Biobased isosorbide methacrylate monomer as an alternative to bisphenol A glycerolate dimethacrylate for dental restorative applications

2016 ◽  
Vol 134 (11) ◽  
Author(s):  
María Lydia Berlanga Duarte ◽  
Luis Alberto Reyna Medina ◽  
Patricia Torres Reyes ◽  
Sergio Emmanuel González Pérez ◽  
Ana María Herrera González
Keyword(s):  
Bisphenol A ◽  
Methacrylate Monomer ◽  
Dental Restorative

Potential Toxicity of Bisphenol A and Other Related Substances in Dental Restorative Resins

2015 ◽  
Vol 2 (1) ◽  
Author(s):  
Hazem Abouelleil ◽  
Nina Attik ◽  
Christophe Jeannin ◽  
Pierre Colon ◽  
Brigitte Grosgogeat
Keyword(s):  
Bisphenol A ◽  
Potential Toxicity ◽  
Related Substances ◽  
Dental Restorative

scholarly journals Dental Composites – a Low-Dose Source of Bisphenol A?

2020 ◽  
pp. S295-S304 ◽  
Author(s):  
M. ŠIMKOVÁ ◽  
A. TICHÝ ◽  
M. DUŠKOVÁ ◽  
P. BRADNA
Keyword(s):  
Bisphenol A ◽  
Low Dose ◽  
Daily Intake ◽  
Dental Composite ◽  
Dental Composites ◽  
Mass Spectrometry Detection ◽  
Endocrine Disrupting ◽  
Liquid Chromatography Tandem Mass ◽  
Dental Restorative ◽  
Kinetics Of

Dental composite materials often contain monomers with bisphenol A (BPA) structure in their molecules, e.g. bisphenol-A glycidyl dimethacrylate (Bis-GMA). In this study, it was examined whether dental restorative composites could be a low-dose source of BPA or alternative bisphenols, which are known to have endocrine-disrupting effects. Bis-GMA-containing composites Charisma Classic (CC) and Filtek Ultimate Universal Restorative (FU) and “BPA-free” Charisma Diamond (CD) and Admira Fusion (AF) were examined. Specimens (diameter 6 mm, height 2 mm, n=5) were light-cured from one side for 20 s and stored at 37 °C in methanol which was periodically changed over 130 days to determine the kinetics of BPA release. BPA concentrations were measured using a dansyl chloride derivatization method with liquid chromatography – tandem mass spectrometry detection. The amounts of BPA were expressed in nanograms per gram of composite (ng/g). BPA release from Bis-GMA-containing CC and FU was significantly higher compared to “BPA-free” CD and AF. The highest 1-day release was detected with FU (15.4±0.8 ng/g), followed by CC (9.1±1.1 ng/g), AF (2.1±1.3 ng/g), and CD (1.6±0.8 ng/g), and the release gradually decreased over the examined period. Detected values were several orders of magnitude below the tolerable daily intake (4 µg/kg body weight/day). Alternative bisphenols were not detected. BPA was released even from “BPA-free” composites, although in significantly lower amounts than from Bis-GMA-containing composites. Despite incubation in methanol, detected amounts of BPA were substantially lower than current limits suggesting that dental composites should not pose a health risk if adequately polymerized.

Determination of Endocrine Disruptor Bisphenol-A leakage from Different Matrices of Dental Resin-Based Composite Materials

2021 ◽  
Vol 17 ◽  
Author(s):  
Naser F. Al-Tannak ◽  
Fawaz Alzoubi ◽  
Fatma M. Kareem ◽  
Ladislav Novotny
Keyword(s):  
Bisphenol A ◽  
Endocrine Disruptor ◽  
Binary Solvent ◽  
Small Contribution ◽  
Dental Resin ◽  
Dental Restorative Materials ◽  
Restorative Materials ◽  
Acquity Uplc ◽  
Dental Restorative ◽  
The U.S

Background: Bisphenol A (BPA) derivatives monomers as resins are common components in dental restorative materials and materials used for orthodontic treatment. However, they are a source for BP-A leakage, which can affect adult and child health as an endocrine disruptor. Objective: This study aimed to investigate the level of BPA leakage from four selected weights (0.1, 0.2, 0.3, 0.4 mg) of five different resin combinations used in dental restorative materials. Method: The resin combinations were cured with light for 20 seconds, kept in 1 mL of acetonitrile, and sonicated for 30 minutes. Separation was achieved by using BEH C18 (1.7 μm, 2.1 x 100 mm) analytical column (Waters® Acquity UPLC) and a mobile phase composed of water and acetonitrile (68:32 v/v). Moreover, Waters® Xevo G2-SQToF coupled with Waters® Acquity UPLC system with binary Solvent Manager (I-Class) via electrospray ionization (ESI) interface was used to confirm peaks identities. Results: BPA was detected in all resin combinations and in all selected sample weights. However, BP-A was below the limit of quantification (LOQ) in all selected weights of the Filtek Z350 XT Universal Restorative System. The results show that BPA is still released from selected dental resin combinations available in the market despite the general concern about its potential adverse effects. Conclusion: Nevertheless, the amounts of BPA were within the acceptable levels indicated by the U.S. Environmental Protection Agency and the U.S. Department of Health and Human Services National Toxicology Program and represent a very small contribution to the total BPA exposure. The use of alternative materials such as high-viscosity glass ionomers, inorganic biomaterials, and ceramic would be ideal and healthier for adults and children.

Probing the Chemistry and Spectroscopy of Radiation-Sensitive Polymers by Parallel-Detection EELS

1990 ◽  
Vol 48 (2) ◽  
pp. 34-35
Author(s):  
E. G. Rightor ◽  
G. P. Young
Keyword(s):  
Electron Beam ◽  
Bisphenol A ◽  
Energy Loss ◽  
Parallel Detection ◽  
Commercial Grade ◽  
Incident Electron Beam ◽  
Ptfe Sample ◽  
Spectroscopic Information ◽  
Edge Features ◽  
Electron Energy Loss

Investigation of neat polymers by TEM is often thwarted by their sensitivity to the incident electron beam, which also limits the usefulness of chemical and spectroscopic information available by electron energy loss spectroscopy (EELS) for these materials. However, parallel-detection EELS systems allow reduced radiation damage, due to their far greater efficiency, thereby promoting their use to obtain this information for polymers. This is evident in qualitative identification of beam sensitive components in polymer blends and detailed investigations of near-edge features of homopolymers.Spectra were obtained for a poly(bisphenol-A carbonate) (BPAC) blend containing poly(tetrafluoroethylene) (PTFE) using a parallel-EELS and a serial-EELS (Gatan 666, 607) for comparison. A series of homopolymers was also examined using parallel-EELS on a JEOL 2000FX TEM employing a LaB6 filament at 100 kV. Pure homopolymers were obtained from Scientific Polymer Products. The PTFE sample was commercial grade. Polymers were microtomed on a Reichert-Jung Ultracut E and placed on holey carbon grids.

Bisphenol A

2011 ◽  
pp. 053111130856
Author(s):  
Stephen Ritter
Keyword(s):  
Bisphenol A

A New Hazard From Bisphenol A?

2011 ◽  
pp. 062311292128
Author(s):  
Erika Gebel
Keyword(s):  
Bisphenol A
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