Reducing the Risk of Surgical Site Infection With Effective Preoperative Patient Skin Antisepsis

AORN Journal ◽  
2020 ◽  
Vol 112 (1) ◽  
pp. 82-83
Author(s):  
Lisa Spruce
Keyword(s):  
Surgical Site Infection ◽  
Site Infection ◽  
Skin Antisepsis ◽  
Preoperative Patient

scholarly journals Chlorhexidine-alcohol versus Povidone-Iodine-alcohol for surgical site antisepsis in caesarean section

2019 ◽  
Vol 8 (4) ◽  
pp. 1359
Author(s):  
Vishnu Priya Kesani ◽  
Sruthi Talasila ◽  
Sheela S. R.
Keyword(s):  
Caesarean Section ◽  
Surgical Site Infection ◽  
Povidone Iodine ◽  
Care Center ◽  
Tertiary Care ◽  
Site Infection ◽  
Healthcare Associated Infection ◽  
Skin Antisepsis ◽  
Control And Prevention ◽  
Healthcare Associated

Background: Caesarean section is one of the most common procedures performed. Recent studies found that surgical-site infection (SSI) was the most common healthcare-associated infection. Authors hypothesized that optimization of preoperative skin antisepsis may decrease postoperative infections. The objective was to establish the efficacy of chlorhexidine-based antiseptic protocol versus povidone-iodine protocol in reducing SSI for patients undergoing caesarean deliveries.Methods: This is a randomized prospective study conducted from April 2017 to September 2017 at a tertiary care center in India. Women who underwent caesarean sections were allocated into either group. Enrolled patients were randomly assigned to have the surgical site painted with chlorhexidine-alcohol preparation or painted with a solution of 10% povidone-iodine and then with surgical spirit. The outcomes were any SSI occurring within a week or during the 30 day follow up period of the surgery including any of: superficial or deep surgical site infection, or endometritis, according to Centers for Disease Control and Prevention definitions.Results: A total of 560 subjects (273 in the chlorhexidine group and 287 in the iodine group) qualified for the study. The number of surgical-site infection was significantly lower in the chlorhexidine group than in the iodine group (6.95% vs. 14.28%; P=0.005). Chlorhexidine–alcohol was significantly more protective than iodine-alcohol against both superficial incisional infections (5.49% vs. 10.10%, P=0.03) and deep incisional infections (1.46% vs. 4.18%, P=0.04).Conclusions: This study highlighted that Chlorhexidine-alcohol provided superior skin antisepsis in comparison to povidone iodine-alcohol.

Skin antisepsis with chlorhexidine versus iodine for the prevention of surgical site infection: A systematic review and meta-analysis

2017 ◽  
Vol 45 (2) ◽  
pp. 180-189 ◽  
Author(s):  
Gaetano Pierpaolo Privitera ◽  
Anna Laura Costa ◽  
Silvio Brusaferro ◽  
Piero Chirletti ◽  
Paola Crosasso ◽  
...  
Keyword(s):  
Systematic Review ◽  
Surgical Site Infection ◽  
Meta Analysis ◽  
Site Infection ◽  
Skin Antisepsis

Comparison of chlorhexidine-isopropanol with isopropanol skin antisepsis for prevention of surgical-site infection after abdominal surgery

2018 ◽  
Vol 105 (7) ◽  
pp. 893-899 ◽  
Author(s):  
J. C. Harnoss ◽  
O. Assadian ◽  
A. Kramer ◽  
P. Probst ◽  
C. Müller-Lantzsch ◽  
...  
Keyword(s):  
Abdominal Surgery ◽  
Surgical Site Infection ◽  
Site Infection ◽  
Skin Antisepsis

scholarly journals Chlorhexidine–alcohol versus povidone–iodine as preoperative skin antisepsis for prevention of surgical site infection in cesarean delivery—a pilot randomized control trial

Trials ◽  
2021 ◽  
Vol 22 (1) ◽  
Author(s):  
Athokpam Lenin Luwang ◽  
Pradip Kumar Saha ◽  
Minakshi Rohilla ◽  
Pooja Sikka ◽  
Lekha Saha ◽  
...  
Keyword(s):  
Surgical Site Infection ◽  
Cesarean Delivery ◽  
Povidone Iodine ◽  
Statistical Significance ◽  
Site Infection ◽  
Skin Preparation ◽  
Alcohol Group ◽  
E Coli ◽  
Skin Antisepsis ◽  
Clinical Trials Registry

