Characterization of two novel antimicrobial peptides from the cuticular extracts of the antTrichomyrmex criniceps(Mayr), (Hymenoptera: Formicidae)

2017 ◽  
Vol 94 (4) ◽  
pp. e21381 ◽  
Author(s):  
Nagachaitanya Bhagavathula ◽  
Venkateshwarlu Meedidoddi ◽  
Simon Bourque ◽  
Reshmy Vimaladevi ◽  
Santoshkumar Kesavakurup ◽  
...  
Keyword(s):  
Antimicrobial Peptides ◽  
Cuticular Extracts

scholarly journals Isolation and characterization of a novel class of plant antimicrobial peptides form Mirabilis jalapa L. seeds.

1992 ◽  
Vol 267 (4) ◽  
pp. 2228-2233 ◽  
Author(s):  
B P Cammue ◽  
M F De Bolle ◽  
F R Terras ◽  
P Proost ◽  
J Van Damme ◽  
...  
Keyword(s):  
Antimicrobial Peptides ◽  
Isolation And Characterization ◽  
Mirabilis Jalapa

Cloning and characterization of two cDNA clones encoding seed-specific antimicrobial peptides from Mirabilis jalapa L.

1995 ◽  
Vol 28 (4) ◽  
pp. 713-721 ◽  
Author(s):  
Miguel F. C. De Bolle ◽  
Kristel Eggermont ◽  
Rachael E. Duncan ◽  
Rupert W. Osborn ◽  
Franky R. G. Terras ◽  
...  
Keyword(s):  
Antimicrobial Peptides ◽  
Cdna Clones ◽  
Mirabilis Jalapa

Design and characterization of novel hybrid antimicrobial peptides based on cecropin A, LL-37 and magainin II

Peptides ◽  
2012 ◽  
Vol 33 (2) ◽  
pp. 197-205 ◽  
Author(s):  
Marc A. Fox ◽  
Joanne E. Thwaite ◽  
David O. Ulaeto ◽  
Timothy P. Atkins ◽  
Helen S. Atkins
Keyword(s):  
Antimicrobial Peptides ◽  
Cecropin A ◽  
Magainin Ii

Optimized Expression and Characterization of Antimicrobial Peptides, LPcin Analogs

2015 ◽  
Vol 36 (4) ◽  
pp. 1148-1154 ◽  
Author(s):  
Ji-Sun Kim ◽  
Ji-Ho Jeong ◽  
Kyung-Sup Kim ◽  
Yongae Kim
Keyword(s):  
Antimicrobial Peptides

Characterization of novel antimicrobial peptides from the skin of the endangered frog Odorrana ishikawae by shotgun cDNA cloning

2011 ◽  
Vol 412 (4) ◽  
pp. 673-677 ◽  
Author(s):  
Eiko Iwakoshi-Ukena ◽  
Miyuki Soga ◽  
Genya Okada ◽  
Tamotsu Fujii ◽  
Masayuki Sumida ◽  
...  
Keyword(s):  
Antimicrobial Peptides ◽  
Cdna Cloning

scholarly journals Blood Compatibility—An Important but Often Forgotten Aspect of the Characterization of Antimicrobial Peptides for Clinical Application

2019 ◽  
Vol 20 (21) ◽  
pp. 5426
Author(s):  
Stephan Harm ◽  
Karl Lohner ◽  
Ute Fichtinger ◽  
Claudia Schildböck ◽  
Jennifer Zottl ◽  
...  
Keyword(s):  
Antimicrobial Peptides ◽  
Chain Length ◽  
Blood Compatibility ◽  
Acyl Chain ◽  
Antimicrobial Properties ◽  
Polymyxin B ◽  
Acyl Chain Length ◽  
Human Blood Cells ◽  
Plasmatic Coagulation

Acylation of antimicrobial peptides mimics the structure of the natural lipopeptide polymyxin B, and increases antimicrobial and endotoxin-neutralizing activities. In this study, the antimicrobial properties of lactoferrin-based LF11 peptides as well as blood compatibility as a function of acyl chain length were investigated. Beyond the classical hemolysis test, the biocompatibility was determined with human leukocytes and platelets, and the influence of antimicrobial peptides (AMPs) on the plasmatic coagulation and the complement system was investigated. The results of this study show that the acylation of cationic peptides significantly reduces blood tolerance. With increasing acyl chain length, the cytotoxicity of LF11 peptides to human blood cells also increased. This study also shows that acylated cationic antimicrobial peptides are inactivated by the presence of heparin. In addition, it could be shown that the immobilization of LF11 peptides leads to a loss of their antimicrobial properties.

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