scholarly journals Behcet's Disease with Active Uveitis: Detection of Serum Protein Biomarkers Using MALDI-TOF-MS

2012 ◽  
Vol 295 (7) ◽  
pp. 1168-1173 ◽  
Author(s):  
Xin Wang ◽  
Mei Fen Zhang ◽  
Jing Xie ◽  
Zhi Li Li ◽  
Peng Wang
Keyword(s):  
Behçet’S Disease ◽  
Serum Protein ◽  
Behcet’S Disease ◽  
Behçet's Disease ◽  
Protein Biomarkers ◽  
Behcet's Disease ◽  
Maldi Tof Ms ◽  
Maldi Tof ◽  
Tof Ms

MALDI-TOF/TOF-MS Reveals Elevated Serum Haptoglobin and Amyloid A in Behcet’s Disease

2008 ◽  
Vol 7 (10) ◽  
pp. 4500-4507 ◽  
Author(s):  
Liming Mao ◽  
Hongtao Dong ◽  
Peizeng Yang ◽  
Hongyan Zhou ◽  
Xiangkun Huang ◽  
...  
Keyword(s):  
Behçet’S Disease ◽  
Behcet’S Disease ◽  
Behçet's Disease ◽  
Elevated Serum ◽  
Behcet's Disease ◽  
Amyloid A ◽  
Maldi Tof ◽  
Serum Haptoglobin ◽  
Tof Ms

Discovery of serum protein biomarkers in rheumatoid arthritis using MALDI-TOF-MS combined with magnetic beads

2011 ◽  
Vol 12 (3) ◽  
pp. 145-151 ◽  
Author(s):  
Xiaoxue Zhang ◽  
Zhaolin Yuan ◽  
Bo Shen ◽  
Min Zhu ◽  
Chibo Liu ◽  
...  
Keyword(s):  
Rheumatoid Arthritis ◽  
Serum Protein ◽  
Magnetic Beads ◽  
Protein Biomarkers ◽  
Maldi Tof Ms ◽  
Maldi Tof ◽  
Tof Ms

MALDI-TOF MS-based total serum protein fingerprinting for liver cancer diagnosis

The Analyst ◽  
2019 ◽  
Vol 144 (7) ◽  
pp. 2231-2238 ◽  
Author(s):  
Han-Gyu Park ◽  
Kyoung-Soon Jang ◽  
Hae-Min Park ◽  
Won-Suk Song ◽  
Yoon-Yi Jeong ◽  
...  
Keyword(s):  
Liver Cancer ◽  
Serum Protein ◽  
Cancer Diagnosis ◽  
Total Serum Protein ◽  
Total Serum ◽  
Protein Biomarkers ◽  
Maldi Tof Ms ◽  
Maldi Tof ◽  
Protein Fingerprinting ◽  
Tof Ms

Serum is one of the most commonly used samples in many studies to identify protein biomarkers to diagnose cancer.

scholarly journals Specific serum protein biomarkers of rheumatoid arthritis detected by MALDI-TOF-MS combined with magnetic beads

2010 ◽  
Vol 22 (7) ◽  
pp. 611-618 ◽  
Author(s):  
Q. Niu ◽  
Z. Huang ◽  
Y. Shi ◽  
L. Wang ◽  
X. Pan ◽  
...  
Keyword(s):  
Rheumatoid Arthritis ◽  
Serum Protein ◽  
Magnetic Beads ◽  
Protein Biomarkers ◽  
Maldi Tof Ms ◽  
Maldi Tof ◽  
Specific Serum ◽  
Tof Ms

Coagulation and Fibrinolytic Activity in Behçet's Disease

1991 ◽  
Vol 66 (03) ◽  
pp. 292-294 ◽  
Author(s):  
K K Hampton ◽  
M A Chamberlain ◽  
D K Menon ◽  
J A Davies
Keyword(s):  
Plasminogen Activator ◽  
Tissue Plasminogen Activator ◽  
Behçet’S Disease ◽  
Fibrinolytic Activity ◽  
Behcet’S Disease ◽  
Behçet's Disease ◽  
Plasminogen Activator Inhibitor ◽  
Behcet's Disease ◽  
Tissue Plasminogen ◽  
Von Willebrand

SummaryCoagulation and fibrinolytic activities were studied in 18 subjects with Behçet's disease and compared with results from 14 matched control patients suffering from sero-negative arthritis. Significantly higher plasma concentrations (median and range) were found in Behçet's patients for the following variables: fibrinogen 3.7 (1.7-6.9) vs 3.0 (2.0-5.1) g/1, p <0.05; von Willebrand factor antigen, 115 (72-344) vs 74 (60-119)%, p <0.002; plasminogen activator activity (106/ECLT2) 219 (94-329) vs 137 (78-197) units, p <0.002; tissue plasminogen activator inhibitor (t-PA-I) activity, 9.1 (5.5-19.3) vs 5.1 (1.8-12.0) IU/ml, p <0.002; and PAI-1 antigen, 13.9 (4.5-20.9) vs 6.4 (2.4-11.1) ng/ml, p <0.002. Protein C antigen was significantly lower: 97 (70-183) vs 126 (96-220)%, p <0.02. No differences were observed in antithrombin III activity or antigen, factor VIII coagulant activity, fibrinopeptides A and Bβ15-42, plasminogen, α-2-antiplasmin, functional and immunological tissue-plasminogen activator, thrombin-antithrombin complexes and D-dimer. Levels of tissue plasminogen activator inhibitor (activity and antigen) correlated with disease activity while fibrinogen and von Willebrand factor concentrations did not. Seven of the 18 subjects with Behçet's disease had suffered thrombotic events but it was not possible to distinguish these from the 11 patients without thrombosis using the assays performed. The results suggest the abnormal fibrinolytic activity in Behçet's disease is due to increased inhibition of tissue plasminogen activator. No abnormality of coagulation or fibrinolytic activity specific to Behçet's disease was detected.

Circulating Thrombomodulin as a Clue of Endothelial Damage in Behçet’s Disease

1996 ◽  
Vol 75 (06) ◽  
pp. 974-975 ◽  
Author(s):  
İbrahim C Haznedaroğlu ◽  
Oktay Özdemir ◽  
Osman Özcebe ◽  
Semra V Dündar ◽  
Şerafettin Kirazli
Keyword(s):  
Behçet’S Disease ◽  
Behcet’S Disease ◽  
Behçet's Disease ◽  
Endothelial Damage ◽  
Behcet's Disease
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