Microgels composed of poly(ethylene imine) and carboxymethoxycoumarin: pH-dependent and photodependent integrity

2012 ◽  
Vol 129 (2) ◽  
pp. 644-651 ◽  
Author(s):  
Hyun Ju Cha ◽  
Jing Dai ◽  
Jin-Chul Kim
Keyword(s):  
Ethylene Imine ◽  
Ph Dependent ◽  
Poly Ethylene

pH-dependent modulation of fibroblast adhesion on multilayers composed of poly(ethylene imine) and heparin

Biomaterials ◽  
2009 ◽  
Vol 30 (28) ◽  
pp. 4939-4947 ◽  
Author(s):  
Marcus S. Niepel ◽  
Dieter Peschel ◽  
Xavier Sisquella ◽  
Josep A. Planell ◽  
Thomas Groth
Keyword(s):  
Ethylene Imine ◽  
Fibroblast Adhesion ◽  
Ph Dependent ◽  
Poly Ethylene

Linear Poly(ethylene imine)-Based Hydrogels for Effective Binding and Release of DNA

2014 ◽  
Vol 15 (4) ◽  
pp. 1124-1131 ◽  
Author(s):  
Christoph Englert ◽  
Lutz Tauhardt ◽  
Matthias Hartlieb ◽  
Kristian Kempe ◽  
Michael Gottschaldt ◽  
...  
Keyword(s):  
Ethylene Imine ◽  
Linear Poly ◽  
Poly Ethylene

Immobilization of poly (ethylene imine) on poly (l-lactide) promotes MG63 cell proliferation and function

2009 ◽  
Vol 20 (11) ◽  
pp. 2317-2326 ◽  
Author(s):  
Zhen-Mei Liu ◽  
Soo-Yeon Lee ◽  
Sukhéna Sarun ◽  
Dieter Peschel ◽  
Thomas Groth
Keyword(s):  
Cell Proliferation ◽  
Mg63 Cell ◽  
Ethylene Imine ◽  
Poly Ethylene ◽  
And Function

scholarly journals Cation, Anion and Ion-Pair Complexes with a G-3 Poly(ethylene imine) Dendrimer in Aqueous Solution

Molecules ◽  
2017 ◽  
Vol 22 (5) ◽  
pp. 816 ◽  
Author(s):  
Matteo Savastano ◽  
Carla Bazzicalupi ◽  
Claudia Giorgi ◽  
Paola Gratteri ◽  
Antonio Bianchi
Keyword(s):  
Aqueous Solution ◽  
Ion Pair ◽  
Ethylene Imine ◽  
Poly Ethylene

scholarly journals Comparison of Linear Poly Ethylene Imine (LPEI) and Poly L-Lysine (PLL) in Fabrication of CHOK1 Cell-Loaded Multilayer Alginate Microcapsules

2020 ◽  
Vol 10 (2) ◽  
pp. 290-296
Author(s):  
Fariba Hajifathaliha ◽  
Arash Mahboubi ◽  
Elham Mohit ◽  
Noushin Bolourchian ◽  
Vahid Khalaj ◽  
...  
Keyword(s):  
Cell Viability ◽  
Cell Survival ◽  
Metabolic Activity ◽  
Encapsulation Efficiency ◽  
Cell Encapsulation ◽  
High Price ◽  
Ethylene Imine ◽  
Linear Poly ◽  
Cellular Metabolic Activity ◽  
Poly Ethylene

Purpose: Poly l-lysine (PLL) has been introduced as a strengthening covering layer for alginate microcapsules which are the most convenient way for cell encapsulation. Some disadvantages of PLL such as high price and low biocompatibility have prompted scientists to find better alternatives. Linear poly ethylene imine (LPEI), thanks to its highly similar structure to PLL, could be considered as a proper cost-effective alternative. In this study LPEI and PLL were compared as covering layers of cell-loaded alginate-LPEI-alginate (cALA) and alginate-PLL-alginate (cAPA) microcapsules. Methods: In addition to the physico-mechanical properties, the encapsulation efficiency, cell survival post encapsulation, cell viability, and cellular metabolic activity within the microcapsules were evaluated using trypan blue, live/dead cell staining, and MTT test, respectively. Results: Physico-mechanical evaluation of the microcapsules revealed that the cell microencapsulation process did not affect their shape, size, and mechanical stability. Although the encapsulation efficiency for cALA and cAPA was not different (P>0.05), cell survival post encapsulation was higher in cALA than in cAPA (P<0.05) which could be the reason for the higher cell viability and also cellular metabolic activity within these microcapsules in comparison to cAPA. Conclusion: Here, based on these results, ALA could be introduced as a preferable alternative to APA for cell encapsulation.

