Synthesis and Activity of Novel 5-Substituted Pyrrolo[2,3-d]pyrimidine Analogues as pp60c-Src Tyrosine Kinase Inhibitors

Süreyya Ölgen; Yasemin G Isgör; Tülay Çoban

doi:10.1002/ardp.200700141

Synthesis and Activity of Novel 5-Substituted Pyrrolo[2,3-d]pyrimidine Analogues as pp60c-Src Tyrosine Kinase Inhibitors

Archiv der Pharmazie ◽

10.1002/ardp.200700141 ◽

2008 ◽

Vol 341 (2) ◽

pp. 113-120 ◽

Cited By ~ 13

Author(s):

Süreyya Ölgen ◽

Yasemin G Isgör ◽

Tülay Çoban

Keyword(s):

Tyrosine Kinase ◽

Tyrosine Kinase Inhibitors ◽

Kinase Inhibitors ◽

Src Tyrosine Kinase ◽

Pyrimidine Analogues

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Synthesis and Structure−Activity Relationships of Linear and Conformationally Constrained Peptide Analogues of CIYKYY as Src Tyrosine Kinase Inhibitors

Journal of Medicinal Chemistry ◽

10.1021/jm060334k ◽

2006 ◽

Vol 49 (11) ◽

pp. 3395-3401 ◽

Cited By ~ 13

Author(s):

Anil Kumar ◽

Guofeng Ye ◽

Yuehao Wang ◽

Xiaofeng Lin ◽

Gongqin Sun ◽

...

Keyword(s):

Tyrosine Kinase ◽

Tyrosine Kinase Inhibitors ◽

Kinase Inhibitors ◽

Src Tyrosine Kinase ◽

Conformationally Constrained ◽

Structure Activity Relationships ◽

Structure Activity ◽

Peptide Analogues

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Docking, 3D-QSAR studies and in silico ADME prediction on c-Src tyrosine kinase inhibitors

European Journal of Medicinal Chemistry ◽

10.1016/j.ejmech.2008.07.002 ◽

2009 ◽

Vol 44 (3) ◽

pp. 990-1000 ◽

Cited By ~ 36

Author(s):

Cristina Tintori ◽

Matteo Magnani ◽

Silvia Schenone ◽

Maurizio Botta

Keyword(s):

Tyrosine Kinase ◽

Tyrosine Kinase Inhibitors ◽

In Silico ◽

Kinase Inhibitors ◽

3D Qsar ◽

Src Tyrosine Kinase ◽

Qsar Studies ◽

Adme Prediction ◽

In Silico Adme Prediction

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Synthesis and Biological Evaluation of 3-(Substituted-benzylidene)-1,3-dihydro-indolin Derivatives as Human Protein Kinase CK2 and p60c-Src Tyrosine Kinase Inhibitors

Biological and Pharmaceutical Bulletin ◽

10.1248/bpb.30.715 ◽

2007 ◽

Vol 30 (4) ◽

pp. 715-718 ◽

Cited By ~ 23

Author(s):

Süreyya Ölgen ◽

Claudia Götz ◽

Joachim Jose

Keyword(s):

Protein Kinase ◽

Tyrosine Kinase ◽

Tyrosine Kinase Inhibitors ◽

Protein Kinase Ck2 ◽

Kinase Inhibitors ◽

Biological Evaluation ◽

Src Tyrosine Kinase ◽

Human Protein Kinase ◽

Kinase Ck2 ◽

Synthesis And Biological Evaluation

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Src tyrosine kinase inhibitors in the treatment of lung cancer: rationale and clinical data

Clinical Investigation ◽

10.4155/cli.12.27 ◽

2012 ◽

Vol 2 (4) ◽

pp. 387-396 ◽

Cited By ~ 2

Author(s):

Sacha I Rothschild ◽

Oliver Gautschi

Keyword(s):

Lung Cancer ◽

Tyrosine Kinase ◽

Tyrosine Kinase Inhibitors ◽

Clinical Data ◽

Kinase Inhibitors ◽

Src Tyrosine Kinase

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Synthesis and evaluation of 2,7-diamino-thiazolo[4,5-d] pyrimidine analogues as anti-tumor epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors

Bioorganic & Medicinal Chemistry Letters ◽

10.1016/j.bmcl.2009.02.067 ◽

2009 ◽

Vol 19 (8) ◽

pp. 2333-2337 ◽

Cited By ~ 75

Author(s):

Ronghui Lin ◽

Sigmond G. Johnson ◽

Peter J. Connolly ◽

Steven K. Wetter ◽

Eva Binnun ◽

...

