Low-dose methotrexate with leucovorin (folinic acid) in the management of rheumatoid arthritis. results of a multicenter randomized, double-blind, placebo-controlled trial

Jeffrey B. Shiroky; Carolyn Neville; John M. Esdaile; Denis Choquette; Michel Zummer; Mark Hazeltine; Vivian Bykerk; Mohamed Kanji; Anne St-Pierre; Lise Robidoux; Lucienne Bourque

doi:10.1002/art.1780360609

Low-dose methotrexate with leucovorin (folinic acid) in the management of rheumatoid arthritis. results of a multicenter randomized, double-blind, placebo-controlled trial

Arthritis & Rheumatism ◽

10.1002/art.1780360609 ◽

1993 ◽

Vol 36 (6) ◽

pp. 795-803 ◽

Cited By ~ 83

Author(s):

Jeffrey B. Shiroky ◽

Carolyn Neville ◽

John M. Esdaile ◽

Denis Choquette ◽

Michel Zummer ◽

...

Keyword(s):

Rheumatoid Arthritis ◽

Folinic Acid ◽

Low Dose ◽

Controlled Trial ◽

Double Blind ◽

Double Blind Placebo ◽

Dose Methotrexate

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Positive effect of alendronate on bone mineral density and markers of bone turnover in patients with rheumatoid arthritis on chronic treatment with low-dose prednisone: a randomized, double-blind, placebo-controlled trial

Osteoporosis International ◽

10.1007/s00198-005-0037-2 ◽

2006 ◽

Vol 17 (5) ◽

pp. 716-723 ◽

Cited By ~ 48

Author(s):

W. F. Lems ◽

M. C. Lodder ◽

P. Lips ◽

J. W. J. Bijlsma ◽

P. Geusens ◽

...

Keyword(s):

Rheumatoid Arthritis ◽

Chronic Treatment ◽

Low Dose ◽

Controlled Trial ◽

Mineral Density ◽

Double Blind ◽

Double Blind Placebo ◽

Markers Of Bone Turnover ◽

Positive Effect ◽

Dose Prednisone

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Very low-dose prednisolone in early rheumatoid arthritis retards radiographic progression over two years: A multicenter, double-blind, placebo-controlled trial

Arthritis & Rheumatism ◽

10.1002/art.21421 ◽

2005 ◽

Vol 52 (11) ◽

pp. 3371-3380 ◽

Cited By ~ 175

Author(s):

Siegfried Wassenberg ◽

Rolf Rau ◽

Paul Steinfeld ◽

Henning Zeidler ◽

Keyword(s):

Rheumatoid Arthritis ◽

Early Rheumatoid Arthritis ◽

Low Dose ◽

Radiographic Progression ◽

Controlled Trial ◽

Double Blind ◽

Double Blind Placebo

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Adverse Effects of Low‐Dose Methotrexate in a Randomized Double‐Blind Placebo‐Controlled Trial: Adjudicated Hematologic and Skin Cancer Outcomes in the Cardiovascular Inflammation Reduction Trial

ACR Open Rheumatology ◽

10.1002/acr2.11187 ◽

2020 ◽

Vol 2 (12) ◽

pp. 697-704

Author(s):

Kathleen M.M. Vanni ◽

Nancy Berliner ◽

Nina P. Paynter ◽

Robert J. Glynn ◽

Jean MacFadyen ◽

...

Keyword(s):

Skin Cancer ◽

Adverse Effects ◽

Low Dose ◽

Controlled Trial ◽

Cancer Outcomes ◽

Double Blind ◽

Double Blind Placebo ◽

Dose Methotrexate

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Effects of melatonin supplementation on disease activity, oxidative stress, inflammatory, and metabolic parameters in patients with rheumatoid arthritis: a randomized double-blind placebo-controlled trial

Clinical Rheumatology ◽

10.1007/s10067-021-05670-2 ◽

2021 ◽

Author(s):

Kamal Esalatmanesh ◽

Amirhossein Loghman ◽

Roozbeh Esalatmanesh ◽

Zahra Soleimani ◽

Alireza Khabbazi ◽

...

