Trichloroacetic acid-imprinted polypyrrole film and its property in piezoelectric quartz crystal microbalance and electrochemical sensors to application for determination of haloacetic acids disinfection by-product in drinking water

2007 ◽  
Vol 106 (6) ◽  
pp. 3861-3871 ◽  
Author(s):  
Roongnapa Suedee ◽  
Wimon Intakong ◽  
Peter A. Lieberzeit ◽  
Pikul Wanichapichart ◽  
Pipat Chooto ◽  
...  
Keyword(s):  
Drinking Water ◽  
Quartz Crystal Microbalance ◽  
Trichloroacetic Acid ◽  
Quartz Crystal ◽  
Electrochemical Sensors ◽  
Haloacetic Acids ◽  
Piezoelectric Quartz ◽  
Polypyrrole Film ◽  
Piezoelectric Quartz Crystal

Electrodeless Piezoelectric Quartz Crystal Sensor for Determination of Total Urinary Reducing Sugar

1999 ◽  
Vol 62 (3) ◽  
pp. 328-335 ◽  
Author(s):  
Shi-Hui Si ◽  
Ke-Long Huang ◽  
Chang-Yin Lu ◽  
Shou-Zhuo Yao
Keyword(s):  
Quartz Crystal ◽  
Reducing Sugar ◽  
Piezoelectric Quartz ◽  
Piezoelectric Quartz Crystal

scholarly journals Rapid and Simultaneous Quantification of 4 Urinary Proteins by Piezoelectric Quartz Crystal Microbalance Immunosensor Array

2006 ◽  
Vol 52 (12) ◽  
pp. 2273-2280 ◽  
Author(s):  
Yang Luo ◽  
Ming Chen ◽  
Qianjun Wen ◽  
Meng Zhao ◽  
Bo Zhang ◽  
...  
Keyword(s):  
Quartz Crystal Microbalance ◽  
Quartz Crystal ◽  
Clinical Chemistry ◽  
Label Free ◽  
Urinary Proteins ◽  
Quartz Crystals ◽  
Piezoelectric Quartz ◽  
Piezoelectric Immunosensor ◽  
Highly Sensitive ◽  
Piezoelectric Quartz Crystal

Abstract Background: Urinary proteins are predictive and prognostic markers for diabetes nephropathy. Conventional methods for the quantification of urinary proteins, however, are time-consuming, and most require radioactive labeling. We designed a label-free piezoelectric quartz crystal microbalance (QCM) immunosensor array to simultaneously quantify 4 urinary proteins. Methods: We constructed a 2 × 5 model piezoelectric immunosensor array fabricated with disposable quartz crystals for quantification of microalbumin, α1-microglobulin, β2-microglobulin, and IgG in urine. We made calibration curves after immobilization of antibodies at an optimal concentration and then evaluated the performance characteristics of the immunosensor with a series of tests. In addition, we measured 124 urine samples with both QCM immunosensor array and immunonephelometry to assess the correlation between the 2 methods. Results: With the QCM immunosensor array, we were able to quantify 4 urinary proteins within 15 min. This method had an analytical interval of 0.01–60 mg/L. The intraassay and interassay imprecisions (CVs) were <10%, and the relative recovery rates were 90.3%–109.1%. Nonspecificity of the immunosensor was insignificant (frequency shifts <20 Hz). ROC analyses indicated sensitivities were ≥95.8% and, specificities were ≥76.3%. Bland–Altman difference plots showed the immunosensor array to be highly comparable to immunonephelometry. Conclusions: The QCM system we designed has the advantages of being rapid, label free, and highly sensitive and thus can be a useful supplement to commercial assay methods in clinical chemistry.

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