Self‐healing supramolecular waterborne polyurethane dispersions with quadruple hydrogen bonds in main chain

2020 ◽  
Vol 137 (45) ◽  
pp. 49413
Author(s):  
Ziyue Yang ◽  
Dongcheng Sun
Keyword(s):  
Hydrogen Bonds ◽  
Main Chain ◽  
Waterborne Polyurethane ◽  
Self Healing ◽  
Polyurethane Dispersions

An Unparalleled H-bonding and Ion-bonding Crosslinked Waterborne Polyurethane with Super Toughness and Unprecedented Fracture Energy

2021 ◽  
Author(s):  
Yuan Yao ◽  
Bo Liu ◽  
Ziyang Xu ◽  
Jianhai Yang ◽  
Wenguang Liu
Keyword(s):  
Mechanical Properties ◽  
Fracture Energy ◽  
Waterborne Polyurethane ◽  
Self Healing ◽  
Polyurethane Elastomers

Self-healing polyurethane elastomers have been extensively studied; however, developing an eco-friendly self-healable waterborne polyurethane (WPU) with exceptional mechanical properties remains a great challenge. Herein, we report healable, and highly tough...

Self-healing, pH-sensitive and shape memory hydrogels based on acylhydrazone and hydrogen bonds

2021 ◽  
pp. 110838
Author(s):  
Liyuan Qiao ◽  
Chengde Liu ◽  
Cheng Liu ◽  
Lishuai Zong ◽  
Hongjian Gu ◽  
...  
Keyword(s):  
Hydrogen Bonds ◽  
Shape Memory ◽  
Ph Sensitive ◽  
Self Healing

scholarly journals Side chain to main chain hydrogen bonds stabilize a polyglutamine helix in the activation domain of a transcription factor

2018 ◽  
Author(s):  
Albert Escobedo ◽  
Busra Topal ◽  
Micha Ben Achim Kunze ◽  
Juan Aranda ◽  
Giulio Chiesa ◽  
...  
Keyword(s):  
Transcription Factor ◽  
Hydrogen Bonds ◽  
Transcriptional Activity ◽  
Main Chain ◽  
Muscular Atrophy ◽  
Helical Structure ◽  
Structural Basis ◽  
Tract Length ◽  
Spinobulbar Muscular Atrophy ◽  
Polyq Tract

Polyglutamine (polyQ) tracts are regions of low sequence complexity of variable length found in more than one hundred human proteins. These tracts are frequent in activation domains of transcription factors and their length often correlates with transcriptional activity. In addition, in nine proteins, tract elongation beyond specific thresholds causes polyQ disorders. To study the structural basis of the association between tract length, transcriptional activity and disease, here we addressed how the conformation of the polyQ tract of the androgen receptor (AR), a transcription factor associated with the polyQ disease spinobulbar muscular atrophy (SBMA), depends on its length. We found that the tract folds into a helical structure stabilized by unconventional hydrogen bonds between glutamine side chains and main chain carbonyl groups. These bonds are bifurcate with the conventional main chain to main chain hydrogen bonds stabilizing α-helices. In addition, since tract elongation provides additional interactions, the helicity of the polyQ tract directly correlates with its length. These findings suggest a plausible rationale for the association between polyQ tract length and AR transcriptional activity and have implications for establishing the mechanistic basis of SBMA.

Sign in / Sign up

Export Citation Format

Share Document