Design, Synthesis, Biological Evaluation, and Molecular Modeling of Coumarin-Piperazine Derivatives as Acetylcholinesterase Inhibitors

Rahul P. Modh; Sivakumar Prasanth Kumar; Yogesh T. Jasrai; Kishor H. Chikhalia

doi:10.1002/ardp.201300242

Design, Synthesis, Biological Evaluation, and Molecular Modeling of Coumarin-Piperazine Derivatives as Acetylcholinesterase Inhibitors

Archiv der Pharmazie ◽

10.1002/ardp.201300242 ◽

2013 ◽

Vol 346 (11) ◽

pp. 793-804 ◽

Cited By ~ 9

Author(s):

Rahul P. Modh ◽

Sivakumar Prasanth Kumar ◽

Yogesh T. Jasrai ◽

Kishor H. Chikhalia

Keyword(s):

Molecular Modeling ◽

Acetylcholinesterase Inhibitors ◽

Biological Evaluation ◽

Design Synthesis ◽

Piperazine Derivatives

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Novel Thiophene Chalcones-Coumarin as Acetylcholinesterase Inhibitors: Design, Synthesis, Biological Evaluation, Molecular Docking, ADMET Prediction and Molecular Dynamics Simulation

Bioorganic Chemistry ◽

10.1016/j.bioorg.2021.105572 ◽

2021 ◽

pp. 105572

Author(s):

Aso Hameed Hasan ◽

Sankaranarayanan Murugesan ◽

Syazwani Itri Amran ◽

Subhash Chander ◽

Mohammed M. Alanazi ◽

...

Keyword(s):

Molecular Dynamics ◽

Molecular Docking ◽

Molecular Dynamics Simulation ◽

Acetylcholinesterase Inhibitors ◽

Biological Evaluation ◽

Dynamics Simulation ◽

Design Synthesis

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Design, synthesis and biological evaluation of estradiol-PEG-linked platinum(II) hybrid molecules: Comparative molecular modeling study of three distinct families of hybrids

Steroids ◽

10.1016/j.steroids.2010.09.004 ◽

2011 ◽

Vol 76 (1-2) ◽

pp. 94-103 ◽

Cited By ~ 28

Author(s):

Josée Provencher-Mandeville ◽

Chhanda Debnath ◽

Sanat K. Mandal ◽

Valérie Leblanc ◽

Sophie Parent ◽

...

Keyword(s):

Molecular Modeling ◽

Biological Evaluation ◽

Design Synthesis ◽

Molecular Modeling Study ◽

Hybrid Molecules ◽

Synthesis And Biological Evaluation ◽

Modeling Study

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Design, synthesis, and biological evaluation of 7H-thiazolo[3,2-b]-1,2,4-triazin-7-one derivatives as novel acetylcholinesterase inhibitors

ARKIVOC ◽

10.3998/ark.5550190.0010.a30 ◽

2009 ◽

Vol 2009 (10) ◽

pp. 333-348 ◽

Cited By ~ 11

Author(s):

Si-jie Liu ◽

a Liu Yang ◽

Zhe Jin ◽

Er-fang Huang ◽

David Chi Cheong Wan ◽

...

Keyword(s):

Acetylcholinesterase Inhibitors ◽

Biological Evaluation ◽

Design Synthesis ◽

Synthesis And Biological Evaluation

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Identification of new pyrrolo[2,3-d]pyrimidines as potent VEGFR-2 tyrosine kinase inhibitors: Design, synthesis, biological evaluation and molecular modeling

Bioorganic Chemistry ◽

10.1016/j.bioorg.2018.09.001 ◽

2018 ◽

Vol 81 ◽

pp. 612-629 ◽

Cited By ~ 7

Author(s):

Mai Adel ◽

Rabah A.T. Serya ◽

Deena S. Lasheen ◽

Khaled A.M. Abouzid

Keyword(s):

Molecular Modeling ◽

Tyrosine Kinase ◽

Tyrosine Kinase Inhibitors ◽

Kinase Inhibitors ◽

Biological Evaluation ◽

Design Synthesis

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Discovery of novel 5-methyl-1H -pyrazole derivatives as potential antiprostate cancer agents: Design, synthesis, molecular modeling, and biological evaluation

