Graphene oxide‐carboxymethyl cellulose hydrogel beads for uptake and release study of doxorubicin

2021 ◽  
Author(s):  
Aning Ayucitra ◽  
Artik Elisa Angkawijaya ◽  
Yi‐Hsu Ju ◽  
Chintya Gunarto ◽  
Alchris Woo Go ◽  
...  
Keyword(s):  
Graphene Oxide ◽  
Carboxymethyl Cellulose ◽  
Hydrogel Beads ◽  
Cellulose Hydrogel ◽  
Release Study ◽  
Uptake And Release

scholarly journals Preparation and Characterization of Nanoporous Sodium Carboxymethyl Cellulose Hydrogel Beads

2018 ◽  
Vol 2018 ◽  
pp. 1-12 ◽  
Author(s):  
Gulen Oytun Akalin ◽  
Mehlika Pulat
Keyword(s):  
Carboxymethyl Cellulose ◽  
Sem Analysis ◽  
Sodium Carboxymethyl Cellulose ◽  
Nanoporous Structure ◽  
Root Mean Square Roughness ◽  
Gel Content ◽  
Hydrogel Beads ◽  
Force Microscopy ◽  
Cellulose Hydrogel ◽  
Degradation Test

A series of nanoporous sodium carboxymethyl cellulose (NaCMC) hydrogel beads were prepared using FeCl3 ionic crosslinker by changing polymer and crosslinker percentages (%). Characteristics of the hydrogels were investigated by gel content, swelling test, degradation test, Attenuated Total Reflectance-Fourier Transform Infrared (ATR-FTIR), Scanning Electron Microscope/Energy Dispersive X-ray Analysis (SEM/EDX), and Atomic Force Microscopy (AFM). Swelling experiments were studied by changing time, temperature, and pH. The swelling percentage (S%) regularly decreased with increasing the amounts of polymer and crosslinker, in contrast with gel content results. NaCMC hydrogels were found to be sensitive to pH variations. The degradation test showed that hydrogels had good stability and their degradation period varied from 30 to 36 days. According to SEM analysis, NaCMC hydrogels had mostly nanoporous structure. The average granule and pore sizes of the least swollen NaCMC-12 hydrogel were found to be 13.1±0.3 nm and 82.1±3.2 nm. The elemental compositions of hydrogels were determined with EDX. The minimum average surface roughness (Ra) and root mean square roughness (Rms) parameters were found to be 15.7±1.9 nm and 20.3±2.2 nm for NaCMC-12 hydrogels by AFM. Due to their good morphologies, stabilities, and swelling behaviors, NaCMC hydrogels can be suitable for biomaterial applications.

scholarly journals Response surface methodology for optimization of methylene blue adsorption onto carboxymethyl cellulose-based hydrogel beads: adsorption kinetics, isotherm, thermodynamics and reusability studies

RSC Advances ◽  
2019 ◽  
Vol 9 (65) ◽  
pp. 37858-37869 ◽  
Author(s):  
Dalia Allouss ◽  
Younes Essamlali ◽  
Othmane Amadine ◽  
Achraf Chakir ◽  
Mohamed Zahouily
Keyword(s):  
Methylene Blue ◽  
Response Surface Methodology ◽  
Graphene Oxide ◽  
Response Surface ◽  
Adsorption Kinetics ◽  
Carboxymethyl Cellulose ◽  
Environment Friendly ◽  
Hydrogel Beads ◽  
Ionotropic Gelation ◽  
Efficient Adsorbent

Environment-friendly composite hydrogel beads based on carboxymethyl cellulose (CMC), alginate (Alg) and graphene oxide (GO) were synthesized by an ionotropic gelation technique and studied as an efficient adsorbent for methylene blue (MB).

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