Biodegradable cationic waterborne polyurethanes from poly(caprolactone)diol and trimethylol propane monooleate

2021 ◽  
pp. 51622
Author(s):  
Ying Li ◽  
Jun Shen ◽  
Siqi Zhang ◽  
Weidong Wang ◽  
Yu Chen ◽  
...  
Keyword(s):  
Waterborne Polyurethanes ◽  
Poly Caprolactone ◽  
Trimethylol Propane

Synthesis and properties biobased waterborne polyurethanes from glycolysis product of PET waste and poly(caprolactone) diol

2017 ◽  
Vol 105 ◽  
pp. 111-122 ◽  
Author(s):  
Suzana M. Cakić ◽  
Ivan S. Ristić ◽  
Milena M. Cincović ◽  
Nada Č. Nikolić ◽  
Ljubiša B. Nikolić ◽  
...  
Keyword(s):  
Pet Waste ◽  
Waterborne Polyurethanes ◽  
Poly Caprolactone

scholarly journals Preparation and Properties of Biobased, Cationic, Waterborne Polyurethanes Dispersions from Castor Oil and Poly (Caprolactone) Diol

2021 ◽  
Vol 11 (11) ◽  
pp. 4784
Author(s):  
Ying Li ◽  
Sichong Chen ◽  
Jun Shen ◽  
Siqi Zhang ◽  
Ming Liu ◽  
...  
Keyword(s):  
Adhesive Strength ◽  
Castor Oil ◽  
Mechanical Performance ◽  
Aqueous Dispersion ◽  
Waterborne Polyurethane ◽  
Peel Strength ◽  
Waterborne Polyurethanes ◽  
Film Forming ◽  
Poly Caprolactone ◽  
Positive Effect

Biobased cationic waterborne polyurethanes (WPUs) were prepared using isophorone diisocyanate (IPDI), N-methyl diethanolamine (N-MDEA), polycaprolactone (PCL) diol, hydrochlotic acid (HCl), and 1,4-butanediol (BDO). To improve the mechanical performance and adhesive strength of the waterborne polyurethane films, different amounts of castor oil (CO) acting as a cross-linking agent were incorporated in the polyurethane structure. The structures of the waterborne polyurethanes were assessed by Fourier-transform infrared spectroscopy (FTIR). The combination of CO had a positive effect on the dispersion and stability properties of WPUs. WPUs containing higher content of CO demonstrated a remarkable enhancement in homogeneity among particles. The stable aqueous dispersion was obtained even when N-MDEA loading was as low as 3.2 wt%; a bonus of this low hydrophilic moiety was the excellent adhesive strength, whose T-peel strength could reach up to 36.8 N/25 mm, about 114% higher than that of WPU (17.2 N/25 mm) without any CO content. The elongation at break of CO7.40%-WPU was 391%. In addition, the fracture mechanism of the waterborne polyurethane films transformed from the brittle failure to the ductile fracture. The experiment results showed the CO-modified WPUs displayed excellent film-forming property, flexibility, and adhesion, which can be employed for constructing the eco-friendly, biodegradable, cationic, waterborne polyurethanes.

Synthesis of Functionalized Poly(caprolactone)s and Their Application as Micellar Drug Delivery Systems

2013 ◽  
Vol 17 (9) ◽  
pp. 930-942 ◽  
Author(s):  
Jing Hao ◽  
Elizabeth A. Rainbolt ◽  
Katherine Washington ◽  
Michael C. Biewer ◽  
Mihaela C. Stefan
Keyword(s):  
Drug Delivery ◽  
Drug Delivery Systems ◽  
Delivery Systems ◽  
Poly Caprolactone

scholarly journals Optimization of Electrospun Poly(caprolactone) Fiber Diameter for Vascular Scaffolds to Maximize Smooth Muscle Cell Infiltration and Phenotype Modulation