Chemical Biology & Drug Design ◽

10.1111/cbdd.13173 ◽

2018 ◽

Vol 91 (6) ◽

pp. 1113-1124 ◽

Cited By ~ 1

Author(s):

Daoguang Zhang ◽

Solomon Asnake ◽

Jingya Zhang ◽

Per-Erik Olsson ◽

Guisen Zhao

Keyword(s):

Molecular Modeling ◽

Biological Evaluation ◽

Pyrazole Derivatives ◽

Design Synthesis

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Design, Synthesis, and Biological Evaluation of 7H-Thiazolo[3,2-b]-1,2,4-triazin-7-one Derivatives as Dual Binding Site Acetylcholinesterase Inhibitors

Heterocycles ◽

10.3987/com-18-12820 ◽

2013 ◽

Vol 87 (12) ◽

Author(s):

Chun Hu ◽

Si-Jie Liu ◽

Li-Bo Cui ◽

Hiu-Lan Xu ◽

Tie-Ying Wang ◽

...

Keyword(s):

Binding Site ◽

Acetylcholinesterase Inhibitors ◽

Biological Evaluation ◽

Design Synthesis ◽

Synthesis And Biological Evaluation

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Arylamide as Potential Selective Inhibitor for Matrix Metalloproteinase 9 (MMP9): Design, Synthesis, Biological Evaluation, and Molecular Modeling

Journal of Chemical Information and Modeling ◽

10.1021/acs.jcim.9b00630 ◽

2019 ◽

Vol 60 (1) ◽

pp. 349-359 ◽

Cited By ~ 4

Author(s):

Maywan Hariono ◽

Rina F. Nuwarda ◽

Muhammad Yusuf ◽

Rollando Rollando ◽

Riris I. Jenie ◽

...

Keyword(s):

Molecular Modeling ◽

Matrix Metalloproteinase ◽

Biological Evaluation ◽

Selective Inhibitor ◽

Matrix Metalloproteinase 9 ◽

Design Synthesis ◽

Metalloproteinase 9

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Design, synthesis and biological evaluation of novel copper-chelating acetylcholinesterase inhibitors with pyridine and N-benzylpiperidine fragments

Bioorganic Chemistry ◽

10.1016/j.bioorg.2019.103322 ◽

2019 ◽

Vol 93 ◽

pp. 103322 ◽

Cited By ~ 1

Author(s):

Yeheng Zhou ◽

Wei Sun ◽

Jiale Peng ◽

Hui Yan ◽

Li Zhang ◽

...

Keyword(s):

Acetylcholinesterase Inhibitors ◽

Biological Evaluation ◽

Design Synthesis ◽

Synthesis And Biological Evaluation

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Design, synthesis, biological evaluation and molecular modeling of novel 1H-pyrazolo[3,4-d]pyrimidine derivatives as BRAFV600E and VEGFR-2 dual inhibitors

European Journal of Medicinal Chemistry ◽

10.1016/j.ejmech.2018.05.054 ◽

2018 ◽

Vol 155 ◽

pp. 210-228 ◽

Cited By ~ 12

Author(s):

Yuanyuan Wang ◽

Shanhe Wan ◽

Zhonghuang Li ◽

Yu Fu ◽

Guangfa Wang ◽

...

Keyword(s):

Molecular Modeling ◽

Biological Evaluation ◽

Pyrimidine Derivatives ◽

Design Synthesis ◽

Dual Inhibitors

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Design, Synthesis, and Biological Evaluation of 7H-thiazolo[3,2-b]-1,2,4-triazin-7-one Derivatives as Acetylcholinesterase Inhibitors

Letters in Drug Design & Discovery ◽

10.2174/157018010789869343 ◽

2010 ◽

Vol 7 (1) ◽

pp. 5-8 ◽

Cited By ~ 7

Author(s):

Si-Jie Liu ◽

Liu Yang ◽

Xiao-Guang Liu ◽

Ying Luo ◽

Zi-Jian Cao ◽

...

Keyword(s):

Acetylcholinesterase Inhibitors ◽

Biological Evaluation ◽

Design Synthesis ◽

Synthesis And Biological Evaluation

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