Iron oxide nanoparticles coated with green tea extract as a novel magnetite reductant and stabilizer sorbent for silver ions: Synthetic application of Fe3O4@green tea/Ag nanoparticles as magnetically separable and reusable nanocatalyst for reduction of 4-

2017 ◽  
Vol 31 (10) ◽  
pp. e3711 ◽  
Author(s):  
Hojat Veisi ◽  
Fatemeh Ghorbani
Keyword(s):  
Iron Oxide ◽  
Iron Oxide Nanoparticles ◽  
Green Tea ◽  
Ag Nanoparticles ◽  
Silver Ions ◽  
Green Tea Extract ◽  
Oxide Nanoparticles ◽  
Magnetically Separable ◽  
Tea Extract ◽  
Synthetic Application

Iron Oxide Nanoparticles Synthesized via Green Tea Extract for Doxorubicin Delivery

2020 ◽  
Vol 16 ◽  
Author(s):  
Lei Nie ◽  
Chenlei Cai ◽  
Meng Sun ◽  
Fang Zhang ◽  
Lingyun Zheng ◽  
...  
Keyword(s):  
Iron Oxide ◽  
Citric Acid ◽  
Iron Oxide Nanoparticles ◽  
Green Tea ◽  
Drug Carrier ◽  
Green Tea Extract ◽  
Cancer Drug ◽  
Control Group ◽  
Oxide Nanoparticles ◽  
Tea Extract

Background:: Due to the limitation of conventional cancer treatment using chemotherapy, the nanoparticle therapeutics showed enhanced efficacy with alleviating side effects. Objective:: The superparamagnetic iron oxide nanoparticles (T-C-SPION) would be prepared for doxorubicin (DOX) loading and delivery. Methods:: Here, we reported a simple green strategy to fabricate T-C-SPION using green tea extract and citric acid. Also, the anti-cancer drug, DOX, was used as a model drug to fabricate DOX-loaded nanoparticles. Results:: The formed T-C-SPION nanoparticles were spherical with a diameter of 23.8 ± 0.8 nm, confirmed by Transmission Electron Microscopy (TEM). Besides, Dynamic Light Scattering (DLS) revealed that the prepared nanoparticles were water-dispersible and stable while stored in water for 6 weeks. The CCK-8 assay showed that T-C-SPION had a good cytocompatibility using different iron concentrations (10 ~ 120 ug/mL). Furthermore, T-C-SPION had a higher DOX encapsulation efficiency (Eencaps), around 43.2 ± 1.8 %, which resulted in a lagged release profile of DOX, compared to other types of iron oxide nanoparticles using green tea or citric acid alone. Next, cell viability assay indicated that T-C-SPION with a higher Eencaps showed superior and sustained cytotoxicity compared to the control group. Conclusion:: The developed iron oxide nanoparticles synthesized by green tea extract and citric acid in this paper could be considered as a potential drug carrier for cancer therapy applications.

scholarly journals Iron and Iron Oxide Nanoparticles Synthesized with Green Tea Extract: Differences in Ecotoxicological Profile and Ability To Degrade Malachite Green

2018 ◽  
Vol 6 (7) ◽  
pp. 8679-8687 ◽  
Author(s):  
Pavla Plachtová ◽  
Zdenka Medříková ◽  
Radek Zbořil ◽  
Jiří Tuček ◽  
Rajender S. Varma ◽  
...  
Keyword(s):  
Iron Oxide ◽  
Iron Oxide Nanoparticles ◽  
Green Tea ◽  
Malachite Green ◽  
Green Tea Extract ◽  
Oxide Nanoparticles ◽  
Tea Extract

The Interaction of Zinc Oxide/Green Tea Extract Complex Nanoparticles and its Effect on Monosodium Glutamate Toxicity in Liver of Rats

2019 ◽  
Vol 20 (6) ◽  
pp. 465-475 ◽  
Author(s):  
Fawziah A. Al-Salmi ◽  
Reham Z. Hamza ◽  
Nahla S. El-Shenawy
Keyword(s):  
Oxidative Stress ◽  
Zinc Oxide ◽  
Green Tea ◽  
Zinc Oxide Nanoparticles ◽  
Monosodium Glutamate ◽  
Green Tea Extract ◽  
Control Group ◽  
Oxide Nanoparticles ◽  
Zno Nps ◽  
Tea Extract

