All-trans retinoic acid affects subcellular localization of a novel BmNIF3l protein: functional deduce and tissue distribution of NIF3l gene from silkworm (Bombyx mori)

2010 ◽  
Vol 74 (4) ◽  
pp. 217-231 ◽  
Author(s):  
Jianqing Chen ◽  
Qijing Gai ◽  
Zhengbing Lv ◽  
Jian Chen ◽  
Zuoming Nie ◽  
...  
Keyword(s):  
Retinoic Acid ◽  
Subcellular Localization ◽  
Tissue Distribution ◽  
Bombyx Mori ◽  
Trans Retinoic Acid ◽  
All Trans Retinoic Acid ◽  
Silkworm Bombyx Mori

scholarly journals Generation of Retinaldehyde for Retinoic Acid Biosynthesis

Biomolecules ◽  
2019 ◽  
Vol 10 (1) ◽  
pp. 5 ◽  
Author(s):  
Olga V. Belyaeva ◽  
Mark K. Adams ◽  
Kirill M. Popov ◽  
Natalia Y. Kedishvili
Keyword(s):  
Retinoic Acid ◽  
Vitamin A ◽  
Tissue Distribution ◽  
Acid Biosynthesis ◽  
Physiological Processes ◽  
Current State ◽  
Trans Retinoic Acid ◽  
Irreversible Oxidation ◽  
All Trans Retinoic Acid ◽  
Retinoic Acid Biosynthesis

The concentration of all-trans-retinoic acid, the bioactive derivative of vitamin A, is critically important for the optimal performance of numerous physiological processes. Either too little or too much of retinoic acid in developing or adult tissues is equally harmful. All-trans-retinoic acid is produced by the irreversible oxidation of all-trans-retinaldehyde. Thus, the concentration of retinaldehyde as the immediate precursor of retinoic acid has to be tightly controlled. However, the enzymes that produce all-trans-retinaldehyde for retinoic acid biosynthesis and the mechanisms responsible for the control of retinaldehyde levels have not yet been fully defined. The goal of this review is to summarize the current state of knowledge regarding the identities of physiologically relevant retinol dehydrogenases, their enzymatic properties, and tissue distribution, and to discuss potential mechanisms for the regulation of the flux from retinol to retinaldehyde.

scholarly journals Generation of Retinaldehyde for Retinoic Acid Biosynthesis

2019 ◽  
Author(s):  
Olga V. Belyaeva ◽  
Mark K. Adams ◽  
Kirill M. Popov ◽  
Natalia Y. Kedishvili
Keyword(s):  
Retinoic Acid ◽  
Vitamin A ◽  
Tissue Distribution ◽  
Acid Biosynthesis ◽  
Physiological Processes ◽  
Current State ◽  
Trans Retinoic Acid ◽  
Irreversible Oxidation ◽  
All Trans Retinoic Acid ◽  
Retinoic Acid Biosynthesis

The concentration of all-trans-retinoic acid, the bioactive derivative of vitamin A, is critically important for the optimal performance of numerous physiological processes. Either too little or too much of retinoic acid in developing or adult tissues is equally harmful. All-trans-retinoic acid is produced by the irreversible oxidation of all-trans-retinaldehyde. Thus, the concentration of retinaldehyde as the immediate precursor of retinoic acid has to be tightly controlled. However, the enzymes that produce all-trans-retinaldehyde for retinoic acid biosynthesis and the mechanisms responsible for the control of retinaldehyde levels have not yet been fully defined. The goal of this review is to summarize the current state of knowledge regarding the identities of physiologically relevant retinol dehydrogenases, their enzymatic properties and tissue distribution, and to discuss potential mechanisms for the regulation of the flux from retinol to retinaldehyde.

Antiproliferative effect of all-trans-retinoic acid in cholangiocarcinoma

2017 ◽  
Author(s):  
A Prawan ◽  
S Butsri ◽  
V Kukongviriyapan ◽  
L Senggunprai ◽  
S Kongpetch
Keyword(s):  
Retinoic Acid ◽  
Antiproliferative Effect ◽  
Trans Retinoic Acid ◽  
All Trans Retinoic Acid
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