Viscoelastic behavior of hydrogel‐based xanthan gum/aluminum lactate with potential applicability for conformance control

2021 ◽  
pp. 50640
Author(s):  
Camila N. R. Amaral ◽  
Priscila F. Oliveira ◽  
Lucas G. Pedroni ◽  
Claudia R. E. Mansur
Keyword(s):  
Xanthan Gum ◽  
Viscoelastic Behavior ◽  
Conformance Control ◽  
Potential Applicability

The Fractional derivative rheological model and the linear viscoelastic behavior of hydrocolloids

2012 ◽  
Vol 33 (1) ◽  
pp. 141-151 ◽  
Author(s):  
Magdalena Orczykowska ◽  
Marek Dziubiński
Keyword(s):  
Fractional Derivative ◽  
Viscoelastic Properties ◽  
Rheological Model ◽  
Xanthan Gum ◽  
Viscoelastic Behavior ◽  
Rheological Parameters ◽  
Rice Starch ◽  
Linear Viscoelastic Behavior ◽  
Linear Viscoelastic ◽  
The Impact

The Fractional derivative rheological model and the linear viscoelastic behavior of hydrocolloids This study was aimed at evaluating the possibility to use the Friedrich-Braun fractional derivative rheological model to assess the viscoelastic properties of xanthan gum with rice starch and sweet potato starch. The Friedrich-Braun fractional derivative rheological model allows to describe viscoelastic properties comprehensively, starting from the behaviour characteristic of purely viscous fluids to the behaviour corresponding to elastic solids. The Friedrich-Braun fractional derivative rheological model has one more virtue which distinguishes it from other models, it allows to determine the relationship between stress and strain and the impact of each of them on viscoelastic properties on the tested material. An analysis of the data described using the Friedrich-Braun fractional derivative rheological model allows to state that all the tested mixtures of starch with xanthan gum form macromolecular gels exhibiting behaviour typical of viscoelastic quasi-solid bodies. The Friedrich-Braun fractional derivative rheological model and 8 rheological parameters of this model allow to determine changes in the structure of the examined starch - xanthan gum mixtures. Similarly important is the possibility to find out the trend and changes going on in this structure as well as their causes.

Preformed particle gels with potential applicability for conformance control of oil reservoirs

2019 ◽  
Vol 137 (15) ◽  
pp. 48554
Author(s):  
Camila N. R. Amaral ◽  
Priscila F. Oliveira ◽  
Isabella O. Roman ◽  
Claudia R. E. Mansur
Keyword(s):  
Oil Reservoirs ◽  
Conformance Control ◽  
Potential Applicability ◽  
Preformed Particle Gels

An Experimental Investigation of the Primary Atomization of Viscoelastic Impinging Jets

2015 ◽  
Author(s):  
Neil S. Rodrigues ◽  
Jian Gao ◽  
Jun Chen ◽  
Paul Sojka
Keyword(s):  
Xanthan Gum ◽  
Viscoelastic Behavior ◽  
Inertial Force ◽  
Impinging Jets ◽  
Viscoelastic Liquid ◽  
Water Spray ◽  
Spray Formation ◽  
Phase Doppler Anemometry ◽  
Drop Velocity ◽  
The Mean

The primary atomization of a viscoelastic liquid was experimentally investigated using a water-based solution of 0.1 wt.-% xanthan gum (XG). Shadowgraphy images were obtained to qualitatively study the impinging jet spray formation and Phase Doppler Anemometry (PDA) was used to measure the drop diameters and drop velocities. The viscoelastic behavior was observed to hinder atomization when the effect of the inertial force was relatively insignificant. However, increasing the inertial force led to the spray patterns transitioning towards the ligament structures and fully developed patterns. D10, D32, and MMD drop diameters were observed to decrease with increasing inertial force and were larger than mean diameters of a water spray at similar conditions. The mean axial drop velocity was observed to increase with increasing inertial force.

scholarly journals Mucoadhesive Poloxamer-Based Hydrogels for the Release of HP-β-CD-Complexed Dexamethasone in the Treatment of Buccal Diseases