Background: Zinc oxide nanoparticles (ZnO NPs) are increasingly utilized in both industrial and medical applications. Therefore, the study was aimed to investigate the effect of green nanoparticle complex (green tea extract/zinc oxide nanoparticles complex, GTE/ZnO NPs) on oxidative stress induced by monosodium glutamate (MSG) on the liver of rats. Methods: Wistar male rats (n=64) weighing between 200-250 g were divided randomly into eight groups: control group was given physiological saline (1 mg/kg), two groups were treated with two different doses of MSG (MSG-LD, MSG-HD; 6 and 17.5 mg/Kg, respectively), GTE was given 1 mg/mL, 5th group was treated with ZnO NPs and 6th group was treated with GTE/ZnO NPs complex while, 7th and 8th groups were treated with MSG-LD + GTE/ZnO NPs complex and MSG-HD + GTE/ZnO NPs complex, respectively. All substances were given orally for 30 consecutive days. At the end of the study, the liver was homogenized for measurement of the oxidative stress status and anti-inflammatory biomarkers as well as histological and transmission alternations. Results: Results showed that the antioxidant enzymes activity and glutathione level were significantly decreased in MSG groups than control in a dose-dependent manner. Conversely, the malondialdehyde and inflammatory cytokines levels were significantly increased in MSG groups than the control group. The liver indicated no evidence of alteration in oxidative status, anti-inflammatory and morphological parameters in GTE, ZnO NPs and GTE/ZnO NPs complex groups. Conclusion: In conclusion, MSG at both doses caused oxidative stress and inflammation on liver after 28 days of exposure that supported histological analysis and transmission view of hepatic parenchyma. GTE/ZnO NPs act as partial hepato-protective against MSG.

scholarly journals Cardioprotective Effect of Zinc Oxide Nanoparticles/Green Tea Extract Complex on Monosodium Glutamate Toxicity

2019 ◽  
pp. 1-5
Author(s):  
Nahla S. El-Shenawy ◽  
Reham Z. Hamza ◽  
Fawziah A. Al-Salmi
Keyword(s):  
Zinc Oxide ◽  
Body Weight ◽  
Green Tea ◽  
Zinc Oxide Nanoparticles ◽  
Monosodium Glutamate ◽  
Heart Tissue ◽  
Green Tea Extract ◽  
Oxide Nanoparticles ◽  
Zno Nps ◽  
Tea Extract

Monosodium glutamate (MSG) is used worldwide as a food additive, the survey has disclosed some of MSG's deleterious effects on various organs and tissues of rats. This research was achieved to determine the impact of MSG on the albino rats' antioxidant and histology of cardiac tissue. 48 male rats were divided into six groups of eight rats each. Group one used for monitoring and normal saline, whereas rats of group two were given the lower dosage of MSG 6 mg/Kg, rats in group three received 17.5 m/kg body weight of MSG, while rats in group four were given 10 mg/kg body weight of zinc oxide nanoparticles /green tea extract (ZnO NPs/GTE) complex, the fifth and sixth groups were treated with the lower and the higher doses of MSG with ZnO NP/GTE complex for 30 days. Each animal was sacrificed at the end of the treatment period and the heart was thoroughly separated, determining the antioxidant parameter and the histopathological changes. MSG administration to the rats has shown a substantial rise in peroxidation of cardiac heart tissue, decline in the activities of catalase, superoxide dismutase, and glutathione peroxidase beside the decrease in the glutathione level as compared to those in the control animals. The treatment the induced-rats with MSG using complex showed some degree of recovery by a reduction in LPO of the heart and enhancement of antioxidant enzymes. The findings suggested that the intrinsic antioxidant of the heart tissue can significantly be alternated with the use of MSG in a dose-dependent manner and these changes could be improved by using the green ZnO NPs complex. This complex acts as a factor to decrease the histological damage that could be happening by the induction of MSG.

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