scholarly journals Calbindin-D28K Immunoreactivity in the Human Cerebellar Cortex

2014 ◽  
Vol 297 (7) ◽  
pp. 1306-1315 ◽  
Author(s):  
Paolo Flace ◽  
Loredana Lorusso ◽  
Giuliana Laiso ◽  
Anna Rizzi ◽  
Raffaele Cagiano ◽  
...  
Keyword(s):  
Cerebellar Cortex ◽  
Calbindin D28k ◽  
Human Cerebellar Cortex

Histological and biological developmental characterization of the human cerebellar cortex

2006 ◽  
Vol 24 (6) ◽  
pp. 365-371 ◽  
Author(s):  
Anna Maria Lavezzi ◽  
Giulia Ottaviani ◽  
Lorella Terni ◽  
Luigi Matturri
Keyword(s):  
Cerebellar Cortex ◽  
Human Cerebellar Cortex

scholarly journals Quantification of volumetric morphometry and optical property in the cortex of human cerebellum at micrometer resolution

2021 ◽  
Author(s):  
Chao J. Liu ◽  
William Ammon ◽  
Viviana Siless ◽  
Morgan Fogarty ◽  
Ruopeng Wang ◽  
...  
Keyword(s):  
Optical Property ◽  
Cerebellar Cortex ◽  
Large Scale ◽  
Granular Layer ◽  
Ex Vivo ◽  
Volumetric Analysis ◽  
Disease Assessment ◽  
Subject Variability ◽  
Human Cerebellum ◽  
Human Cerebellar Cortex

AbstractThe surface of the human cerebellar cortex is much more tightly folded than the cerebral cortex. Volumetric analysis of cerebellar morphometry in magnetic resonance imaging studies suffers from insufficient resolution, and therefore has had limited impact on disease assessment. Automatic serial polarization-sensitive optical coherence tomography (as-PSOCT) is an emerging technique that offers the advantages of microscopic resolution and volumetric reconstruction of large-scale samples. In this study, we reconstructed multiple cubic centimeters of ex vivo human cerebellum tissue using as-PSOCT. The morphometric and optical properties of the cerebellar cortex across five subjects were quantified. While the molecular and granular layers exhibited similar mean thickness in the five subjects, the thickness varied greatly between the crown of the folium and the depth of the fissure in the granular layer within subjects. Layer-specific optical property remained homogenous within individual subjects but showed higher cross-subject variability than layer thickness. High-resolution volumetric morphometry and optical property maps of human cerebellar cortex revealed by as-PSOCT have great potential to advance our understanding of cerebellar function and diseases.HighlightsWe reconstructed cubic centimeters of human cerebellar samples at micrometer resolution in five subjects.Thickness of the granular layer varies greatly between the crowns and depths of cerebellar fissures.Cross-subject variability is higher in optical property than cortical morphology.Our results suggest homogenous cell and myelin density in the cortical layers of human cerebellum despite the highly convoluted folding patterns.

MRI-based surface-assisted parcellation of human cerebellar cortex: an anatomically specified method with estimate of reliability

NeuroImage ◽  
2005 ◽  
Vol 25 (4) ◽  
pp. 1146-1160 ◽  
Author(s):  
Nikos Makris ◽  
John E. Schlerf ◽  
Steven M. Hodge ◽  
Christian Haselgrove ◽  
Matthew D. Albaugh ◽  
...  
Keyword(s):  
Cerebellar Cortex ◽  
Human Cerebellar Cortex
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