Metal ion interaction of water-soluble copolymers containing carboxylic acid groups in aqueous phase by membrane filtration technique

2007 ◽  
Vol 105 (5) ◽  
pp. 2893-2902 ◽  
Author(s):  
Guadalupe Del C. Pizarro ◽  
Oscar G. Marambio ◽  
Manuel Jeria-Orell ◽  
Margarita R. Huerta ◽  
Oscar O. Rodríguez ◽  
...  
Keyword(s):  
Carboxylic Acid ◽  
Aqueous Phase ◽  
Metal Ion ◽  
Membrane Filtration ◽  
Water Soluble ◽  
Carboxylic Acid Groups ◽  
Filtration Technique

Metal ion retention properties of water-insoluble polymers containing carboxylic acid groups

2005 ◽  
Vol 99 (3) ◽  
pp. 697-705 ◽  
Author(s):  
Bernabé L. Rivas ◽  
Benita Quilodrán ◽  
Eduardo Quiroz
Keyword(s):  
Carboxylic Acid ◽  
Metal Ion ◽  
Carboxylic Acid Groups ◽  
Insoluble Polymers

Highly concentrated MoS2 nanosheets in water achieved by thioglycolic acid as stabilizer and used as biomarkers

RSC Advances ◽  
2014 ◽  
Vol 4 (81) ◽  
pp. 42936-42941 ◽  
Author(s):  
Rajeshkumar Anbazhagan ◽  
Hsing-Ju Wang ◽  
Hsieh-Chih Tsai ◽  
Ru-Jong Jeng
Keyword(s):  
Quantum Dots ◽  
Carboxylic Acid ◽  
Thioglycolic Acid ◽  
Hydrophobic Surface ◽  
Water Soluble ◽  
Mos2 Nanosheets ◽  
Carboxylic Acid Groups ◽  
Monolayer Nanosheets

Synthesis of water soluble MoS2 quantum dots from the monolayer nanosheets of MoS2, using thioglycolic acid (TGA) was reported in this study. TGA molecules not only exfoliated the bulk of MoS2, but also modified the hydrophobic surface of MoS2 with hydrophilic carboxylic acid groups.

scholarly journals Grafting TRAIL through Either Amino or Carboxylic Groups onto Maghemite Nanoparticles: Influence on Pro-Apoptotic Efficiency

Nanomaterials ◽  
2021 ◽  
Vol 11 (2) ◽  
pp. 502
Author(s):  
Hanene Belkahla ◽  
Andrei Alexandru Constantinescu ◽  
Tijani Gharbi ◽  
Florent Barbault ◽  
Alexandre Chevillot-Biraud ◽  
...  
Keyword(s):  
Carboxylic Acid ◽  
Cancer Therapy ◽  
Computational Study ◽  
Carcinoma Cells ◽  
Maghemite Nanoparticles ◽  
Carboxylic Acid Groups ◽  
Lung Carcinoma Cells ◽  
Biological Studies ◽  
Apoptotic Effect ◽  
Carboxylic Groups

Tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL) is a member of the TNF cytokine superfamily. TRAIL is able to induce apoptosis through engagement of its death receptors DR4 and DR5 in a wide variety of tumor cells while sparing vital normal cells. This makes it a promising agent for cancer therapy. Here, we present two different ways of covalently grafting TRAIL onto maghemite nanoparticles (NPs): (a) by using carboxylic acid groups of the protein to graft it onto maghemite NPs previously functionalized with amino groups, and (b) by using the amino functions of the protein to graft it onto NPs functionalized with carboxylic acid groups. The two resulting nanovectors, NH-TRAIL@NPs-CO and CO-TRAIL@NPs-NH, were thoroughly characterized. Biological studies performed on human breast and lung carcinoma cells (MDA-MB-231 and H1703 cell lines) established these nanovectors are potential agents for cancer therapy. The pro-apoptotic effect is somewhat greater for CO-TRAIL@NPs-NH than NH-TRAIL@NPs-CO, as evidenced by viability studies and apoptosis analysis. A computational study indicated that regardless of whether TRAIL is attached to NPs through an acid or an amino group, DR4 recognition is not affected in either case.

scholarly journals Identification and functional analysis of cadmium-binding protein in the visceral mass of Crassostrea gigas

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Zehua Zheng ◽  
Kazuhiro Kawakami ◽  
Dingkun Zhang ◽  
Lumi Negishi ◽  
Mohamed Abomosallam ◽  
...  
Keyword(s):  
Crassostrea Gigas ◽  
Metal Ion ◽  
Defense Mechanisms ◽  
Three Dimensional ◽  
Tryptophan Fluorescence ◽  
Water Soluble ◽  
Titration Calorimetry ◽  
Visceral Mass ◽  
The Pacific ◽  
Liquid Chromatography Tandem Mass

AbstractThe Pacific oyster, Crassostrea gigas, is a traditional food worldwide. The soft body of the oyster can easily accumulate heavy metals such as cadmium (Cd). To clarify the molecular mechanism of Cd accumulation in the viscera of C. gigas, we identified Cd-binding proteins. 5,10,15,20-Tetraphenyl-21H,23H-porphinetetrasulfonic acid, disulfuric acid, tetrahydrate, and Cd-binding competition experiments using immobilized metal ion affinity chromatography revealed the binding of water-soluble high molecular weight proteins to Cd, including C. gigas protein disulfide isomerase (cgPDI). Liquid chromatography–tandem mass spectrometry (LC–MS/MS) analyses revealed two CGHC motifs in cgPDI. The binding between Cd and rcgPDI was confirmed through a Cd-binding experiment using the TPPS method. Isothermal titration calorimetry (ITC) revealed the binding of two Cd ions to one molecule of rcgPDI. Circular dichroism (CD) spectrum and tryptophan fluorescence analyses demonstrated that the rcgPDI bound to Cd. The binding markedly changed the two-dimensional or three-dimensional structures. The activity of rcgPDI measured by a PDI Activity Assay Kit was more affected by the addition of Cd than by human PDI. Immunological analyses indicated that C. gigas contained cgPDI at a concentration of 1.0 nmol/g (viscera wet weight). The combination of ITC and quantification results revealed that Cd-binding to cgPDI accounted for 20% of the total bound Cd in the visceral mass. The findings provide new insights into the defense mechanisms of invertebrates against Cd.

Water-soluble copper(II) complexes with 4,5-dichloro-isothiazole-3-carboxylic acid and heterocyclic N-donor ligands: Synthesis, crystal structures, cytotoxicity, and DNA binding study

2020 ◽  
Vol 510 ◽  
pp. 119778 ◽  
Author(s):  
Julia A. Eremina ◽  
Elizaveta V. Lider ◽  
Taisiya S. Sukhikh ◽  
Lyubov S. Klyushova ◽  
Maria L. Perepechaeva ◽  
...  
Keyword(s):  
Carboxylic Acid ◽  
Dna Binding ◽  
Crystal Structures ◽  
Water Soluble ◽  
Binding Study ◽  
Donor Ligands
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