[N-Methyl-3H]Scopolamine binding sites in the central nervous system of the cockroachPeriplaneta americana

1986 ◽  
Vol 3 (4) ◽  
pp. 339-347 ◽  
Author(s):  
Sarah C. R. Lummis ◽  
David B. Sattelle
1984 ◽  
Vol 62 (8) ◽  
pp. 961-963 ◽  
Author(s):  
James R. Hammond ◽  
Alexander S. Clanachan

Specific binding of [3H]nitrobenzylthioinosine to cortical membranes from several mammalian species was investigated. Rat, mouse, guinea pig, and dog membranes contained an apparent single class of binding sites; there was, however, a marked species-dependent variation in their affinity for [3H]nitrobenzylthioinosine. Rabbit cortical membranes contained two classes of binding sites and the high and low affinity components were similar to those found in guinea pig and dog cortical membranes, respectively. The [3H]nkrobenzylthioinosine binding sites in rat and the low affinity sites in rabbit were atypical in that they exhibited a low affinity for dipyridamole. It is proposed that these latter sites may represent a form of the central nervous system nucleoside transport system which is less susceptible to inhibition by dipyridamole.


1991 ◽  
Vol 16 (3) ◽  
pp. 245-256 ◽  
Author(s):  
Bojidar Stankov ◽  
Franco Fraschini ◽  
Russel J. Reiter

Nature ◽  
1975 ◽  
Vol 258 (5533) ◽  
pp. 349-351 ◽  
Author(s):  
GERTRAUD POLZ-TEJERA ◽  
JAKOB SCHMIDT ◽  
HARVEY J. KARTEN

Sign in / Sign up

Export Citation Format

Share Document