Sulfonic acid supported on magnetic nanoparticle as an eco-friendly, durable and robust catalyst for the synthesis of β-amino carbonyl compounds through solvent free Mannich reaction

2017 ◽  
Vol 31 (12) ◽  
pp. e3865 ◽  
Author(s):  
Farhad Kabiri Esfahani ◽  
Daryoush Zareyee ◽  
Ali Shokuhi Rad ◽  
Sima Taher-Bahrami
Keyword(s):  
Mannich Reaction ◽  
Carbonyl Compounds ◽  
Sulfonic Acid ◽  
Magnetic Nanoparticle ◽  
Solvent Free

A Novel Environment Friendly Material: Sucrose Char Sulfonic Acid Catalyzed Three-Component Mannich Reaction

2014 ◽  
Vol 989-994 ◽  
pp. 134-137
Author(s):  
Yuan Yuan She ◽  
Xuan Yan Liu ◽  
Zhi Gao Yang
Keyword(s):  
Mannich Reaction ◽  
Carbonyl Compounds ◽  
Sulfonic Acid ◽  
Aromatic Aldehydes ◽  
Reaction Conditions ◽  
One Pot ◽  
Environment Friendly ◽  
Novel Environment ◽  
Acid Catalyzed ◽  
The One

Sucrose char sulfonic acid (SCSA) efficiently catalyzed the one-pot, three-component Mannich reaction of ketones, aromatic aldehydes and different amines in ethanol at 30°C and afforded the corresponding β-amino carbonyl compounds in good to excellent yields . This method provides a novel and improved modification of the three-component Mannich reaction in terms of mild reaction conditions , clean reaction profiles and a simple workup procedure.

scholarly journals Magnetic nanoparticle-supported sulfonic acid as a green catalyst for the one-pot synthesis of 2,4,5-trisubstituted imidazoles and 1,2,4,5-tetrasubstituted imidazoles under solvent-free conditions

2021 ◽  
Vol 27 (1) ◽  
pp. 71-78
Author(s):  
Mahnaz Sakhdari ◽  
Ali Amoozadeh ◽  
Eskandar Kolvari
Keyword(s):  
High Purity ◽  
Sulfonic Acid ◽  
Magnetic Nanoparticle ◽  
Solvent Free ◽  
High Catalytic Activity ◽  
One Pot ◽  
Efficient Catalyst ◽  
Solvent Free Conditions ◽  
The One ◽  
Tetrasubstituted Imidazoles

Abstract In this work, magnetic nanoparticle-supported sulfonic acid (γ-Fe2O3-SO3H) is used as an efficient catalyst in the synthesis of 2,4,5-trisubstituted imidazoles and 1,2,4,5-tetrasubstituted imidazoles in a short time (40–70 min for trisubstituted imidazoles and 30–40 min for tetrasubstituted imidazoles) and high-purity products were obtained (92–98% for trisubstituted imidazoles and 94–98% for tetrasubstituted imidazoles) in simple multicomponent reactions. The structure of these products was confirmed via FT-IR and NMR. Green and recyclable catalysts, eco-friendly and solvent-free conditions, high catalytic activity, shorter reaction time, easy recovery by an external magnet, high purity, and excellent yields are some features of these reactions.

One-Pot, Regioselective Synthesis of Homopropargyl Alcohols using Propargyl Bromide and Carbonyl Compound by the Mg-mediated Reaction under Solvent-free Conditions

2020 ◽  
Vol 17 (6) ◽  
pp. 438-442
Author(s):  
Xiaofang Ma ◽  
Shunxi Li ◽  
Samrat Devaramani ◽  
Guohu Zhao ◽  
Daqian Xu
Keyword(s):  
Reaction Time ◽  
Organic Synthesis ◽  
Carbonyl Compounds ◽  
Solvent Free ◽  
Propargyl Bromide ◽  
Important Goal ◽  
One Pot ◽  
Short Reaction Time ◽  
Solvent Free Conditions ◽  
Volatile Organic

The elimination of volatile organic solvents in organic synthesis is the most important goal in “Green” chemistry. We report a simple, efficient and facile method for the addition of progargyl bromide to carbonyl compounds using Mg metal as a mediator under solvent-free conditions which could regioselectively generate homopropargyl alcohols efficiently in good to excellent yields. The procedure has advantages such as short reaction time, operationally simple, excellent product yields, high regioselectivity and organic solvent-free.

Solvent‐Free Single‐Pot Mannich Reaction and Detoxification of Industrial Hazardous Waste Methyl Mercaptan Gas

2021 ◽  
Vol 6 (5) ◽  
pp. 1088-1092
Author(s):  
Sharada Prasanna Swain ◽  
Nagendra Prasad ◽  
Latchi Reddy ◽  
G. Subrahmanyam ◽  
Sandeep Mohanty
Keyword(s):  
Hazardous Waste ◽  
Mannich Reaction ◽  
Solvent Free ◽  
Methyl Mercaptan
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