Comparative chronic toxicity, including tumorigenicity, of gallium arsenide and arsenic trioxide intratracheally instilled into hamsters

1988 ◽  
Vol 2 (4) ◽  
pp. 333-337 ◽  
Author(s):  
Shiro Ohyama ◽  
Noburu Ishinishi ◽  
Akira Hisanaga ◽  
Akiyo Yamamoto
Keyword(s):  
Gallium Arsenide ◽  
Arsenic Trioxide ◽  
Chronic Toxicity

Vapor Phase Equilibria of Arsenic-Trioxide over Gallium Arsenide

1979 ◽  
Vol 18 (4) ◽  
pp. 723-728 ◽  
Author(s):  
Iwao Teramoto ◽  
Hiromitsu Takagi ◽  
Gota Kano
Keyword(s):  
Gallium Arsenide ◽  
Phase Equilibria ◽  
Arsenic Trioxide ◽  
Vapor Phase

scholarly journals Evaluation of chronic toxicity of Kushta Sammulfar (calx of Arsenic trioxide)

2013 ◽  
Vol 3 (1) ◽  
pp. 3
Author(s):  
Athar Parvez Ansari ◽  
Abdul Wadud ◽  
Najeeb Jahan ◽  
Renuka Bangalore Nagaraj ◽  
Shamim Irshad ◽  
...  
Keyword(s):  
Arsenic Trioxide ◽  
Chronic Toxicity ◽  
Safety Data ◽  
Dependent Manner ◽  
Test Drug ◽  
Unani Medicine ◽  
Group I ◽  
Kg Medium ◽  
Dose Levels ◽  
Dose Dependent

<em>Sammulfar</em> (arsenic trioxide) is a notorious poison and has extensively been studied for its toxicity. It is in use for various purposes for centuries and is used even today as a therapeutic agent in the form of <em>kushta</em> (calx) in traditional systems of medicine, particularly Unani medicine, but without apparent safety data. The present study, therefore, was conducted to produce data for prolong use of calx of arsenic trioxide. The calx (test drug) was prepared by the method described in National Formulary of Unani Medicine. The study was carried in healthy Wistar rats of either sex; weighing 150-250 g; 2-3 months of age, in a dose dependent manner, following the methods of Gupta et al. (2002), Ghosh (2008) and Klaassan (2008). The animals were divided into four groups of 10 animals each. Group I served as control, where as group II, III and IV were used for three dose levels of the test drug <em>i.e.</em> low (8.75 mg<sup>&ndash;1</sup> kg), medium (17.50 mg<sup>&ndash;1</sup> kg) and higher (26.25 mg<sup>&ndash;1</sup> kg). Standard parameters usually applied for chronic toxicity studies were considered. The study revealed dose dependent toxicity. Usual signs of chronic toxicity were observed during the study. Low dose of <em>Kushta Sammulfar </em>(KSF) did not produce remarkable toxic effects. Mild to moderate toxicity was seen in KSF-II and KSF-III.

Carcinogenicity and Chronic Toxicity of Para-Chloronitrobenzene in Rats and Mice by Two-Year Feeding

2006 ◽  
Vol 25 (3) ◽  
pp. 571-584 ◽  
Author(s):  
Michiharu Matsumoto ◽  
Shigetoshi Aiso ◽  
Hideki Senoh ◽  
Kazunori Yamazaki ◽  
Heihachiro Arito ◽  
...  
Keyword(s):  
Chronic Toxicity ◽  
Rats And Mice

Acute and chronic toxicity studies on Polygonum glabrum in experimental animals

2020 ◽  
Vol 3 (1) ◽  
pp. 7-10
Author(s):  
Saravanakumar A ◽  
Gandhimathi R
Keyword(s):  
Chronic Toxicity ◽  
Clinical Stage ◽  
Herbal Medicines ◽  
Plant Roots ◽  
Root Extract ◽  
Experimental Animals ◽  
Toxicity Studies ◽  
Acute And Chronic Toxicity ◽  
Diuretic Agents

Polygonum glabrum is being used in traditional and folklore medicine to treat pneumonia and jaundice. Plant roots are used in ayurvedic preparations to treat fever and colic. The leaves are used as diuretic agents and process vermifuge action. Plant decoction is also used in the treatment of Rheumatism. Besides having many uses and folklore claims, herbal medicines are to be thoroughly investigated for their toxicity also. Therefore this work is being carried out to examine the toxicity of the drug and established dose is safe to use in the clinical stage. The current research studied the acute and chronic toxicity of Polygonum glabrum root extract in rats. It is proved that there was no change in any parameter tested both in acute and chronic toxicity, which means the extract is safe and non-toxic at the dose of 2g/kg also.

EXPERIMENTAL VERIFICATION OF DLTS MODELS

2019 ◽  
Author(s):  
Nataliya Mitina ◽  
Vladimir Krylov
Keyword(s):  
Activation Energy ◽  
Gallium Arsenide ◽  
Data Processing ◽  
Experimental Verification ◽  
Deep Level ◽  
Deep Levels ◽  
Transient Spectroscopy

The results of an experiment to determine the activation energy of a deep level in a gallium arsenide mesastructure, obtained by the method of capacitive deep levels transient spectroscopy with data processing according to the Oreshkin model and Lang model, are considered.

DEEP LEVELS' ACTIVATION ENERGY DEPENDENCE ON MEASUREMENT MODES

2019 ◽  
Author(s):  
Aleksey Bogachev ◽  
Vladimir Krylov
Keyword(s):  
Activation Energy ◽  
Gallium Arsenide ◽  
Energy Dependence ◽  
Deep Level ◽  
Deep Levels ◽  
Blocking Voltage

The results of an experiment to determine the activation energy of a deep level in a gallium arsenide mesastructure by capacitive relaxation spectroscopy of deep levels at various values of the blocking voltage are considered.

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