Keyword(s):

Epidermal Growth Factor Receptor ◽

Growth Factor ◽

Epidermal Growth Factor ◽

Tyrosine Kinase ◽

Tyrosine Kinase Inhibitors ◽

Kinase Inhibitors ◽

Growth Factor Receptor ◽

Egfr Tyrosine Kinase Inhibitors ◽

Epidermal Growth ◽

Pyrimidine Analogues

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Discovering novel quercetin-3-O-amino acid-esters as a new class of Src tyrosine kinase inhibitors

European Journal of Medicinal Chemistry ◽

10.1016/j.ejmech.2008.09.051 ◽

2009 ◽

Vol 44 (5) ◽

pp. 1982-1988 ◽

Cited By ~ 22

Author(s):

He Huang ◽

Qi Jia ◽

Jingui Ma ◽

Guangrong Qin ◽

Yingyi Chen ◽

...

Keyword(s):

Amino Acid ◽

Tyrosine Kinase ◽

Tyrosine Kinase Inhibitors ◽

Kinase Inhibitors ◽

Amino Acid Esters ◽

Src Tyrosine Kinase ◽

New Class ◽

Acid Esters

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ChemInform Abstract: Discovering Novel Quercetin-3-O-amino Acid-esters as a New Class of Src Tyrosine Kinase Inhibitors.

ChemInform ◽

10.1002/chin.200935202 ◽

2009 ◽

Vol 40 (35) ◽

Author(s):

Hong Liu ◽

et al. et al.

Keyword(s):

Amino Acid ◽

Tyrosine Kinase ◽

Tyrosine Kinase Inhibitors ◽

Kinase Inhibitors ◽

Amino Acid Esters ◽

Src Tyrosine Kinase ◽

New Class ◽

Acid Esters

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A 2D image-based method for modeling some c-Src tyrosine kinase inhibitors

Medicinal Chemistry Research ◽

10.1007/s00044-012-0308-3 ◽

2012 ◽

Vol 22 (6) ◽

pp. 3012-3025 ◽

Cited By ~ 3

Author(s):

Mohsen Shahlaei ◽

Alireza Pourhossein

Keyword(s):

Tyrosine Kinase ◽

Tyrosine Kinase Inhibitors ◽

Kinase Inhibitors ◽

Src Tyrosine Kinase

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Conformation-independent QSAR on c-Src tyrosine kinase inhibitors

Chemometrics and Intelligent Laboratory Systems ◽

10.1016/j.chemolab.2014.03.003 ◽

2014 ◽

Vol 134 ◽

pp. 47-52 ◽

Cited By ~ 7

Author(s):

Nieves C. Comelli ◽

Erlinda V. Ortiz ◽

Magdalena Kolacz ◽

Alla P. Toropova ◽

Andrey A. Toropov ◽

...

Keyword(s):

Tyrosine Kinase ◽

Tyrosine Kinase Inhibitors ◽

Kinase Inhibitors ◽

Src Tyrosine Kinase

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Src Tyrosine Kinase Inhibitors: New Perspectives on Their Immune, Antiviral, and Senotherapeutic Potential

Frontiers in Pharmacology ◽

10.3389/fphar.2019.01011 ◽

2019 ◽

Vol 10 ◽

Cited By ~ 5

Author(s):

José Rivera-Torres ◽

Esther San José

Keyword(s):

Tyrosine Kinase ◽

Tyrosine Kinase Inhibitors ◽

Kinase Inhibitors ◽

Src Tyrosine Kinase

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