Pharmaceutics ◽  
2021 ◽  
Vol 13 (1) ◽  
pp. 117
Author(s):  
Raul Diaz-Salmeron ◽  
Balthazar Toussaint ◽  
Nicolas Huang ◽  
Etienne Bourgeois Ducournau ◽  
Gabriel Alviset ◽  
...  
Keyword(s):  
Xanthan Gum ◽  
Buccal Cavity ◽  
Viscoelastic Behavior ◽  
Treatment Compliance ◽  
Signs And Symptoms ◽  
Chronic Inflammatory Disease ◽  
Water Soluble ◽  
Poloxamer 407 ◽  
Thermosensitive Hydrogel ◽  
Pharmaceutical Dosage Forms

Oral lichen planus (OLP) is an ongoing and chronic inflammatory disease affecting the mucous membrane of the oral cavity. Currently, the treatment of choice consists in the direct application into the buccal cavity of semisolid formulations containing a corticosteroid molecule to decrease inflammatory signs and symptoms. However, this administration route has shown various disadvantages limiting its clinical use and efficacy. Indeed, the frequency of application and the incorrect use of the preparation may lead to a poor efficacy and limit the treatment compliance. Furthermore, the saliva clearance and the mechanical stress present in the buccal cavity also involve a decrease in the mucosal exposure to the drug. In this context, the design of a new pharmaceutical formulation, containing a steroidal anti-inflammatory, mucoadhesive, sprayable and exhibiting a sustained and controlled release seems to be suitable to overcome the main limitations of the existing pharmaceutical dosage forms. The present work reports the formulation, optimization and evaluation of the mucoadhesive and release properties of a poloxamer 407 thermosensitive hydrogel containing a poorly water-soluble corticosteroid, dexamethasone acetate (DMA), threaded into hydroxypropyl-beta-cyclodextrin (HP-β-CD) molecules. Firstly, physicochemical properties were assessed to ensure suitable complexation of DMA into HP-β-CD cavities. Then, rheological properties, in the presence and absence of various mucoadhesive agents, were determined and optimized. The hydration ratio (0.218–0.191), the poloxamer 407 (15–17 wt%) percentage and liquid-cyclodextrin state were optimized as a function of the gelation transition temperature, viscoelastic behavior and dynamic flow viscosity. Deformation and resistance properties were evaluated in the presence of various mucoadhesive compounds, being the sodium alginate and xanthan gum the most suitable to improve adhesion and mucoadhesion properties. Xanthan gum was shown as the best agent prolonging the hydrogel retention time up to 45 min. Furthermore, xanthan gum has been found as a relevant polymer matrix controlling drug release by diffusion and swelling processes in order to achieve therapeutic concentration for prolonged periods of time.

Study of the modification of bentonite for the formation of nanocomposite hydrogels with potential applicability in conformance control

2020 ◽  
Vol 195 ◽  
pp. 107600 ◽  
Author(s):  
Kelly L.N.P. Aguiar ◽  
Kaique A.B. Pereira ◽  
Matheus S.L. Mendes ◽  
Lucas G. Pedroni ◽  
Priscila F. Oliveira ◽  
...  
Keyword(s):  
Conformance Control ◽  
Nanocomposite Hydrogels ◽  
Potential Applicability

Characteristics of the Frequency-Following Response to Speech in Neonates and Potential Applicability in Clinical Practice: A Systematic Review

2020 ◽  
Vol 63 (5) ◽  
pp. 1618-1635
Author(s):  
Céline Richard ◽  
Mary Lauren Neel ◽  
Arnaud Jeanvoine ◽  
Sharon Mc Connell ◽  
Alison Gehred ◽  
...  
Keyword(s):  
Systematic Review ◽  
Cochrane Library ◽  
Neurodevelopmental Outcomes ◽  
Frequency Following Response ◽  
Ovid Medline ◽  
Published Evidence ◽  
Mesh Terms ◽  
Potential Applicability ◽  
Clinical Potential

