scholarly journals Morphological and Cellular Characterization of the Fetal Canine (Canis lupus familiaris ) Subventricular Zone, Rostral Migratory Stream, and Olfactory Bulb

2018 ◽  
Vol 301 (9) ◽  
pp. 1570-1584 ◽  
Author(s):  
Dailiany Orechio ◽  
Bruna Andrade Aguiar ◽  
Giovanne Baroni Diniz ◽  
Jackson Cioni Bittencourt ◽  
Carlos A. S. Haemmerle ◽  
...  
Keyword(s):  
Olfactory Bulb ◽  
Canis Lupus ◽  
Subventricular Zone ◽  
Rostral Migratory Stream ◽  
Canis Lupus Familiaris ◽  
Migratory Stream

scholarly journals Widespread Doublecortin Expression in the Cerebral Cortex of the Octodon degus

2021 ◽  
Vol 15 ◽  
Author(s):  
Thomas van Groen ◽  
Inga Kadish ◽  
Natalija Popović ◽  
María Caballero Bleda ◽  
Beatriz Baño-Otalora ◽  
...  
Keyword(s):  
Cerebral Cortex ◽  
Olfactory Bulb ◽  
Dentate Gyrus ◽  
Subventricular Zone ◽  
Piriform Cortex ◽  
Rostral Migratory Stream ◽  
Nuclear Antigen ◽  
Octodon Degus ◽  
Rats And Mice ◽  
Migratory Stream

It has been demonstrated that in adulthood rodents show newly born neurons in the subgranular layer (SGL) of the dentate gyrus (DG), and in the subventricular zone (SVZ). The neurons generated in the SVZ migrate through the rostral migratory stream (RMS) to the olfactory bulb. One of the markers of newly generated neurons is doublecortin (DCX). The degu similarly shows significant numbers of DCX-labeled neurons in the SGL, SVZ, and RMS. Further, most of the nuclei of these DCX-expressing neurons are also labeled by proliferating nuclear antigen (PCNA) and Ki67. Finally, whereas in rats and mice DCX-labeled neurons are predominantly present in the SGL and SVZ, with only a few DCX neurons present in piriform cortex, the degu also shows significant numbers of DCX expressing neurons in areas outside of SVZ, DG, and PC. Many areas of neocortex in degu demonstrate DCX-labeled neurons in layer II, and most of these neurons are found in the limbic cortices. The DCX-labeled cells do not stain with NeuN, indicating they are immature neurons.

scholarly journals p27KIP1 Regulates Neurogenesis in the Rostral Migratory Stream and Olfactory Bulb of the Postnatal Mouse

2009 ◽  
Vol 29 (9) ◽  
pp. 2902-2914 ◽  
Author(s):  
X. Li ◽  
X. Tang ◽  
B. Jablonska ◽  
A. Aguirre ◽  
V. Gallo ◽  
...  
Keyword(s):  
Olfactory Bulb ◽  
Rostral Migratory Stream ◽  
Migratory Stream

scholarly journals The dominant functional nicotinic receptor in progenitor cells in the rostral migratory stream is the α3β4 subtype

2013 ◽  
Vol 109 (3) ◽  
pp. 867-872 ◽  
Author(s):  
Geeta Sharma
Keyword(s):  
Olfactory Bulb ◽  
Perceptual Learning ◽  
Progenitor Cells ◽  
Glutamate Release ◽  
Brain Regions ◽  
Odor Discrimination ◽  
Rostral Migratory Stream ◽  
Receptor Expression ◽  
Granule Cell Layer ◽  
Migratory Stream

Addition of newly generated neurons into mature neural circuits in the adult CNS responds to changes in neurotransmitter levels and is tightly coupled to the activity of specific brain regions. This postnatal neurogenesis contributes to plasticity of the olfactory bulb and hippocampus and is thought to play a role in learning and memory, context and odor discrimination, as well as perceptual learning. While acetylcholine plays an important role in odor discrimination and perceptual learning, its role in adult neurogenesis in the olfactory bulb has not been elucidated. In this study, I have examined the functional expression of nAChRs in progenitor cells of the rostral migratory stream (RMS) in the adult olfactory bulb of mice. I show that most of these cells in the RMS exhibit large nAChR-mediated calcium transients upon application of acetylcholine (ACh). Unlike in the hippocampus, the predominant functional nAChRs on progenitor cells are of α3β4 subtype. Interestingly, functional receptor expression is lost once progenitor cells mature, and are incorporated into the granule cell layer. Instead, nAChRs are now expressed on some presynaptic terminals and modulate glutamate release onto granule cells. My results imply that ACh is a part of the permissive niche and likely plays a role in development of progenitor cells.

scholarly journals Cellular composition and organization of the subventricular zone and rostral migratory stream in the adult and neonatal common marmoset brain

2011 ◽  
Vol 519 (4) ◽  
pp. 690-713 ◽  
Author(s):  
Kazunobu Sawamoto ◽  
Yuki Hirota ◽  
Clara Alfaro-Cervello ◽  
Mario Soriano-Navarro ◽  
Xiaoping He ◽  
...  
Keyword(s):  
Subventricular Zone ◽  
Common Marmoset ◽  
Rostral Migratory Stream ◽  
Cellular Composition ◽  
Migratory Stream

scholarly journals The Subventricular Zone Continues to Generate Corpus Callosum and Rostral Migratory Stream Astroglia in Normal Adult Mice

2015 ◽  
Vol 35 (9) ◽  
pp. 3756-3763 ◽  
Author(s):  
J. Sohn ◽  
L. Orosco ◽  
F. Guo ◽  
S.-H. Chung ◽  
P. Bannerman ◽  
...  
Keyword(s):  
Corpus Callosum ◽  
Subventricular Zone ◽  
Rostral Migratory Stream ◽  
Normal Adult ◽  
Adult Mice ◽  
Migratory Stream
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