Polymers ◽  
2019 ◽  
Vol 11 (4) ◽  
pp. 643 ◽  
Author(s):  
Dae Geun Han ◽  
Chi Bum Ahn ◽  
Ji-Hyun Lee ◽  
Yongsung Hwang ◽  
Joo Hyun Kim ◽  
...  
Keyword(s):  
Smooth Muscle ◽  
Smooth Muscle Cell ◽  
Muscle Cell ◽  
Fiber Diameter ◽  
Electrospun Fiber ◽  
Electrospun Nanofibers ◽  
Macrophage Infiltration ◽  
Vsmc Proliferation ◽  
Vascular Scaffolds ◽  
Poly Caprolactone

Due to the morphological resemblance between the electrospun nanofibers and extracellular matrix (ECM), electrospun fibers have been widely used to fabricate scaffolds for tissue regeneration. Relationships between scaffold morphologies and cells are cell type dependent. In this study, we sought to determine an optimum electrospun fiber diameter for human vascular smooth muscle cell (VSMC) regeneration in vascular scaffolds. Scaffolds were produced using poly(caprolactone) (PCL) electrospun fiber diameters of 0.5, 0.7, 1, 2, 2.5, 5, 7 or 10 μm, and VSMC survivals, proliferations, infiltrations, and phenotypes were recorded after culturing cells on these scaffolds for one, four, seven, or 10 days. VSMC phenotypes and macrophage infiltrations into scaffolds were evaluated by implanting scaffolds subcutaneously in a mouse for seven, 14, or 28 days. We found that human VSMC survival was not dependent on the electrospun fiber diameter. In summary, increasing fiber diameter reduced VSMC proliferation, increased VSMC infiltration and increased macrophage infiltration and activation. Our results indicate that electrospun PCL fiber diameters of 7 or 10 µm are optimum in terms of VSMC infiltration and macrophage infiltration and activation, albeit at the expense of VSMC proliferation.

scholarly journals A Proposed Fabrication Method of Novel PCL-GEL-HAp Nanocomposite Scaffolds for Bone Tissue Engineering Applications

2010 ◽  
Vol 19 (4) ◽  
pp. 096369351001900 ◽  
Author(s):  
A. Hamlekhan ◽  
M. Mozafari ◽  
N. Nezafati ◽  
M. Azami ◽  
H. Hadipour
Keyword(s):  
Tissue Engineering ◽  
Bone Tissue Engineering ◽  
Bone Tissue ◽  
Mechanical Test ◽  
Fibroblast Cell ◽  
Mouse Fibroblast ◽  
Fabrication Method ◽  
Engineering Applications ◽  
Poly Caprolactone

In this study, poly(∊-caprolactone) (PCL), gelatin (GEL) and nanocrystalline hydroxyapatite (HAp) was applied to fabricate novel PCL-GEL-HAp nanaocomposite scaffolds through a new fabrication method. With the aim of finding the best fabrication method, after testing different methods and solvents, the best method and solvents were found, and the nanocomposites were prepared through layer solvent casting combined with freeze-drying. Acetone and distillated water were used as the PCL and GEL solvents, respectively. The mechanical test showed that the increasing of the PCL weight through the scaffolds caused the improvement of the final nanocomposite mechanical behavior due to the increasing of the ultimate stress, stiffness and elastic modulus (8 MPa for 0% wt PCL to 23.5 MPa for 50% wt PCL). The biomineralization investigation of the scaffolds revealed the formation of bone-like apatite layers after immersion in simulated body fluid (SBF). In addition, the in vitro cytotoxity of the scaffolds using L929 mouse fibroblast cell line (ATCC) indicated no sign of toxicity. These results indicated that the fabricated scaffold possesses the prerequisites for bone tissue engineering applications.

Blends based on biodegradable poly(caprolactone) with outstanding barrier properties for packaging applications: The role of free volume and interactions

2020 ◽  
Vol 135 ◽  
pp. 109869
Author(s):  
María Ángeles Corres ◽  
Álvaro Mayor ◽  
Ainara Sangroniz ◽  
Javier del Río ◽  
Marian Iriarte ◽  
...  
Keyword(s):  
Free Volume ◽  
Barrier Properties ◽  
Biodegradable Poly ◽  
Poly Caprolactone
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