaspreet Pannu ◽  
Humphrey Gardner ◽  
Jeffrey R. Shearstone ◽  
Edwin Smith ◽  
Maria Trojanowska
Keyword(s):  
Growth Factor ◽  
Transforming Growth Factor ◽  
Transforming Growth Factor Β ◽  
Receptor Type ◽  
Type I ◽  
Matrix Gene ◽  
Β Receptor

scholarly journals Transforming Growth Factor-β Receptor Type I-dependent Fibrogenic Gene Program Is Mediated via Activation of Smad1 and ERK1/2 Pathways

2007 ◽  
Vol 282 (14) ◽  
pp. 10405-10413 ◽  
Author(s):  
Jaspreet Pannu ◽  
Sashidhar Nakerakanti ◽  
Edwin Smith ◽  
Peter ten Dijke ◽  
Maria Trojanowska
Keyword(s):  
Growth Factor ◽  
Transforming Growth Factor ◽  
Transforming Growth Factor Β ◽  
Receptor Type ◽  
Type I ◽  
Β Receptor

scholarly journals Repression of transforming growth factor-β receptor type I promoter expression by Sp1 deficiency

Oncogene ◽  
2000 ◽  
Vol 19 (40) ◽  
pp. 4660-4667 ◽  
Author(s):  
Sumudra Periyasamy ◽  
Sudhakar Ammanamanchi ◽  
Manoranjani PM Tillekeratne ◽  
Michael G Brattain
Keyword(s):  
Growth Factor ◽  
Transforming Growth Factor ◽  
Transforming Growth Factor Β ◽  
Receptor Type ◽  
Type I ◽  
Β Receptor

scholarly journals Preclinical assessment of galunisertib (LY2157299 monohydrate), a first-in-class transforming growth factor-β receptor type I inhibitor

Oncotarget ◽  
2017 ◽  
Vol 9 (6) ◽  
pp. 6659-6677 ◽  
Author(s):  
Jonathan M. Yingling ◽  
William T. McMillen ◽  
Lei Yan ◽  
Huocong Huang ◽  
J. Scott Sawyer ◽  
...  
Keyword(s):  
Growth Factor ◽  
Transforming Growth Factor ◽  
Transforming Growth Factor Β ◽  
Receptor Type ◽  
Type I ◽  
Β Receptor

scholarly journals Int7G24A Variant of Transforming Growth Factor-β Receptor Type I Is Associated with Invasive Breast Cancer

2006 ◽  
Vol 12 (2) ◽  
pp. 392-397 ◽  
Author(s):  
Taiping Chen ◽  
Chad R. Jackson ◽  
Andrew Link ◽  
Michael P. Markey ◽  
Bruce M. Colligan ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Growth Factor ◽  
Invasive Breast Cancer ◽  
Transforming Growth Factor ◽  
Transforming Growth Factor Β ◽  
Receptor Type ◽  
Type I ◽  
Β Receptor
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