Conversion of arsenobetaine to dimethylarsinic acid by arsenobetaine-decomposing bacteria isolated from coastal sediment

1991 ◽  
Vol 5 (5) ◽  
pp. 435-438 ◽  
Author(s):  
Ken'Ichi Hanaoka ◽  
Shoji Tagawa ◽  
Toshikazu Kaise
Keyword(s):  
Coastal Sediment ◽  
Dimethylarsinic Acid

Overview of Regional Coastal Sediment Processes and Controls

2003 ◽  
Author(s):  
Magnus Larson ◽  
Julie D. Rosati ◽  
Nicholas C. Kraus
Keyword(s):  
Coastal Sediment

scholarly journals Importance of monitoring arsenic methylation metabolism in acute promyelocytic leukemia patients receiving the treatment of arsenic trioxide

2021 ◽  
Vol 10 (1) ◽  
Author(s):  
Yu Zheng ◽  
Yuan-Fei Mao ◽  
Hui-Jin Zhao ◽  
Li Chen ◽  
Li-Ning Wang ◽  
...  
Keyword(s):  
Arsenic Trioxide ◽  
Acute Promyelocytic Leukemia ◽  
Arsenic Speciation ◽  
Promyelocytic Leukemia ◽  
Chronic Liver ◽  
Dimethylarsinic Acid ◽  
Metabolic Pattern ◽  
Methylation Index ◽  
Arsenic Methylation

Abstract Background Arsenic trioxide [ATO, inorganic arsenite (iAsIII) in solution] plays an important role in the treatment of acute promyelocytic leukemia (APL). However, the long-term adverse effects (AEs) and the retention of arsenic among APL patients are rarely reported. In this study, we focused on arsenic methylation metabolism and its relationship with chronic hepatic toxicity, as we previously reported, among APL patients who had finished the treatment of ATO. Methods A total of 112 de novo APL patients who had completed the ATO-containing treatment were enrolled in the study. Arsenic species [iAsIII, inorganic arsenate (iAsV), and their organic metabolites, monomethylarsonic acid (MMA) and dimethylarsinic acid (DMA)] in patients’ plasma, urine, hair and nails were detected by high-performance liquid chromatography combined with inductively coupled plasma mass spectrometry (HPLC-ICP-MS). Eighteen single nucleotide polymorphisms (SNPs) of the arsenic (+ 3 oxidative state) methylation transferase (AS3MT) gene, which was known as the main catalyzer for arsenic methylation, were tested with the polymerase chain reaction method. Results The study showed the metabolic pattern of arsenic in APL patients undergoing and after the treatment of ATO, in terms of total arsenic (TAs) and four species of arsenic. TAs decreased to normal after 6 months since cessation of ATO. But the arsenic speciation demonstrated significantly higher portion of iAsIII in patient’s urine (40.08% vs. 1.94%, P < 0.001), hair (29.25% vs. 13.29%, P = 0.002) and nails (30.21% vs. 13.64%, P = 0.003) than the healthy controls’, indicating a decreased capacity of arsenic methylation metabolism after the treatment of ATO. Urine primary methylation index (PMI) was significantly lower in patients with both chronic liver dysfunction (0.14 vs. 0.28, P = 0.047) and hepatic steatosis (0.19 vs. 0.3, P = 0.027), suggesting that insufficient methylation of arsenic might be related to chronic liver disorders. Two SNPs (A9749G and A27215G) of the AS3MT gene were associated with impaired urine secondary methylation index (SMI). Conclusions The long-term follow-up of arsenic speciation indicated a decreased arsenic methylation metabolism and a probable relationship with chronic hepatic disorders among APL patients after the cessation of ATO. Urine PMI could be a monitoring index for chronic AEs of ATO, and the SNPs of AS3MT gene should be considered when determining the dosage of ATO.

scholarly journals An Integrated Coastal Sediment Management Plan: The Example of the Tuscany Region (Italy)

2020 ◽  
Vol 8 (1) ◽  
pp. 33 ◽  
Author(s):  
Enzo Pranzini ◽  
Irene Cinelli ◽  
Luigi E. Cipriani ◽  
Giorgio Anfuso
Keyword(s):  
Stability Index ◽  
Management Plan ◽  
Sediment Management ◽  
Coastal Sediment ◽  
National Guidelines ◽  
Management Actions ◽  
Erosion Processes ◽  
Human Effects ◽  
Sufficient Magnitude ◽  
Sound Management

This paper presents the results of a study carried out to support the Region of Tuscany Coastal Sediment Management Plan, with the main aim of establishing the sediment budget considering the time span from 1981–1985 to 2005 for the 56 coastal sectors into which the 215 km-long continental sandy coast of Tuscany (Italy) was divided. The sand stability (according to a stability index) and colour compatibility (according to the CIEL*a*b* colour space with an acceptability range conforming to national guidelines) were determined in order to assess the possibility of using the available sediment in accreting sectors to nourish the beach in eroding areas. Only in two cases—i.e., the updrift of a harbour (at Viareggio) and in a convergence zone (at Marina di Pietrasanta)—are the volumes of sufficient magnitude to support a large nourishment project; however, the mean sand size is too small to guarantee efficient nourishment, even with medium-term stability. In contrast, the colour difference, in most of the cases, was shown to be acceptable. Other small sediment stocks, suitable for colour but not for grain size, can be used for periodic ephemeral nourishment works to support seasonal tourist activities. The limited resources available make it necessary to adopt a plan for their optimal use from a regional perspective. This kind of study is of great interest for the proposal of sound management actions to counteract the increasing erosion processes linked to climate change phenomena and human effects on rivers and coastal systems.

