Interaction of Amino Acid Schiff Base Metal Complexes with DNA/BSA Protein and Antibacterial Activity: Spectral Studies, DFT Calculations and Molecular Docking Simulations

2018 ◽  
Vol 32 (4) ◽  
pp. e4259 ◽  
Author(s):  
M.A. Neelakantan ◽  
K. Balamurugan ◽  
Chithiraivel Balakrishnan ◽  
L. Subha
Keyword(s):  
Antibacterial Activity ◽  
Schiff Base ◽  
Molecular Docking ◽  
Amino Acid ◽  
Dft Calculations ◽  
Metal Complexes ◽  
Spectral Studies ◽  
Docking Simulations ◽  
Schiff Base Metal Complexes ◽  
Amino Acid Schiff Base

SPI/CS nanoparticles conjugating amino acid Schiff-base metal complexes for mimic of SOD

2017 ◽  
Vol 259 ◽  
pp. e182-e183
Author(s):  
Yufeng He ◽  
Guifang Yan ◽  
Zhili Xu ◽  
Jianfeng Wang ◽  
Wenzhen Qian ◽  
...  
Keyword(s):  
Schiff Base ◽  
Amino Acid ◽  
Metal Complexes ◽  
Base Metal ◽  
Schiff Base Metal Complexes ◽  
Amino Acid Schiff Base

Schiff base metal complexes: Synthesis, characterization, thermal analysis and antibacterial activity

2020 ◽  
Vol 13 (4) ◽  
pp. 265
Author(s):  
Tuly Paul ◽  
Md. Faruk Hossen ◽  
Md. Kudrat-E-Zahan ◽  
Md. Masuqul Haque ◽  
Md. Saddam Hossain ◽  
...  
Keyword(s):  
Thermal Analysis ◽  
Antibacterial Activity ◽  
Schiff Base ◽  
Metal Complexes ◽  
Base Metal ◽  
Schiff Base Metal Complexes

scholarly journals Synthesis, Characterization and Electrochemical Sensor Based Upon Novel Schiff Base Metal Complexes Derived from the Non-Steroidal Anti-inflammatory Drug, Flufenamic Acid for the Determination of Uric acid and their Biological Applications

2020 ◽  
Vol 11 (4) ◽  
pp. 11390-11403
Keyword(s):  
Uric Acid ◽  
Schiff Base ◽  
Metal Complexes ◽  
Base Metal ◽  
Schiff Base Ligand ◽  
Flufenamic Acid ◽  
Spectral Studies ◽  
Anti Inflammatory ◽  
Schiff Base Metal Complexes

The current trend in coordination chemistry is the design and synthesis of new Schiff base transition metal complexes for therapeutic, diagnostic, and catalytic applications. For decades, it has been observed that special attention is being paid to the chemistry of Schiff base metal complexes because of their wide range of applications. Therefore the present paper involves the synthesis of Schiff base ligand by altering the functional group of the drug, Flufenamic acid. From that Schiff base ligand, four complexes, i.e., Co(II), Cu(II), Ni(II), and Zn(II) have been prepared (SB metal complexes). The synthesized SB metal complexes have been characterized using several spectral and analytical techniques. All the metal complexes show non-electrolytic behavior suggested by molar conductance measurements. Spectral studies suggest that all four metal complexes exhibit octahedral geometry. The modified SB-Co complex/GCE showed a greater electro-catalytic activity and lower potential towards the oxidation of uric acid (UA). The response of UA was linear over the concentration ranging from CV is 0.5–1.8 μmol/L, sensitivity for 131.85 μAμM-1cm-2, and detection limit for 0.16 μM (S/N=3). The modified GCE showed very good sensitivity along with good repeatability and reproducibility for the determination of UA. The pure drug, Schiff base ligand, and metal complexes, were also screened for anti-inflammatory and antibacterial activities. The observed results prove that the metal complexes exhibit greater activity than that of the original drug.

scholarly journals Synthesis, characterization and antibacterial activity studies of new 2-pyrral-L-amino acid Schiff base palladium (II) complexes

2020 ◽  
Vol 74 (11) ◽  
pp. 3705-3715 ◽  
Author(s):  
Eunice A. Nyawade ◽  
Martin O. Onani ◽  
Samantha Meyer ◽  
Phumuzile Dube
Keyword(s):  
Antibacterial Activity ◽  
Schiff Base ◽  
Amino Acid ◽  
Amino Acid Schiff Base
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