Transfer hydrogenation of aryl ketones with homogeneous ruthenium catalysts containing diazafluorene ligands

2016 ◽  
Vol 30 (12) ◽  
pp. 1030-1035 ◽  
Author(s):  
Mehmet Fırat Baran ◽  
Feyyaz Durap ◽  
Murat Aydemir ◽  
Akın Baysal
Keyword(s):  
Ruthenium Catalysts ◽  
Transfer Hydrogenation ◽  
Aryl Ketones

scholarly journals Design of Iridium N-Heterocyclic Carbene Amino Acid Catalysts for Asymmetric Transfer Hydrogenation of Aryl Ketones

Catalysts ◽  
2021 ◽  
Vol 11 (6) ◽  
pp. 671
Author(s):  
Chad M. Bernier ◽  
Joseph S. Merola
Keyword(s):  
Amino Acids ◽  
Amino Acid ◽  
Enantiomeric Excess ◽  
Transfer Hydrogenation ◽  
Acid Catalysts ◽  
Asymmetric Transfer Hydrogenation ◽  
Reaction Conditions ◽  
Chiral Complexes ◽  
Acetophenone Derivatives ◽  
Aryl Ketones

A series of chiral complexes of the form Ir(NHC)2(aa)(H)(X) (NHC = N-heterocyclic carbene, aa = chelated amino acid, X = halide) was synthesized by oxidative addition of -amino acids to iridium(I) bis-NHC compounds and screened for asymmetric transfer hydrogenation of ketones. Following optimization of the reaction conditions, NHC, and amino acid ligands, high enantioselectivity was achieved when employing the Ir(IMe)2(l-Pro)(H)(I) catalyst (IMe = 1,3-dimethylimidazol-2-ylidene), which asymmetrically reduces a range of acetophenone derivatives in up to 95% enantiomeric excess.

ChemInform Abstract: 8-Amino-5,6,7,8-tetrahydroquinolines as Ligands in Iridium(III) Catalysts for the Reduction of Aryl Ketones by Asymmetric Transfer Hydrogenation (ATH).

ChemInform ◽  
2015 ◽  
Vol 46 (4) ◽  
pp. no-no
Author(s):  
Daniele Zerla ◽  
Giorgio Facchetti ◽  
Marco Fuse ◽  
Michela Pellizzoni ◽  
Carlo Castellano ◽  
...  
Keyword(s):  
Transfer Hydrogenation ◽  
Asymmetric Transfer Hydrogenation ◽  
Aryl Ketones

Highly Productive CNN Pincer Ruthenium Catalysts for the Asymmetric Reduction of Alkyl Aryl Ketones

2009 ◽  
Vol 15 (3) ◽  
pp. 726-732 ◽  
Author(s):  
Walter Baratta ◽  
Giorgio Chelucci ◽  
Santo Magnolia ◽  
Katia Siega ◽  
Pierluigi Rigo
Keyword(s):  
Asymmetric Reduction ◽  
Ruthenium Catalysts ◽  
Alkyl Aryl ◽  
Aryl Ketones
Sign in / Sign up

Export Citation Format

Share Document