Abstract Objectives To compare the efficacy of chlorhexidine–alcohol and povidone–iodine as preoperative antiseptic skin preparation for prevention of surgical site infection (SSI) after cesarean delivery (CD). Materials and methods A total of 311 eligible women who underwent CS were recruited in the study after fulfilling all the eligibility and exclusion criteria. Patients were randomized into two groups (153 in chlorhexidine–alcohol group and 158 in povidone–iodine group) by a computer-generated randomization table. Patients were followed for a period of 30 days in postoperative period to monitor for SSI. Results The rate of SSI in the chlorhexidine–alcohol group is 5.4% and that of the povidone–iodine group is 8.6%. E. coli, K. pneumoniae, and Acinetobacter baumannii were the most common organisms isolated. E. coli was found in 9.5% of the total SSI cases. Conclusions The study found that the patients who received chlorhexidine–alcohol as skin antiseptic had less chance of developing SSI than those who received povidone–iodine; however, it did not reach a statistical significance. Trial registration Clinical Trials Registry of India CTRI/2018/05/014294. Registered on May 31, 2018

Chlorhexidine–Alcohol Compared with Povidone–Iodine Preoperative Skin Antisepsis for Cesarean Delivery: A Systematic Review and Meta-Analysis

2018 ◽  
Vol 36 (02) ◽  
pp. 118-123 ◽  
Author(s):  
Megan Whitham ◽  
Sherif El-Nashar ◽  
Steven Clark ◽  
Mary Tolcher
Keyword(s):  
Surgical Site Infection ◽  
Cesarean Delivery ◽  
Povidone Iodine ◽  
Meta Analysis ◽  
Site Infection ◽  
Superficial Infection ◽  
Skin Preparation ◽  
Statistical Heterogeneity ◽  
Significant Difference ◽  
Skin Antisepsis

Objective To compare chlorhexidine–alcohol with povidone–iodine solutions for skin antisepsis prior to cesarean delivery for the prevention of surgical site infection. Study Design Electronic databases MEDLINE, Embase, Scopus, and Clinicaltrials.gov were searched from inception to August 2017. Eligible studies included randomized controlled trials comparing chlorhexidine–alcohol with povidone–iodine skin preparation solutions for women undergoing cesarean delivery. The primary outcome was surgical site infection including superficial or deep wound infection. Meta-analysis was performed, and risk ratios (RRs) with 95% confidence interval (CI) were calculated using the Mantel–Haenszel random effects model. Statistical heterogeneity was assessed using Higgin's I 2. Results Of 61 abstracts identified in the primary search, four studies (3,059 women) met the eligibility criteria. The risk of surgical site infection was significantly reduced with chlorhexidine–alcohol (RR: 0.72; 95% CI: 0.52–0.98). No heterogeneity across studies was observed with I 2 = 0%. Subgroup analysis of superficial infection only or deep infection only showed no statistically significant difference (RR: 0.76, 95% CI: 0.54–1.08; and RR: 0.50, 95% CI: 0.23–1.10, respectively). Conclusion Preoperative skin cleansing prior to cesarean delivery with chlorhexidine–alcohol reduces surgical site infection as compared with povidone–iodine solutions.

Chlorhexidine-alcohol versus povidone-iodine as preoperative skin antisepsis for prevention of Surgical Site Infection in Cesarean Section

2021 ◽  
Author(s):  
Athokpam Lenin Luwang ◽  
Pradip Kumar Saha ◽  
Minakshi Rohilla ◽  
Pooja Sikka ◽  
lekha saha ◽  
...  
Keyword(s):  
Cesarean Section ◽  
Surgical Site Infection ◽  
Povidone Iodine ◽  
Statistical Significance ◽  
Site Infection ◽  
Exclusion Criteria ◽  
Skin Preparation ◽  
Alcohol Group ◽  
Post Operative Period ◽  
Skin Antisepsis

Abstract Objectives: To compare the efficacy of chlorhexidine-alcohol and povidone-iodine as preoperative antiseptic skin preparation for prevention of Surgical site infection(SSI) after Cesarean Section(CS).Materials and Methods: A total of 311 eligible women who underwent CS were recruited in the study after fulfilling all the inclusion and exclusion criteria. Patients were randomized into two groups (153 in Chlorhexidine-alcohol Group and 158 in povidone-iodine Group) by computer-generated randomization table. Patients were followed for a period of 30 days in post operative period to monitor for SSI.Results: The overall rate of SSI was 7%, out of which chlorhexidine-alcohol group had 5.4% and povidone-iodine group had 8.6%. E.coli, K.pneumoniae and Acinetobacter baumannii were the most common organism isolated. E.coli was found in 9.5% of the total SSI cases.Conclusions: The study found that the patients who received chlorhexidine-alcohol as skin antiseptic had less chance of developing SSI than those who received povidone iodine however it did not reach statistical significance.

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