Contamination characteristics of siloxanes in coastal sediment collected from industrialized bays in South Korea

2019 ◽  
Vol 182 ◽  
pp. 109457
Author(s):  
Danbi Lee ◽  
Min-Kyu Park ◽  
In-Seok Lee ◽  
Sung-Deuk Choi
Keyword(s):  
South Korea ◽  
Coastal Sediment

Seasonal variations in the stable carbon isotopic signature of biogenic methane in a coastal sediment

Science ◽  
1986 ◽  
Vol 233 (4770) ◽  
pp. 1300-1303 ◽  
Author(s):  
C. Martens ◽  
N. Blair ◽  
C. Green ◽  
D. Des Marais
Keyword(s):  
Seasonal Variations ◽  
Isotopic Signature ◽  
Coastal Sediment ◽  
Stable Carbon ◽  
Biogenic Methane ◽  
Carbon Isotopic

Methylation of Arsenic by Freshwater Green Algae

1983 ◽  
Vol 40 (8) ◽  
pp. 1254-1257 ◽  
Author(s):  
M. D. Baker ◽  
P. T. S. Wong ◽  
Y. K. Chau ◽  
C. I. Mayfield ◽  
W. E. Inniss
Keyword(s):  
Green Algae ◽  
Lake Water ◽  
Sodium Arsenite ◽  
Basal Medium ◽  
Arsenic Species ◽  
Freshwater Ecosystems ◽  
Dimethylarsinic Acid ◽  
Additional Source ◽  
Arsenic Compounds ◽  
Methylarsonic Acid

Isolates from four genera of freshwater green algae were capable of methylating sodium arsenite in lake water and Bold's basal medium. Analysis of the liquid phase of the methylation flasks revealed the presence of methylarsonic acid, dimethylarsinic acid, and trimethylarsine oxide. Volatile arsine and methylarsines were not detected in the headspace gases presumably because of the inability of the algae to reduce completely the methylated–arsenic species. Although the algae varied with respect to their methylating abilities, the levels of methylated–arsenic compounds were always significantly higher when the algae were grown in lake water. This may have been due to the lower phosphate concentration in the lake water. We suggest that arsenic methylation by green algae constitutes an additional source for the formation and cycling of organo-arsenic compounds in freshwater ecosystems.

The Metazoan Meiofauna in Its Biogeochemical Environment: The Case of an Antarctic Coastal Sediment

1998 ◽  
Vol 78 (2) ◽  
pp. 411-434 ◽  
Author(s):  
S. Vanhove ◽  
H.J. Lee ◽  
M. Beghyn ◽  
D. Van Gansbeke ◽  
S. Brockington ◽  
...  
Keyword(s):  
Organic Matter ◽  
Standing Stock ◽  
Austral Summer ◽  
Fine Sand ◽  
Coastal Sediment ◽  
Feeding Guild ◽  
Fresh Organic Matter ◽  
Benthic Environment ◽  
Metazoan Meiofauna ◽  
Deposit Feeding

The metazoan meiobenthos was investigated in an Antarctic coastal sediment (Factory Cove, Signy Island, Antarctica). The fine sands contained much higher abundances compared to major sublittoral sediments worldwide. Classified second after Narrangansett Bay (North Atlantic) they reached numbers of 13 × 106ind m-2. The meiofauna was highly abundant in the surface layers, but densities decreased sharply below 2 cm. Vertical profiles mirrored steep gradients of microbiota, chloropigments and organic matter and were coincident with chemical stratification. Spatial patchiness manifested especially in the surface layer. Nematodes dominated (up to 90%), andAponema, Chromctdorita, Diplolaimella, Daptonema, MicrolaimusandNeochromadoraconstituted almost the entire community. Overall, the nematode fauna showed a strong similarity with fine sand communities elsewhere. The dominant trophic strategies were epistrarum and non-selective deposit feeding, but the applied classification for feeding guild structure of the nematodes of Factory Cove is discussed. High standing stock, low diversity and shallow depth distribution may have occurred because of the high nutritive (chlorophyll exceeded lOOOmgm-2and constituted almost 50% of the organic pool) and reductive character of the benthic environment. These observations must have originated from the substantial input of fresh organic matter from phytoplankton and microphytobenthic production, typical for an Antarctic coastal ecosystem during the austral summer.

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