Retracted : A new class of copper(I) complexes with imine‐containing chelators which show potent anticancer activity

2020 ◽  
Vol 34 (4) ◽  
Author(s):  
Neda Choodari Milani ◽  
Yazdan Maghsoud ◽  
Mahdieh Hosseini ◽  
Abouzar Babaei ◽  
Hamidreza Rahmani ◽  
...  
Keyword(s):  
Anticancer Activity ◽  
New Class

scholarly journals A new class of platinum(ii) complexes with the phosphine ligand pta which show potent anticancer activity

2018 ◽  
Vol 5 (1) ◽  
pp. 39-53 ◽  
Author(s):  
M. D. Živković ◽  
J. Kljun ◽  
T. Ilic-Tomic ◽  
A. Pavic ◽  
A. Veselinović ◽  
...  
Keyword(s):  
Anticancer Activity ◽  
Phosphine Ligand ◽  
Phosphine Ligands ◽  
New Class

A series of 16 Pt(ii) complexes with 8-hydroxyquinolines and sulfoxide/phosphine ligands were synthetized, characterized and evaluated for cytotoxic and embryotoxic activity.

Synthesis, DNA binding affinity and anticancer activity of novel 4H-benzo[g][1,2,3]triazolo[5,1-c][1,4]oxazocines

2016 ◽  
Vol 14 (39) ◽  
pp. 9294-9305 ◽  
Author(s):  
K. N. Visweswara Sastry ◽  
Sunitha Rani Routhu ◽  
Soma Gupta Datta ◽  
Narayana Nagesh ◽  
Bathini Nagendra Babu ◽  
...  
Keyword(s):  
Dna Binding ◽  
Anticancer Activity ◽  
Binding Affinity ◽  
Cancer Therapeutics ◽  
New Class ◽  
Dna Binding Affinity

Cancer therapeutics: a new class of anticancer heterocycles was synthesized.

Synthesis, characterization, optical and electrochemical properties and antifungal and anticancer activities of ferrocenyl conjugated novel dendrimers

2017 ◽  
Vol 41 (4) ◽  
pp. 1714-1722 ◽  
Author(s):  
Velautham Saravanan ◽  
Ayyavoo Kannan ◽  
Perumal Rajakumar
Keyword(s):  
Antifungal Activity ◽  
Electrochemical Properties ◽  
Anticancer Activity ◽  
Click Chemistry ◽  
Fungal Pathogens ◽  
Anticancer Activities ◽  
New Class ◽  
Mcf 7

A new class of triazoloferrocenyl conjugates was prepared by copper(i) catalyzed click chemistry, which shows good antifungal activity against fungal pathogens, and also shows excellent anticancer activity against MCF-7 cells.

Design, Synthesis and In Vitro Anticancer Activity of a New Class of Bifunctional DNA Intercalators

2010 ◽  
Vol 7 (9) ◽  
pp. 644-649 ◽  
Author(s):  
Ana Maria V. Zbancioc ◽  
Gheorghita N. Zbancioc ◽  
Catalin Tanase ◽  
Anca Miron ◽  
Cornelia Ursu ◽  
...  
Keyword(s):  
Anticancer Activity ◽  
Design Synthesis ◽  
Dna Intercalators ◽  
New Class

ChemInform Abstract: Synthesis and Anticancer Activity of a New Class of Heterocyclic Compounds.

ChemInform ◽  
2010 ◽  
Vol 26 (47) ◽  
pp. no-no
Author(s):  
R. G. GLUSHKOV ◽  
O. S. SIZOVA ◽  
G. A. MODNIKOVA ◽  
A. S. SOKOLOVA ◽  
V. A. CHERNOV
Keyword(s):  
Anticancer Activity ◽  
Heterocyclic Compounds ◽  
New Class

Synthesis and In-silico identification of new bioactive 1,3,4-oxadiazole tagged 2,3-dihydroimidazo[1,2-a]pyridine derivatives

2020 ◽  
Vol 16 ◽  
Author(s):  
Bhagwat S. Jadhav ◽  
Vipul P. Purohit ◽  
Ramesh S. Yamgar ◽  
Rajesh S. Kenny ◽  
Suraj N. Mali ◽  
...  
Keyword(s):  
Molecular Docking ◽  
Anticancer Activity ◽  
In Silico ◽  
Antitubercular Activity ◽  
Docking Studies ◽  
Pyridine Derivatives ◽  
Molecular Docking Studies ◽  
New Class ◽  
In Silico Molecular Docking

Background: Tuberculosis (TB) continues to be the most threatening cause of death in recent years. There is urgent need of search more potent, less toxic antitubercular agents. Methods: A set of five new 1,3,4-oxadiazolyl-imidazo-1,2-pyridine derivatives (4a-4e) was synthesized and screened invitro for their antibacterial activity against Mycobacterium tuberculosis (H37 RV strain) ATCC No-27294. Results: Compound 4b displayed potent antitubercular activity at MIC 6.25 µg/mL. In-silico molecular docking studies were performed for evaluation of the binding patterns of compounds 4a-4e in the binding site of proteins like, Pantothenate synthatase and enoyl acyl reductase inhibitor. The outcomes of the in- vitro antitubercular studies were in well agreement with the molecular docking studies. These newly synthesized compounds were found to have good ADMET profile. We also explored possible anticancer activity using in-silico methods. Conclusion: These results shows that readily synthesized 1,3,4-oxadiazolyl-imidazo-1,2-pyridine derivatives (4a-4e) are attracting new class of potent anti-TB targets as well as possible anticancer activity that worth additional opportunities for improvements.

Recent Developments in Anticancer Activity of Compounds Containing the Thioether Group

2020 ◽  
Vol 20 ◽  
Author(s):  
Muhammad İ. Han ◽  
Şükriye G. Küçükgüzel
Keyword(s):  
Anticancer Activity ◽  
Anticancer Agents ◽  
Research Field ◽  
Cancer Development ◽  
Anticancer Activities ◽  
Cancer Disease ◽  
New Class ◽  
Research Activities ◽  
Recent Developments ◽  
Patent Literature

Background: Spreading rapidly in recent years, cancer has become the cause of one of the highest mortality rates after cardiovascular diseases. With more attention being directed to cancer, anticancer research has become an important research field. In spite of enormous research activities in this area, the reason for cancer development is still not clearly understood. Scientists are now working on the biology of cancer, especially on the root of the cause for cancer development. The aim is to treat the cancer disease, and thus cure the patients. Continuing efforts on the development of novel molecules as potential anticancer agents is essential for this purpose. Objective: The main aim of this review was to present a survey on the medicinal chemistry of thioethers and to provide practical data on their cytotoxicities against various cancer cell lines. Methods: Research articles published between 2001-2019 were consulted in the preparation of this review article though patent literature was not included here. Results: Compounds containing thioether functionality were proven to have anticancer activities. Indeed, thioether functionality was found to be a must in some cases to show anticancer activity. Conclusion: Thioether containing molecules may emerge as new class of potent and effective anticancer agents in the near future.

Sign in / Sign up

Export Citation Format

Share Document