Dopamine-assisted deposition of poly (ethylene imine) for efficient heparinization

2016 ◽  
Vol 144 ◽  
pp. 90-98 ◽  
Author(s):  
Rifang Luo ◽  
Xin Wang ◽  
Jinchuan Deng ◽  
Hao Zhang ◽  
Manfred F. Maitz ◽  
...  
Keyword(s):  
Ethylene Imine ◽  
Poly Ethylene

Integrin ανβ3Targeted Gene Delivery Using RGD Peptidomimetic Conjugates with Copolymers of PEGylated Poly(ethylene imine)

2009 ◽  
Vol 20 (6) ◽  
pp. 1270-1280 ◽  
Author(s):  
Olivia M. Merkel ◽  
Oliver Germershaus ◽  
Carol K. Wada ◽  
Peter J. Tarcha ◽  
Thomas Merdan ◽  
...  
Keyword(s):  
Gene Delivery ◽  
Ethylene Imine ◽  
Poly Ethylene

scholarly journals Hybrid Lipid-Polymer Bilayers: pH-Mediated Interactions between Hybrid Vesicles and Glass

Polymers ◽  
2020 ◽  
Vol 12 (4) ◽  
pp. 745
Author(s):  
Keith L. Willes ◽  
Jasmyn R. Genchev ◽  
Walter F. Paxton
Keyword(s):  
Quartz Crystal ◽  
Solution Ph ◽  
Polymer Vesicles ◽  
Polymer Bilayers ◽  
Poly Ethylene Oxide ◽  
Ph Dependent ◽  
Poly Ethylene ◽  
Glass Surfaces ◽  
Rigid Supports ◽  
Hybrid Bilayers

One practical approach towards robust and stable biomimetic platforms is to generate hybrid bilayers that incorporate both lipids and block co-polymer amphiphiles. The currently limited number of reports on the interaction of glass surfaces with hybrid lipid and polymer vesicles—DOPC mixed with amphiphilic poly(ethylene oxide-b-butadiene) (PEO-PBd)—describe substantially different conclusions under very similar conditions (i.e., same pH). In this study, we varied vesicle composition and solution pH in order to generate a broader picture of spontaneous hybrid lipid/polymer vesicle interactions with rigid supports. Using quartz crystal microbalance with dissipation (QCM-D), we followed the interaction of hybrid lipid-polymer vesicles with borosilicate glass as a function of pH. We found pH-dependent adsorption/fusion of hybrid vesicles that accounts for some of the contradictory results observed in previous studies. Our results show that the formation of hybrid lipid-polymer bilayers is highly pH dependent and indicate that the interaction between glass surfaces and hybrid DOPC/PEO-PBd can be tuned with pH.

scholarly journals Cyclopropenium Nanoparticles and Gene Transfection in Cells

Pharmaceutics ◽  
2020 ◽  
Vol 12 (8) ◽  
pp. 768
Author(s):  
Noam Y. Steinman ◽  
Luis M. Campos ◽  
Yakai Feng ◽  
Abraham J. Domb ◽  
Hossein Hosseinkhani
Keyword(s):  
Viral Vectors ◽  
Gene Transfection ◽  
Medical Science ◽  
Genetic Material ◽  
Mouse Fibroblast ◽  
Ethylene Imine ◽  
Efficient Gene ◽  
Poly Ethylene ◽  
First Time

Non-viral vectors for the transfection of genetic material are at the frontier of medical science. In this article, we introduce for the first time, cyclopropenium-containing nanoparticles as a cationic carrier for gene transfection, as an alternative to the common quaternary ammonium transfection agents. Cyclopropenium-based cationic nanoparticles were prepared by crosslinking poly(ethylene imine) (PEI) with tetrachlorocyclopropene. These nanoparticles were electrostatically complexed with plasmid DNA into nanoparticles (~50 nm). Their cellular uptake into F929 mouse fibroblast cells, and their eventual expression in vitro have been described. Transfection is enhanced relative to PEI with minimal toxicity. These cyclopropenium nanoparticles possess efficient gene transfection capabilities with minimal cytotoxicity, which makes them novel and promising candidates for gene therapy.

scholarly journals Poly(ethylene imine)-Controlled Calcium Phosphate Mineralization

Langmuir ◽  
2008 ◽  
Vol 24 (5) ◽  
pp. 2102-2109 ◽  
Author(s):  
Andriy Shkilnyy ◽  
Alwin Friedrich ◽  
Brigitte Tiersch ◽  
Stefanie Schöne ◽  
Mabya Fechner ◽  
...  
Keyword(s):  
Calcium Phosphate ◽  
Ethylene Imine ◽  
Phosphate Mineralization ◽  
Poly Ethylene
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