Short-term corticosteroids then lamivudine and plasma exchanges to treat hepatitis B virus-related polyarteritis nodosa

2004 ◽  
Vol 51 (3) ◽  
pp. 482-487 ◽  
Author(s):  
L. Guillevin ◽  
A. Mahr ◽  
P. Cohen ◽  
C. Larroche ◽  
V. Queyrel ◽  
...  
Keyword(s):  
Hepatitis B Virus ◽  
Hepatitis B ◽  
Polyarteritis Nodosa ◽  
Short Term ◽  
B Virus

Successful treatment of hepatitis B virus associated polyarteritis nodosa with a combination of prednisolone, alpha-interferon and lamivudine

2000 ◽  
Vol 33 (4) ◽  
pp. 677-683 ◽  
Author(s):  
Andreas Erhardt ◽  
Abdurrahman Sagir ◽  
Loic Guillevin ◽  
Eva Neuen-Jacob ◽  
Dieter Haussinger
Keyword(s):  
Hepatitis B Virus ◽  
Hepatitis B ◽  
Successful Treatment ◽  
Polyarteritis Nodosa ◽  
Alpha Interferon ◽  
B Virus

Polyarteritis Nodosa Following Vaccination Against Hepatitis B Virus with Lower-Extremity Manifestations: A Case Report

2019 ◽  
Vol 109 (3) ◽  
pp. 241-245
Author(s):  
Daniel R. Wright ◽  
Jenni M. Davis ◽  
Karl Robstad ◽  
Melissa D. Shah ◽  
Michael C. Keller ◽  
...  
Keyword(s):  
Case Report ◽  
Hepatitis B Virus ◽  
Virus Infection ◽  
Hepatitis B ◽  
Polyarteritis Nodosa ◽  
Peripheral Nerves ◽  
Hepatitis B Virus Infection ◽  
Multiple Organs ◽  
B Virus ◽  
Life Threatening

Polyarteritis nodosa is a progressive, often life-threatening, vasculitis affecting multiple organs, including the skin and peripheral nerves. We report a patient presenting with systemic features of the disease and with characteristic lesions in the feet 3 weeks after vaccination against hepatitis B virus infection.

scholarly journals Serum Clusterin: A Potential Marker for Assessing the Clinical Severity and Short-Term Prognosis of Hepatitis B Virus-Related Acute-on-Chronic Liver Failure

2020 ◽  
Vol 2020 ◽  
pp. 1-11
Author(s):  
Huimin Liu ◽  
Yuxin Li ◽  
Fangyuan Gao ◽  
Peipei Meng ◽  
Hao Yu ◽  
...  
Keyword(s):  
Hepatitis B Virus ◽  
Hepatitis B ◽  
Liver Failure ◽  
Chronic Liver ◽  
Clinical Severity ◽  
Chronic Liver Failure ◽  
Short Term ◽  
Potential Biomarker ◽  
B Virus ◽  
Normal Controls

Background. Acute-on-chronic liver failure (ACLF) is a clinical syndrome characterized by acute deterioration of liver function and high short-term mortality. Clusterin, with biological functions similar to small heat shock proteins, can protect cells from apoptosis induced by various stressors. The aim of this study was to detect the level of serum clusterin in hepatitis B virus- (HBV-) related ACLF and to assess the predictive value of clusterin for the short-term prognosis of HBV-ACLF. Methods. We detected serum clusterin by ELISA in 108 HBV-ACLF patients, 63 HBV-non-ACLF patients, and 44 normal controls. Results. Serum clusterin was markedly lower in HBV-ACLF patients (median, 51.09 μg/mL) than in HBV-non-ACLF patients (median, 188.56 μg/mL) and normal controls (median, 213.45 μg/mL; all P < 0.05 ). Nonsurviving HBV-ACLF patients who died within 90 days had much lower clusterin levels than did surviving patients, especially those who died within 28 days (nonsurvival group vs. survival group: 39.82 ± 19.34 vs. 72.26 ± 43.52 , P < 0.001 ; survival time ≤ 28 vs. survival time > 28 : median 28.39 vs. 43.22, P = 0.013 ). The results showed that for identifying HBV-ACLF, the sensitivity of clusterin (93.7%) was similar to the sensitivities of the international normalized ratio (INR; 94.4%) and total bilirubin (TBIL; 94.8%), but its specificity (90.7%) was higher than that of prothrombin activity (PTA; 65.8%) and TBIL (69.8%) and was similar to INR (88.9%). As the concentration of clusterin increased, the mortality of HBV-ACLF patients decreased significantly from 59.3% to 7.0%. Clusterin had better ability for predicting the prognosis of HBV-ACLF patients than did the model for end-stage liver disease (MELD) score and the chronic liver failure consortium (CLIF-C) ACLF score (MELD vs. clusterin: P = 0.012 ; CLIF-C ACLF vs. clusterin: P = 0.031 ). Conclusion. Serum clusterin is a potential biomarker for HBV-ACLF which can be used to assess clinical severity and the short-term prognosis of patients with this disease and may help clinicians identify HBV-ACLF with greater specificity and improved prognostic accuracy than existing prognostic markers.

Treatment of hepatitis B virus-related polyarteritis nodosa: two case reports and a review of the literature

2004 ◽  
Vol 23 (2) ◽  
pp. 172-176 ◽  
Author(s):  
D. H. Deeren ◽  
A. I. De Backer ◽  
M. L. N. G. Malbrain ◽  
H. Verbraeken ◽  
D. Blockmans
Keyword(s):  
Hepatitis B Virus ◽  
Hepatitis B ◽  
Polyarteritis Nodosa ◽  
Case Reports ◽  
Review Of The Literature ◽  
B Virus

Polyarteritis Nodosa Associated With Gastric Carcinoma and Hepatitis B Virus Infection

1997 ◽  
Vol 25 (3) ◽  
pp. 535-537 ◽  
Author(s):  
Toshio Yamada ◽  
Hiroto Miwa ◽  
Keigo Ikeda ◽  
Kazuki Ohta ◽  
Ryozo Iwazaki ◽  
...  
Keyword(s):  
Hepatitis B Virus ◽  
Virus Infection ◽  
Hepatitis B ◽  
Gastric Carcinoma ◽  
Polyarteritis Nodosa ◽  
Hepatitis B Virus Infection ◽  
B Virus
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