Diffusion process of amino acids in polymer supports for solid-phase peptide synthesis as studied by pulsed-field-gradient spin-echo proton nuclear magnetic resonance

2003 ◽  
Vol 89 (2) ◽  
pp. 413-421 ◽  
Author(s):  
Yuji Yamane ◽  
Masanori Matsui ◽  
Hideaki Kimura ◽  
Shigeki Kuroki ◽  
Isao Ando
Keyword(s):  
Amino Acids ◽  
Nuclear Magnetic Resonance ◽  
Magnetic Resonance ◽  
Diffusion Process ◽  
Peptide Synthesis ◽  
Solid Phase ◽  
Spin Echo ◽  
Solid Phase Peptide Synthesis ◽  
Proton Nuclear Magnetic Resonance ◽  
Polymer Supports

ChemInform Abstract: 4-Methoxybenzyloxycarbonyl Amino Acids in Solid Phase Peptide Synthesis.

ChemInform ◽  
1988 ◽  
Vol 19 (16) ◽  
Author(s):  
S. S. WANG ◽  
S. T. CHEN ◽  
K. T. WANG ◽  
R. B. MERRIFIELD
Keyword(s):  
Amino Acids ◽  
Peptide Synthesis ◽  
Solid Phase ◽  
Solid Phase Peptide Synthesis

On the use of s-t-butylsulphenyl group for protection of cysteine in solid-phase peptide synthesis using fmoc-amino acids

Tetrahedron ◽  
1987 ◽  
Vol 43 (12) ◽  
pp. 2675-2680 ◽  
Author(s):  
Ramon Eritja ◽  
J.Paige Ziehler-Martin ◽  
Peter A. Walker ◽  
Terry D. Lee ◽  
Kassu Legesse ◽  
...  
Keyword(s):  
Amino Acids ◽  
Peptide Synthesis ◽  
Solid Phase ◽  
Solid Phase Peptide Synthesis

Solid-phase peptide synthesis using Nα-trityl-amino acids

2001 ◽  
Vol 8 (6) ◽  
pp. 331-338
Author(s):  
Beatriz G. de la Torre ◽  
Miguel A. Marcos ◽  
Ramon Eritja ◽  
Fernando albericio
Keyword(s):  
Amino Acids ◽  
Peptide Synthesis ◽  
Solid Phase ◽  
Solid Phase Peptide Synthesis

scholarly journals Correlations between Proton Nuclear Magnetic Resonance Imaging and Retrospective Histochemical Images in Experimental Cerebral Infarction

1985 ◽  
Vol 5 (2) ◽  
pp. 267-274 ◽  
Author(s):  
Hiroyuki Kato ◽  
Kyuya Kogure ◽  
Hitoshi Ohtomo ◽  
Muneshige Tobita ◽  
Shigeru Matsui ◽  
...  
Keyword(s):  
Nuclear Magnetic Resonance ◽  
Magnetic Resonance ◽  
Spin Echo ◽  
Proton Nuclear Magnetic Resonance ◽  
Nmr Imaging ◽  
Resonance Imaging ◽  
H Nmr ◽  
Experimental Cerebral Infarction ◽  
Nuclear Magnetic

Evaluation of ischemic brain injury in experimental cerebral infarction in gerbils and rats was performed by means of both proton nuclear magnetic resonance imaging ([1H]NMR-CT) and various histochemical analyses. In vivo nuclear magnetic resonance (NMR) imaging was carried out employing saturation recovery, inversion recovery, and spin echo pulse sequences. Spatial resolution of the images was excellent. The ischemic lesions were detected with a remarkable contrast in inversion recovery and spin echo images within a few hours after insult. Those changes in NMR images consistently corresponded with the various retrospective histochemical observations, especially with methods related to brain edema (K+ staining) rather than structural (enzymatic) studies. Calculated T1 and T2 relaxation times indicated the evolution of the edema state in the brain in situ. They correlated excellently with the retrospective water content measurement. As a result, detailed characterization of the edema state induced by cerebral ischemia was possible in vivo using [1H]NMR imaging.

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