Synthesis, antitumor activity evaluation, and DNA-binding study of coumarin-based agents

2017 ◽  
Vol 351 (1) ◽  
pp. 1700199 ◽  
Author(s):  
Kamilia M. Amin ◽  
Aly M. Taha ◽  
Riham F. George ◽  
Nada M. Mohamed ◽  
Fardous F. Elsenduny
Keyword(s):  
Dna Binding ◽  
Antitumor Activity ◽  
Binding Study ◽  
Activity Evaluation

A New Samarium(III) Complex of Liriodenine: Synthesis, Crystal Structure, Antitumor Activity, and DNA Binding Study

2019 ◽  
Vol 645 (6-7) ◽  
pp. 570-579 ◽  
Author(s):  
Zhichun Bao ◽  
Delin Lai ◽  
Pengchang Shen ◽  
Mengxin Yu ◽  
Rajesh Kumar ◽  
...  
Keyword(s):  
Crystal Structure ◽  
Dna Binding ◽  
Antitumor Activity ◽  
Binding Study

scholarly journals Synthesis, cytotoxic evaluation and DNA binding study of 9-fluoro-6H-indolo[2,3-b]quinoxaline derivatives

RSC Advances ◽  
2017 ◽  
Vol 7 (66) ◽  
pp. 41869-41879 ◽  
Author(s):  
Zhenyu Gu ◽  
Yanci Li ◽  
Songliang Ma ◽  
Shenghui Li ◽  
Guoqiang Zhou ◽  
...  
Keyword(s):  
Dna Binding ◽  
Antitumor Activity ◽  
Quaternary Ammonium ◽  
Quaternary Ammonium Salts ◽  
Binding Study ◽  
Ammonium Salts ◽  
Binding Ability ◽  
Quinoxaline Derivatives

New quaternary ammonium salts of 9-fluoro-6H-indolo[2,3-b] derivatives were synthesized. These compounds possessed enhanced DNA binding ability and improved antitumor activity.

Synthesis and antitumor activity evaluation of some thienopyrimidine derivatives

2019 ◽  
Vol 50 (3) ◽  
pp. 399-411 ◽  
Author(s):  
Amira T. A. Mohamed ◽  
Mohsen K. Abou-Elregal ◽  
Ahmed S. A. Youssef ◽  
Magdy M. Hemdan ◽  
Sandy S. Samir ◽  
...  
Keyword(s):  
Antitumor Activity ◽  
Activity Evaluation

Synthesis and Antitumor Activity Evaluation of Novel Pyrimidoquinoline Derivatives

2021 ◽  
pp. 1-15
Author(s):  
Mohammad Eghtedari ◽  
Marjan Azimzadeh Arani ◽  
Yaghoub Sarrafi ◽  
Mohammad Shafiei ◽  
Kamal Alimohammadi ◽  
...  
Keyword(s):  
Antitumor Activity ◽  
Activity Evaluation

Water-soluble copper(II) complexes with 4,5-dichloro-isothiazole-3-carboxylic acid and heterocyclic N-donor ligands: Synthesis, crystal structures, cytotoxicity, and DNA binding study

2020 ◽  
Vol 510 ◽  
pp. 119778 ◽  
Author(s):  
Julia A. Eremina ◽  
Elizaveta V. Lider ◽  
Taisiya S. Sukhikh ◽  
Lyubov S. Klyushova ◽  
Maria L. Perepechaeva ◽  
...  
Keyword(s):  
Carboxylic Acid ◽  
Dna Binding ◽  
Crystal Structures ◽  
Water Soluble ◽  
Binding Study ◽  
Donor Ligands

Synthesis and antitumor activity of duocarmycin derivatives: modification at C-8 position of A-ring pyrrole compounds bearing the simplified DNA-binding groups

2000 ◽  
Vol 8 (2) ◽  
pp. 381-391 ◽  
Author(s):  
Nobuyoshi Amishiro ◽  
Satoru Nagamura ◽  
Chikara Murakata ◽  
Akihiko Okamoto ◽  
Eiji Kobayashi ◽  
...  
Keyword(s):  
Dna Binding ◽  
Antitumor Activity

Design, synthesis, and antitumor activity evaluation of steroidal oximes

2021 ◽  
pp. 116360
Author(s):  
Ana R. Gomes ◽  
Ana S. Pires ◽  
Ana M. Abrantes ◽  
Ana C. Gonçalves ◽  
Saul C. Costa ◽  
...  
Keyword(s):  
Antitumor Activity ◽  
Design Synthesis ◽  
Activity Evaluation

Design, synthesis and antitumor activity evaluation of novel HDAC inhibitors with tetrahydrobenzothiazole as the skeleton

2021 ◽  
Vol 108 ◽  
pp. 104652
Author(s):  
Simin Sun ◽  
Wenwen Zhao ◽  
Yongliang Li ◽  
Ziwei Chi ◽  
Xixi Fang ◽  
...  
Keyword(s):  
Antitumor Activity ◽  
Hdac Inhibitors ◽  
Design Synthesis ◽  
Activity Evaluation
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