Expression of the matrix metalloproteinases 2 and 9 in the rat small intestine during intrauterine and postnatal life

2019 ◽  
Vol 303 (11) ◽  
pp. 2839-2846
Author(s):  
Camila Audrey dos Reis ◽  
Maria Albertina Miranda Soares ◽  
José Rosa Gomes
Keyword(s):  
Small Intestine ◽  
Matrix Metalloproteinases ◽  
Postnatal Life ◽  
Rat Small Intestine ◽  
The Matrix

scholarly journals Are the Matrix Metalloproteinases 2 and 9 beeing expressed in the mucosa of the rat small intestine during its intrauterine and postnatal life development ?

2019 ◽  
Author(s):  
Camila Audrey dos Reis ◽  
José Rosa Gomes
Keyword(s):  
Innate Immunity ◽  
Small Intestine ◽  
Mast Cells ◽  
Lamina Propria ◽  
Goblet Cells ◽  
Postnatal Life ◽  
Rat Small Intestine ◽  
The Matrix ◽  
Intestine Mucosa ◽  
Masson Trichrome Staining

ABSTRACTMMP-2 and MMP-9 are proteins with well stablished roles on the remodeling of tissue during morphogenesis. This study aimed to evaluate the activity and expression of the MMP-2 and MMP-9 in the rat small intestine mucosa layer on 15th and 18th days of intratuterine life (i.u.) and at 3rd, 10th, 17th, 25th, and 32th days after birth (a.b.). Samples were submitted to zimography, immunohistochemistry methods and Masson trichrome staining. Results showed that MMP-2 and MMP-9 were not expressed in the small intestine epithelium during intrauterine life. MMP-9 was immunolocalized in the villi goblet cells and in the lamina propria in cells identified as being the mast cells (a.b.). We concluded that in the i.u. and a.b. life the MMP-2 and MMP-9 were not expressed in the small intestine epithelium. However, after birth, because MMP-9 was expressed in the mast cels present in the lamina propria it may be involved in the remodeling process of the innate immunity that occurs during the small intestine development.

In situ demonstration of migration of dendritic cells released from rat small intestine to mesenteric lymph nodes

2001 ◽  
Vol 120 (5) ◽  
pp. A183-A183
Author(s):  
H KOBAYASHI ◽  
H NAGATA ◽  
S MIURA ◽  
T AZUMA ◽  
H SUZUKI ◽  
...  
Keyword(s):  
Dendritic Cells ◽  
Small Intestine ◽  
Lymph Nodes ◽  
Rat Small Intestine ◽  
Mesenteric Lymph Nodes ◽  
Mesenteric Lymph

Anti-inflammatory effect of STW 5, STW 6 and isolated extracts on the rat small intestine

2008 ◽  
Vol 29 (S 1) ◽  
Author(s):  
K Nieber ◽  
S Michael ◽  
K Grötzinger ◽  
JW Rauwald ◽  
O Kelber
Keyword(s):  
Small Intestine ◽  
Rat Small Intestine ◽  
Anti Inflammatory ◽  
Inflammatory Effect

Oral vanadate reduces Na(+)-dependent glucose transport in rat small intestine

Diabetes ◽  
1993 ◽  
Vol 42 (8) ◽  
pp. 1126-1132 ◽  
Author(s):  
K. L. Madsen ◽  
V. M. Porter ◽  
R. N. Fedorak
Keyword(s):  
Small Intestine ◽  
Glucose Transport ◽  
Rat Small Intestine
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