Streptozotocin-Induced Maternal Hyperglycemia Increases the Expression of Antioxidant Enzymes and Mast Cell Number in Offspring Rat Ventral Prostate

2016 ◽  
Vol 300 (2) ◽  
pp. 291-299 ◽  
Author(s):  
Ana C. L. Camargo ◽  
Sérgio A. A. Dos Santos ◽  
Jaqueline C. Rinaldi ◽  
Flavia B. Constantino ◽  
Ketlin T. Colombelli ◽  
...  
Keyword(s):  
Mast Cell ◽  
Antioxidant Enzymes ◽  
Cell Number ◽  
Ventral Prostate ◽  
Maternal Hyperglycemia ◽  
Rat Ventral Prostate ◽  
Mast Cell Number

scholarly journals GPR30 decreases cardiac chymase/angiotensin II by inhibiting local mast cell number

2015 ◽  
Vol 459 (1) ◽  
pp. 131-136 ◽  
Author(s):  
Zhuo Zhao ◽  
Hao Wang ◽  
Marina Lin ◽  
Leanne Groban
Keyword(s):  
Mast Cell ◽  
Angiotensin Ii ◽  
Cell Number ◽  
Mast Cell Number

The expulsion of Echinostoma trivolvis: worm kinetics and intestinal cytopathology in conventional and congenitally athymic BALB/c mice

Parasitology ◽  
1993 ◽  
Vol 106 (3) ◽  
pp. 297-304 ◽  
Author(s):  
T. Fujino ◽  
B. Fried ◽  
I. Tada
Keyword(s):  
Mast Cell ◽  
Goblet Cells ◽  
Cell Number ◽  
Athymic Mice ◽  
Post Exposure ◽  
Mucosal Mast Cells ◽  
Worm Recovery ◽  
Mast Cell Number ◽  
Echinostoma Trivolvis ◽  
Over Time

SUMMARYThe infectivity and distribution of Echinostoma trivolvis were studied in male, conventional and congenitally athymic nude mice, each infected with 30 metacercarial cysts. In conventional mice, worm recoveries at 6 and 8 days post-exposure were58·3 and 54·0%, respectively. Worm recovery declined to 44·0% by day 10, to 4·3% by day 13, and 0% by day 17. In athymic mice, worm recoveries at 6 and 8 days post-exposure were 61·7 and 36·3%, respectively. Worm recovery declined to 27·7% by day 10, to 0·7% by day 13, and 0% by day 17. The distribution of worms demonstrated a posteriad migration over time in both groups. Kinetic changes in the number of goblet and mucosal mast cells in the upper ileum of mice infected with E. trivolvis were examined. In conventional mice, the number of goblet cells increased rapidly to reach a peak at day 13 and then declined gradually. The number of goblet cells in athymic mice also increased to reach a peak at day 13, and then declined rapidly. However, the number of goblet cells in athymic mice was always less than that inconventional mice. The mast cell number in infected conventional mice increased rapidly to reach a peak at day 17 and then declined. There was no increase in the mast cell number of infected athymic mice throughout the experiment. Whereas common pathological changes occurred in the intestines of both mice groups infected with echinostomes some ultrastructural differences were observed in the gut epithelial cells of conventional versus athymic mice.

Mast Cell Chymase Regulates Dermal Mast Cell Number in Mice

2002 ◽  
Vol 290 (5) ◽  
pp. 1478-1482 ◽  
Author(s):  
Yoshiaki Tomimori ◽  
Tsuyoshi Muto ◽  
Harukazu Fukami ◽  
Kayo Saito ◽  
Chika Horikawa ◽  
...  
Keyword(s):  
Mast Cell ◽  
Cell Number ◽  
Mast Cell Number ◽  
Mast Cell Chymase

Human testicular mast cells contain tryptase: increased mast cell number and altered distribution in the testes of infertile men

2000 ◽  
Vol 74 (2) ◽  
pp. 239-244 ◽  
Author(s):  
Viktor Meineke ◽  
Monica B Frungieri ◽  
Berthold Jessberger ◽  
Hermann-Josef Vogt ◽  
Artur Mayerhofer
Keyword(s):  
Mast Cell ◽  
Mast Cells ◽  
Cell Number ◽  
Infertile Men ◽  
Mast Cell Number

Mast cell number and phenotype in chronic idiopathic urticaria

1995 ◽  
Vol 96 (3) ◽  
pp. 360-364 ◽  
Author(s):  
C SMITH ◽  
C KEPLEY ◽  
L SCHWARTZ ◽  
T LEE
Keyword(s):  
Mast Cell ◽  
Cell Number ◽  
Chronic Idiopathic Urticaria ◽  
Mast Cell Number

Increased mast cell number in human hypertensive nephropathy

2008 ◽  
Vol 295 (4) ◽  
pp. F1103-F1109 ◽  
Author(s):  
Pia Welker ◽  
Stephanie Krämer ◽  
David A. Groneberg ◽  
Hans H. Neumayer ◽  
Sebastian Bachmann ◽  
...  
Keyword(s):  
Mast Cell ◽  
Stem Cell ◽  
Mast Cells ◽  
Stem Cell Factor ◽  
Early Stage ◽  
Cell Number ◽  
Blue Staining ◽  
Cell Phenotype ◽  
Hypertensive Nephropathy ◽  
Mast Cell Number

Mast cells have recently been related to nonallergic chronic organ damage and fibrosis. In the present study, we analyzed mast cell number, localization, and maturation in the kidney of a relatively unique group of middle-aged accident victims with primary essential hypertension and in normotensive controls ( n = 8 per group, Caucasians, predominantly male). Hypertensive kidneys showed a significantly higher degree of arteriolosclerosis. However, glomerular and tubulointerstitial matrix accumulation did not differ significantly to normotensive controls indicating a relatively early stage of hypertensive nephropathy. Using toluidine blue staining, renal mast cell number was found to be fivefold higher in hypertensive subjects compared with normotensive controls. Mast cells were primarily located in the peritubular interstitial spaces, some perivascular, but not in glomeruli. In a series of immunohistological staining studies, mast cell maturation grading showed that expression of early hematopoietic precursor cell marker CD34 did not differ between both groups. In contrast, mast cells were mostly positive for IgE receptor, tryptase, and chymase indicating a mature, differentiated cell phenotype in hypertensive nephropathy. Renal expression of stem cell factor was markedly upregulated in primary hypertension. Kidney macrophage and lymphocyte numbers were similar in both groups. In conclusion, human hypertensive kidney disease shows an early and conspicuous upregulation of stem cell factor along with an increased number of mature mast cells. The results suggest that renal mast cell accumulation may play a role in the pathogenesis of human hypertensive nephropathy.

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