Keyword(s):

Rheumatoid Arthritis ◽

Oxidative Stress ◽

Disease Activity ◽

Controlled Trial ◽

Metabolic Parameters ◽

Double Blind ◽

Double Blind Placebo

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Effects of low dose ramipril on cardiovascular and renal outcomes in patients with type 2 diabetes and raised excretion of urinary albumin: randomised, double blind, placebo controlled trial (the DIABHYCAR study)

BMJ ◽

10.1136/bmj.328.7441.686-b ◽

2004 ◽

Vol 328 (7441) ◽

pp. 686.3

Keyword(s):

Type 2 Diabetes ◽

Low Dose ◽

Controlled Trial ◽

Urinary Albumin ◽

Double Blind ◽

Double Blind Placebo ◽

Renal Outcomes

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ADDING LOW-DOSE CYCLOSPORIN A TO PARENTERAL GOLD THERAPY IN RHEUMATOID ARTHRITIS: A DOUBLE-BLIND PLACEBO-CONTROLLED STUDY

Rheumatology ◽

10.1093/rheumatology/35.11.1142 ◽

1995 ◽

Vol 35 (11) ◽

pp. 1142-1149 ◽

Cited By ~ 13

Author(s):

G. BENDEX ◽

A. BJELLE

Keyword(s):

Rheumatoid Arthritis ◽

Cyclosporin A ◽

Low Dose ◽

Controlled Study ◽

Double Blind ◽

Gold Therapy ◽

Double Blind Placebo

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Effect of low dose aspirin and dipyridamole on primary patency of arteriovenous grafts in hemodialysis patients: a randomized double-blind placebo-controlled trial

Electronic physician ◽

10.19082/6135 ◽

2018 ◽

Vol 10 (1) ◽

pp. 6135-6139 ◽

Cited By ~ 2

Author(s):

Pouya Tayebi ◽

Gholamhosein Kazemzadeh ◽

Azin Banihashem ◽

Hassan Ravari

Keyword(s):

Low Dose ◽

Controlled Trial ◽

Hemodialysis Patients ◽

Primary Patency ◽

Double Blind ◽

Double Blind Placebo ◽

Dose Aspirin ◽

Low Dose Aspirin ◽

Arteriovenous Grafts

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Methotrexate in resistant juvenile rheumatoid arthritis: Results of the USA–USSR double-blind, placebo-controlled trial

Classic Papers in Rheumatology ◽

10.3109/9780203214237-61 ◽

2001 ◽

pp. 122-123

Keyword(s):

Rheumatoid Arthritis ◽

Juvenile Rheumatoid Arthritis ◽

Controlled Trial ◽

Double Blind ◽

Double Blind Placebo ◽

The Usa

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Effect of chemoprevention by low-dose aspirin of new or recurrent colorectal adenomas in patients with Lynch syndrome (AAS-Lynch): study protocol for a multicenter, double-blind, placebo-controlled randomized controlled trial

Trials ◽

10.1186/s13063-020-04674-8 ◽

2020 ◽

Vol 21 (1) ◽

Author(s):

Adil Soualy ◽

◽

David Deutsch ◽

Mourad Benallaoua ◽

Amal Ait-Omar ◽

...

Keyword(s):

Randomized Controlled Trial ◽

Lynch Syndrome ◽

Low Dose ◽

Controlled Trial ◽

Colorectal Adenomas ◽

Double Blind ◽

Double Blind Placebo ◽

Randomized Controlled ◽

Dose Aspirin ◽

Low Dose Aspirin

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ORAL STEROIDS AS BRIDGE THERAPY IN RHEUMATOID ARTHRITIS PATIENTS STARTING WITH PARENTERAL GOLD. A RANDOMIZED DOUBLE-BLIND PLACEBO-CONTROLLED TRIAL

Rheumatology ◽

10.1093/rheumatology/34.4.347 ◽

1995 ◽

Vol 34 (4) ◽

pp. 347-351 ◽

Cited By ~ 49

Author(s):

A. M. VAN GESTEL ◽

R. F. J. M. LAAN ◽

C. J. HAAGSMA ◽

L. B. A. VAN DE PUTTE ◽

P. L. C. M. VAN RIEL

Keyword(s):

Rheumatoid Arthritis ◽

Controlled Trial ◽

Double Blind ◽

Double Blind Placebo ◽

Oral Steroids ◽

Bridge Therapy

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