A combined experimental and modelling investigations on mixed bioligand complexes of divalent cobalt and copper in β ‐cyclodextrin

2019 ◽  
Vol 34 (1) ◽  
Author(s):  
M.S.A. Abdel‐Mottaleb ◽  
E.H. Ismail
Keyword(s):  
Divalent Cobalt

On The EPR Parameters of Divalent Cobalt in ZnX (X = S, Se, Te) And CdTe

2004 ◽  
Vol 59 (12) ◽  
pp. 938-942 ◽  
Author(s):  
Shao-Yi Wu ◽  
Hui-Ning Dong
Keyword(s):  
Electron Paramagnetic Resonance ◽  
Charge Transfer ◽  
Spin Orbit Coupling ◽  
Spin Orbit ◽  
Paramagnetic Resonance ◽  
A Value ◽  
Epr Parameters ◽  
Divalent Cobalt ◽  
Structure Constants ◽  
Electron Paramagnetic

The electron paramagnetic resonance (EPR) parameters g and the hyperfine structure constants A of Co2+ in ZnX (X = S, Se, Te) and CdTe are studied, using the perturbation formulas of the EPR parameters for a 3d7 ion in tetrahedra based on two mechanism models. In these formulas, both the contributions from the conventional crystal-field (CF) mechanism and those from the charge-transfer (CT) mechanism are taken into account. According to the investigations, the sign of the g-shift ΔgCT from the CT mechanism is the same as ΔgCF from the CF mechanism, whereas the contributions to the A value from the CF and CT mechanisms have opposite signs. Particularly, the contributions to the EPR parameters from the CT mechanism increase rapidly with increase of the spin-orbit coupling coefficient of the ligand and the covalency effect of the systems, i. e. S2− < Se2− < Te2−.

scholarly journals Research Strategies in the Study of the Pro-Oxidant Nature of Polyphenol Nutraceuticals

2011 ◽  
Vol 2011 ◽  
pp. 1-12 ◽  
Author(s):  
Harvey Babich ◽  
Alyssa G. Schuck ◽  
Jeffrey H. Weisburg ◽  
Harriet L. Zuckerbraun
Keyword(s):  
Oxidative Stress ◽  
Reactive Oxygen Species ◽  
Lipid Peroxidation ◽  
Copper Ions ◽  
Oxygen Species ◽  
Research Strategies ◽  
Dual Nature ◽  
Intracellular Glutathione ◽  
Divalent Cobalt ◽  
Per Se

Polyphenols of phytochemicals are thought to exhibit chemopreventive effects against cancer. These plant-derived antioxidant polyphenols have a dual nature, also acting as pro-oxidants, generating reactive oxygen species (ROS), and causing oxidative stress. When studying the overall cytotoxicity of polyphenols, research strategies need to distinguish the cytotoxic component derived from the polyphenolper sefrom that derived from the generated ROS. Such strategies include (a) identifying hallmarks of oxidative damage, such as depletion of intracellular glutathione and lipid peroxidation, (b) classical manipulations, such as polyphenol exposures in the absence and presence of antioxidant enzymes (i.e., catalase and superoxide dismutase) and of antioxidants (e.g., glutathione andN-acetylcysteine) and cotreatments with glutathione depleters, and (c) more recent manipulations, such as divalent cobalt and pyruvate to scavenge ROS. Attention also must be directed to the influence of iron and copper ions and to the level of polyphenols, which mediate oxidative stress.

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