Purpose We sought to critically analyze and evaluate published evidence regarding feasibility and clinical potential for predicting neurodevelopmental outcomes of the frequency-following responses (FFRs) to speech recordings in neonates (birth to 28 days). Method A systematic search of MeSH terms in the Cumulative Index to Nursing and Allied HealthLiterature, Embase, Google Scholar, Ovid Medline (R) and E-Pub Ahead of Print, In-Process & Other Non-Indexed Citations and Daily, Web of Science, SCOPUS, COCHRANE Library, and ClinicalTrials.gov was performed. Manual review of all items identified in the search was performed by two independent reviewers. Articles were evaluated based on the level of methodological quality and evidence according to the RTI item bank. Results Seven articles met inclusion criteria. None of the included studies reported neurodevelopmental outcomes past 3 months of age. Quality of the evidence ranged from moderate to high. Protocol variations were frequent. Conclusions Based on this systematic review, the FFR to speech can capture both temporal and spectral acoustic features in neonates. It can accurately be recorded in a fast and easy manner at the infant's bedside. However, at this time, further studies are needed to identify and validate which FFR features could be incorporated as an addition to standard evaluation of infant sound processing evaluation in subcortico-cortical networks. This review identifies the need for further research focused on identifying specific features of the neonatal FFRs, those with predictive value for early childhood outcomes to help guide targeted early speech and hearing interventions.

Toxicological evaluation of xanthan gum based hydrogel formulation in Wistar rats using single dose study

2020 ◽  
Vol 77 (2) ◽  
pp. 353-360
Author(s):  
Nadia Malik ◽  
Mahmood Ahmad ◽  
Muhammad Minhas ◽  
Ruqia Tulain ◽  
Ikrima Khalid ◽  
...  
Keyword(s):  
Single Dose ◽  
Xanthan Gum ◽  
Wistar Rats ◽  
Toxicological Evaluation ◽  
Single Dose Study ◽  
Dose Study ◽  
Hydrogel Formulation

Controlled Release of Metformin Hydrochloride I. In vitro Release from Physical Mixture Containing Xanthan Gum as Hydrophilic Rate Retarding Polymer

1970 ◽  
Vol 4 (1) ◽  
Author(s):  
Mashkura Ashrafi ◽  
Jakir Ahmed Chowdhury ◽  
Md Selim Reza
Keyword(s):  
Controlled Release ◽  
Xanthan Gum ◽  
In Vitro Release ◽  
Correlation Coefficients ◽  
High Ratio ◽  
Water Soluble ◽  
Metformin Hydrochloride ◽  
Model Drug ◽  
Very High

Capsules of different formulations were prepared by using a hydrophilic polymer, xanthan gum and a filler Ludipress. Metformin hydrochloride, which is an anti-diabetic agent, was used as a model drug here with the aim to formulate sustained release capsules. In the first 6 formulations, metformin hydrochloride and xanthan gum were used in different ratio. Later, Ludipress was added to the formulations in a percentage of 8% to 41%. The total procedure was carried out by physical mixing of the ingredients and filling in capsule shells of size ‘1’. As metformin hydrochloride is a highly water soluble drug, the dissolution test was done in 250 ml distilled water in a thermal shaker (Memmert) with a shaking speed of 50 rpm at 370C &plusmn 0.50C for 6 hours. After the dissolution, the data were treated with different kinetic models. The results found from the graphs and data show that the formulations follow the Higuchian release pattern as they showed correlation coefficients greater than 0.99 and the sustaining effect of the formulations was very high when the xanthan gum was used in a very high ratio with the drug. It was also investigated that the Ludipress extended the sustaining effect of the formulation to some extent. But after a certain period, Ludipress did not show any significant effect as the pores made by the xanthan gum network were already blocked. It is found here that when the metformin hydrochloride and the xanthan gum ratio was 1:1, showed a high percentage of drug release, i.e. 91.80% of drug was released after 6 hours. But With a xanthan gum and metformin hydrochloride ratio of 6:1, a very slow release of the drug was obtained. Only 66.68% of the drug was released after 6 hours. The percent loading in this case was 14%. Again, when Ludipress was used in high ratio, it was found to retard the release rate more prominently. Key words: Metformin Hydrochloride, Xanthan Gum, Controlled release capsule Dhaka Univ. J. Pharm. Sci. Vol.4(1) 2005 The full text is of this article is available at the Dhaka Univ. J. Pharm. Sci. website

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