Studies on the synthesis and thermal properties of copoly(L-lactic acid/glycolic acid) by direct melt polycondensation

2004 ◽  
Vol 92 (4) ◽  
pp. 2163-2168 ◽  
Author(s):  
Ping Lan ◽  
Yaopeng Zhang ◽  
Qinwei Gao ◽  
Huili Shao ◽  
Xuechao Hu
Keyword(s):  
Lactic Acid ◽  
Thermal Properties ◽  
Glycolic Acid ◽  
Melt Polycondensation ◽  
Direct Melt Polycondensation

Research on the Modification of Poly(L-Lactic Acid) by Glucose via Direct Melt Polycondensation

2011 ◽  
Vol 311-313 ◽  
pp. 1106-1109 ◽  
Author(s):  
Shi He Luo ◽  
Shi Qin Yu ◽  
Jian Xiao Li ◽  
Zhao Yang Wang
Keyword(s):  
Drug Delivery ◽  
Lactic Acid ◽  
Feed Ratio ◽  
Biodegradable Material ◽  
Drug Delivery Application ◽  
H Nmr ◽  
Melt Polycondensation ◽  
Molar Feed Ratio ◽  
Direct Melt Polycondensation

Directly using L-lactic acid (L-LA) and glucose (Glu) as the starting materials, novel biodegradable material poly(L-lactic acid-co-glucose) [P(L-LA-co-Glu)] was synthesized via direct melt polycondensation. The copolymers P(L-LA-co-Glu)s at different molar feed ratios were characterized by FTIR,1H-NMR, GPC, DSC and XRD. All poly(L-lactic acid) modified by Glu was partly crystalline. And their Mw, Tm, and crystallinity basically increased with the increase of the molar feed ratio n(L-LA) : n(Glu). When n(Glu) : n(L-LA) was 1 : 750, the biggest Mw was 5900 Da, and all Mwcould meet the requirement for drug delivery application.

Synthesis of Star-Shaped PLA via Direct Melt Polycondensation: 1. Using L-LA as Starting Material

2010 ◽  
Vol 152-153 ◽  
pp. 1236-1239
Author(s):  
Zhao Yang Wang ◽  
Chao Xu Mao ◽  
Yu Fen Luo ◽  
Shi He Luo ◽  
Jun Min Nan
Keyword(s):  
Drug Delivery ◽  
Lactic Acid ◽  
Low Cost ◽  
Starting Material ◽  
Feed Ratio ◽  
Simple Process ◽  
The Core ◽  
Melt Polycondensation ◽  
Molar Feed Ratio ◽  
Direct Melt Polycondensation

Using 1,3,5-benzenetrioxyundecanol (mTU) as the core, and L-lactic acid (L-LA) as starting material, a novel star-shaped poly(L-lactic acid) (SPLLA) was synthesized via direct melt polycondensation with simple process and low-cost. The obtained biodegradable polymer SPLLA was systematically characterized with the intrinsic viscosity [η], FTIR, 1H-NMR, GPC and XRD. The Mw, Tg, Tm, ΔH, crystallinity, crystallite size of all SPLLA basically increased with the increase of the molar feed ratio n(L-LA) : n(mTU). When n(L-LA) : n(mTU) was 500:1, the biggest Mw was 8600, but all Mw meet the requirement for drug delivery application.

Synthesis of a Biodegradable Material Poly(lactic acid-co-melamine) via Direct Melt Polycondensation

2013 ◽  
Vol 781-784 ◽  
pp. 503-506
Author(s):  
Min Hua Feng ◽  
Jin Feng Xiong ◽  
Qun Fang Wang ◽  
Zhao Yang Wang
Keyword(s):  
Lactic Acid ◽  
Flame Retardant ◽  
Stannous Chloride ◽  
Feed Ratio ◽  
Poly Lactic Acid ◽  
Biodegradable Material ◽  
Melt Polycondensation ◽  
Melt Copolymerization ◽  
Molar Feed Ratio ◽  
Direct Melt Polycondensation

Directly starting fromD,L-lactic acid (LA) and melamine (MA), novel star-shaped biodegradable material poly (lactic acid-co-melamine) [P(LA-co-MA)] as a kind of potential flame retardant is synthesized via melt polycondensation. When the molar feed ration(LA)/n(MA) is 60/1, the optimal synthetic conditions are discussed. After the prepolymerization at 140 °C for 8 h, using 0.4wt% stannous chloride as the catalyst, the melt copolymerization at 160 °C for 8 h gives the copolymer with the biggest intrinsic viscosity 0.87 dLg-1.

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