Distribution of Matrix Proteins in Perichondrium and Periosteum During the Incorporation of Meckel's Cartilage into Ossifying Mandible in Midterm Human Fetuses: An Immunohistochemical Study

2014 ◽  
Vol 297 (7) ◽  
pp. 1208-1217 ◽  
Author(s):  
Shunichi Shibata ◽  
Yujiro Sakamoto ◽  
Tamaki Yokohama-Tamaki ◽  
Gen Murakami ◽  
Baik Hwan Cho
2013 ◽  
Vol 57 (4) ◽  
pp. 39 ◽  
Author(s):  
S. Shibata ◽  
Y. Sakamoto ◽  
O. Baba ◽  
C. Qin ◽  
G. Murakami ◽  
...  

1970 ◽  
Vol 49 (3) ◽  
pp. 626-630 ◽  
Author(s):  
Russell D. Coleman

In human fetuses, the diskomalleolar ligament was found to extend from the articular disk and capsule through the petrotympanic fissure to Meckel's cartilage and the malleus. In the adult, the retrodiskal fibers were continuous with the origin of the anterior ligament of the malleus and from the walls of the petrotympanic fissure.


1995 ◽  
Vol 170 (2) ◽  
pp. 387-396 ◽  
Author(s):  
Kun Sung Chung ◽  
Howard H. Park ◽  
Kang Ting ◽  
Hiroko Takita ◽  
Suneel S. Apte ◽  
...  

2011 ◽  
Vol 218 (5) ◽  
pp. 517-533 ◽  
Author(s):  
Tamaki Yokohama-Tamaki ◽  
Takashi Maeda ◽  
Tetsuya S. Tanaka ◽  
Shunichi Shibata

2020 ◽  
pp. 002203452096011
Author(s):  
M. Farahat ◽  
G.A.S. Kazi ◽  
E.S. Hara ◽  
T. Matsumoto

During orofacial tissue development, the anterior and posterior regions of the Meckel’s cartilage undergo mineralization, while the middle region undergoes degeneration. Despite the interesting and particular phenomena, the mechanisms that regulate the different fates of Meckel’s cartilage, including the effects of biomechanical cues, are still unclear. Therefore, the purpose of this study was to systematically investigate the course of Meckel’s cartilage during embryonic development from a biomechanical perspective. Histomorphological and biomechanical (stiffness) changes in the Meckel’s cartilage were analyzed from embryonic day 12 to postnatal day 0. The results revealed remarkable changes in the morphology and size of chondrocytes, as well as the occurrence of chondrocyte burst in the vicinity of the mineralization site, an often-seen phenomenon preceding endochondral ossification. To understand the effect of biomechanical cues on Meckel’s cartilage fate, a mechanically tuned 3-dimensional hydrogel culture system was used. At the anterior region, a moderately soft environment (10-kPa hydrogel) promoted chondrocyte burst and ossification. On the contrary, at the middle region, a more rigid environment (40-kPa hydrogel) enhanced cartilage degradation by inducing a higher expression of MMP-1 and MMP-13. These results indicate that differences in the biomechanical properties of the surrounding environment are essential factors that distinctly guide the mineralization and degradation of Meckel’s cartilage and would be valuable tools for modulating in vitro cartilage and bone tissue engineering.


Development ◽  
2020 ◽  
Vol 147 (11) ◽  
pp. dev190488 ◽  
Author(s):  
Ceilidh Marchant ◽  
Peter Anderson ◽  
Quenten Schwarz ◽  
Sophie Wiszniak

2012 ◽  
Vol 295 (5) ◽  
pp. 734-741 ◽  
Author(s):  
Rong-Tao Yang ◽  
Chi Zhang ◽  
Yong Liu ◽  
Hai-Hua Zhou ◽  
Zu-Bing Li

2007 ◽  
Vol 23 (2) ◽  
pp. 257-262 ◽  
Author(s):  
Mara Lúcia Fonseca Ferraz ◽  
Aline Mara dos Santos ◽  
Camila Lourencini Cavellani ◽  
Renata Calciolari Rossi ◽  
Rosana Rosa Miranda Corrêa ◽  
...  

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