scholarly journals Assessment of damage in juvenile-onset systemic lupus erythematosus: A multicenter cohort study

2003 ◽  
Vol 49 (4) ◽  
pp. 501-507 ◽  
Author(s):  
Angelo Ravelli ◽  
Carolina Duarte-Salazar ◽  
Silvia Buratti ◽  
Andreas Reiff ◽  
Bram Bernstein ◽  
...  
Keyword(s):  
Systemic Lupus Erythematosus ◽  
Cohort Study ◽  
Lupus Erythematosus ◽  
Systemic Lupus ◽  
Juvenile Onset ◽  
Multicenter Cohort Study ◽  
Multicenter Cohort ◽  
Onset Systemic Lupus Erythematosus

scholarly journals Neuropsychiatric involvement in juvenile-onset systemic lupus erythematosus: Data from the UK Juvenile-onset systemic lupus erythematosus cohort study

Lupus ◽  
2021 ◽  
pp. 096120332110450
Author(s):  
Teresa Giani ◽  
Eve MD Smith ◽  
Eslam Al-Abadi ◽  
Kate Armon ◽  
Kathryn Bailey ◽  
...  
Keyword(s):  
Systemic Lupus Erythematosus ◽  
Cohort Study ◽  
Lupus Erythematosus ◽  
Significant Proportion ◽  
Damage Index ◽  
Systemic Lupus ◽  
Juvenile Onset ◽  
Protein Levels ◽  
The Uk ◽  
Onset Systemic Lupus Erythematosus

Introduction Juvenile-onset systemic lupus erythematosus (JSLE) is a rare autoimmune/inflammatory disease with significant morbidity and mortality. Neuropsychiatric (NP) involvement is a severe complication, encompassing a heterogeneous range of neurological and psychiatric manifestations. Methods Demographic, clinical, and laboratory features of NP-SLE were assessed in participants of the UK JSLE Cohort Study, and compared to patients in the same cohort without NP manifestations. Results A total of 428 JSLE patients were included in this study, 25% of which exhibited NP features, half of them at first visit. Most common neurological symptoms among NP-JSLE patients included headaches (78.5%), mood disorders (48.6%), cognitive impairment (42%), anxiety (23.3%), seizures (19.6%), movement disorders (17.7%), and cerebrovascular disease (14.9%). Peripheral nervous system involvement was recorded in 7% of NP-SLE patients. NP-JSLE patients more frequently exhibited thrombocytopenia (<100 × 109/L) ( p = 0.04), higher C-reactive protein levels ( p = 0.01), higher global pBILAG score at first visit ( p < 0.001), and higher SLICC damage index score at first ( p = 0.02) and last ( p < 0.001) visit when compared to JSLE patients without NP involvement. Conclusions A significant proportion of JSLE patients experience NP involvement (25%). Juvenile-onset NP-SLE most commonly affects the CNS and is associated with increased overall disease activity and damage.

Bone impairment assessed by HR-pQCT in juvenile-onset systemic lupus erythematosus

2015 ◽  
Vol 27 (5) ◽  
pp. 1839-1848 ◽  
Author(s):  
J. A. Paupitz ◽  
G. L. Lima ◽  
J. C. Alvarenga ◽  
R. M. Oliveira ◽  
E. Bonfa ◽  
...  
Keyword(s):  
Systemic Lupus Erythematosus ◽  
Lupus Erythematosus ◽  
Systemic Lupus ◽  
Juvenile Onset ◽  
Onset Systemic Lupus Erythematosus

HLA-DRB1 antigens in Taiwanese patients with juvenile-onset systemic lupus erythematosus

2001 ◽  
Vol 21 (3) ◽  
pp. 103-105 ◽  
Author(s):  
Huang J.-L. ◽  
Shaw C.-K. ◽  
Lee A. ◽  
Lee T.-D. ◽  
Wu Chou ◽  
...  
Keyword(s):  
Systemic Lupus Erythematosus ◽  
Lupus Erythematosus ◽  
Systemic Lupus ◽  
Juvenile Onset ◽  
Onset Systemic Lupus Erythematosus

scholarly journals Exposure to Air Pollutants and Disease Activity in Juvenile-Onset Systemic Lupus Erythematosus Patients

2015 ◽  
Vol 67 (11) ◽  
pp. 1609-1614 ◽  
Author(s):  
Elisabeth C. Fernandes ◽  
Clovis A. Silva ◽  
Alfésio L. F. Braga ◽  
Adriana M. E. Sallum ◽  
Lúcia M. A. Campos ◽  
...  
Keyword(s):  
Systemic Lupus Erythematosus ◽  
Disease Activity ◽  
Lupus Erythematosus ◽  
Air Pollutants ◽  
Systemic Lupus ◽  
Juvenile Onset ◽  
Onset Systemic Lupus Erythematosus

scholarly journals Oral Ulcers in Juvenile-Onset Systemic Lupus Erythematosus: A Review of the Literature

2017 ◽  
Vol 18 (6) ◽  
pp. 755-762 ◽  
Author(s):  
Pongsawat Rodsaward ◽  
Titipong Prueksrisakul ◽  
Tawatchai Deekajorndech ◽  
Steven W. Edwards ◽  
Michael W. Beresford ◽  
...  
Keyword(s):  
Systemic Lupus Erythematosus ◽  
Lupus Erythematosus ◽  
Review Of The Literature ◽  
Systemic Lupus ◽  
Juvenile Onset ◽  
Oral Ulcers ◽  
Onset Systemic Lupus Erythematosus
Sign in / Sign up

Export Citation Format

Share Document