Risk Factors of Postoperative Delirium in Older Adult Spine Surgery Patients: A Meta‐Analysis

AORN Journal ◽  
2020 ◽  
Vol 112 (6) ◽  
pp. 650-661
Author(s):  
Wonhee Baek ◽  
Young Man Kim ◽  
Hyangkyu Lee
2019 ◽  
Vol 2019 ◽  
pp. 1-20 ◽  
Author(s):  
Xinjie Wu ◽  
Wei Sun ◽  
Mingsheng Tan

Background. The present study aims to investigate the incidence and risk factors associated with postoperative delirium in patients undergoing spine surgery. Methods. PubMed, EMBASE, Cochrane Library, and Science Citation Index were searched up to August 2019 for studies examining postoperative delirium following spine surgery. Incidence and risk factors associated with delirium were extracted. Odds ratios (OR) and 95% confidence intervals (CI) were calculated for outcomes. The Newcastle–Ottawa Scale (NOS) was used for the study quality evaluation. Results. The final analysis includes a total of 40 studies. The pooled analysis reveals that incidence of delirium is 8%, and there are significant differences for developing delirium in age (OR 1.07; 95% CI 1.04–1.09), age more than 65 (OR 4.77; 95% CI 4.37–5.16), age more than 70 (OR 15.87; 95% CI 6.03–41.73), and age more than 80 (OR 1.91; 95% CI 1.78–2.03) years, male (OR 0.81; 95% CI 0.76–0.86), a history of alcohol abuse (OR 2.11; 95% CI 1.67–2.56), anxiety (OR 1.74; 95% CI 1.04–2.44), congestive heart failure (OR 1.4; 95% CI 1.21–1.6), depression (OR 2.5; 95% CI 1.52–3.49), hypertension (OR 1.12; 95% CI 1.04–1.2), kidney disease (OR 1.41; 95% CI 1.16–1.66), neurological disorder (OR 4.66; 95% CI 4.22–5.11), opioid use (OR 1.86; 95% CI 1.18–2.54), psychoses (OR 2.77; 95% CI 2.29–3.25), pulmonary disease (OR 1.81; 95% CI 1.27–2.35), higher mini-mental state examination (OR 0.7; 95% CI 0.5–0.89), preoperative pain (OR 1.88; 95% CI 1.11–2.64), and postoperative urinary tract infection (OR 5.68; 95% CI 2.41–13.39). Conclusions. A comprehensive understanding of incidence and risk factors of delirium can improve prevention, diagnosis, and management. Risk of postoperative delirium can be reduced based upon identifiable risk factors.


2020 ◽  
Vol 20 (1) ◽  
Author(s):  
Arissara Iamaroon ◽  
Titima Wongviriyawong ◽  
Patumporn Sura-arunsumrit ◽  
Nattikan Wiwatnodom ◽  
Nichakarn Rewuri ◽  
...  

2021 ◽  
Vol 87 (6) ◽  
Author(s):  
Jian ZHOU ◽  
Xiaolin XU ◽  
Yongxin LIANG ◽  
Xueying ZHANG ◽  
Houan TU ◽  
...  

2020 ◽  
Vol 141 ◽  
pp. e894-e920
Author(s):  
Yu Tung Lo ◽  
Michelle Lim-Watson ◽  
Yookyung Seo ◽  
Noemi Fluetsch ◽  
Moudi M. Alasmari ◽  
...  

Spine ◽  
2013 ◽  
Vol 38 (20) ◽  
pp. 1790-1796 ◽  
Author(s):  
Steven J. Fineberg ◽  
Sreeharsha V. Nandyala ◽  
Alejandro Marquez-Lara ◽  
Matthew Oglesby ◽  
Alpesh A. Patel ◽  
...  

2020 ◽  
Vol 15 (1) ◽  
Author(s):  
Hao Jie Zhang ◽  
Xue Hai Ma ◽  
Jin Biao Ye ◽  
Cong Zhi Liu ◽  
Zhi Yang Zhou

Abstract Background Postoperative delirium is a common psychiatric disorder among patients who undergo spinal surgery. The purpose of current meta-analysis was to assess the potential risk factors related to delirium in spinal surgery. Methods We searched the following databases: PubMed, EMBASE, the Cochrane Library, and Web of Science, from inception to July 2020. Two reviewers independently assessed the quality of the included studies using the previously described Newcastle-Ottawa Scale (NOS). We included spinal surgery patients who suffered with delirium or not. Stata 12.0 was used for meta-analysis. Results Thirteen trial studies that met our inclusion criteria were incorporated into the meta-analysis. Postoperative delirium was associated with an increase of the duration of hospital stay (P = 0.044) and increased perioperative readmission rate (P = 0.013) and economic costs (P = 0.002). This meta-analysis demonstrates that there were twenty-two risk factors: general characteristic: old age, female patients, history of surgery, diabetes mellitus, hypertension; preoperative data: low hematocrit, low hemoglobin, low albumin, low sodium, depression; operative data: operating time, total blood loss; postoperative data: low sodium, low hemoglobin, low hematocrit, low albumin, fever, low potassium, blood sugar, and visual analog scale (VAS). Conclusions Delirium not only prolongs the length of hospital stay, but also increases readmission rate and the economic costs. Several risk factors including old age, female patients, history of surgery, diabetes mellitus, low hematocrit, low hemoglobin, low albumin, low sodium, depression; operative data: operating time, total blood loss, low sodium, low hemoglobin, low hematocrit, low albumin, fever, low potassium, blood sugar, and VAS were significant predictors for postoperative delirium after spinal surgery.


2017 ◽  
Vol 47 (6) ◽  
pp. 505-511 ◽  
Author(s):  
Yun Zhu ◽  
Gangpu Wang ◽  
Shengwen Liu ◽  
Shanghui Zhou ◽  
Ying Lian ◽  
...  

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