Synthesis, characterization, spectroscopic and theoretical studies of transition metal complexes of new nano Schiff base derived from l -histidine and 2-acetylferrocene and evaluation of biological and anticancer activities

2018 ◽  
Vol 32 (7) ◽  
pp. e4386 ◽  
Author(s):  
Walaa H. Mahmoud ◽  
M.M. Omar ◽  
Fatma N. Sayed ◽  
Gehad G. Mohamed
Keyword(s):  
Schiff Base ◽  
Transition Metal ◽  
Metal Complexes ◽  
Transition Metal Complexes ◽  
Theoretical Studies ◽  
Anticancer Activities

scholarly journals Heterocyclic Schiff base transition metal complexes in antimicrobial and anticancer chemotherapy

MedChemComm ◽  
2018 ◽  
Vol 9 (3) ◽  
pp. 409-436 ◽  
Author(s):  
Manzoor Ahmad Malik ◽  
Ovas Ahmad Dar ◽  
Parveez Gull ◽  
Mohmmad Younus Wani ◽  
Athar Adil Hashmi
Keyword(s):  
Schiff Base ◽  
Transition Metal ◽  
Metal Complexes ◽  
Transition Metal Complexes ◽  
Anticancer Activities ◽  
Anticancer Chemotherapy ◽  
Base Transition

Schiff-base transition metal complexes display amazing antimicrobial and anticancer activities.

Synthesis, Characterization and in vitro Biological Evaluation of a New Schiff Base Derived from Drug and its Complexes with Transition Metal Ions

2018 ◽  
Vol 69 (7) ◽  
pp. 1678-1681
Author(s):  
Amina Mumtaz ◽  
Tariq Mahmud ◽  
M. R. J. Elsegood ◽  
G. W. Weaver
Keyword(s):  
Schiff Base ◽  
Transition Metal ◽  
Metal Ions ◽  
Metal Complexes ◽  
Transition Metal Complexes ◽  
Free Ligand ◽  
Transition Metal Ions ◽  
Biological Evaluation ◽  
Pyridoxal Hydrochloride

New series of copper (II), cobalt (II), zinc (II), nickel (II), manganese (II), iron (II) complexes of a novel Schiff base were prepared by the condensation of sulphadizine and pyridoxal hydrochloride. The ligand and metal complexes were characterized by utilizing different instrumental procedures like microanalysis, thermogravimetric examination and spectroscopy. The integrated ligand and transition metal complexes were screened against various bacteria and fungus. The studies demonstrated the enhanced activity of metal complexes against reported microbes when compared with free ligand.

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