scholarly journals Complementary approach for analysis of phospholipids by liquid chromatography hyphenated to elemental and molecular mass spectrometry

2020 ◽  
Author(s):  
Christian Vosse ◽  
Georgina M. Thyssen ◽  
Michael Sperling ◽  
Uwe Karst ◽  
Heiko Hayen
Keyword(s):  
Mass Spectrometry ◽  
Liquid Chromatography ◽  
Molecular Mass ◽  
Complementary Approach ◽  
Molecular Mass Spectrometry

Liquid chromatography combined with atomic and molecular mass spectrometry for speciation of arsenic in chicken liver

2014 ◽  
Vol 1370 ◽  
pp. 40-49 ◽  
Author(s):  
Hanyong Peng ◽  
Bin Hu ◽  
Qingqing Liu ◽  
Zonglin Yang ◽  
Xiufen Lu ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Liquid Chromatography ◽  
Molecular Mass ◽  
Chicken Liver ◽  
Molecular Mass Spectrometry

Use of molecular mass spectrometry in studying composition of dispersion media in lubricating greases

1978 ◽  
Vol 14 (9) ◽  
pp. 699-702
Author(s):  
L. N. Sosulina ◽  
L. I. Nazarova ◽  
E. M. Nikonorov ◽  
T. G. Zubkevich
Keyword(s):  
Mass Spectrometry ◽  
Molecular Mass ◽  
Molecular Mass Spectrometry ◽  
Dispersion Media

Use of elemental and molecular-mass spectrometry to assess the toxicological effects of inorganic mercury in the mouse Mus musculus

2014 ◽  
Vol 406 (24) ◽  
pp. 5853-5865 ◽  
Author(s):  
Miguel Ángel García-Sevillano ◽  
Tamara García-Barrera ◽  
Francisco Navarro ◽  
Jürgen Gailer ◽  
José Luiz Gómez-Ariza
Keyword(s):  
Mass Spectrometry ◽  
Molecular Mass ◽  
Mus Musculus ◽  
Inorganic Mercury ◽  
Toxicological Effects ◽  
Molecular Mass Spectrometry

Atomic (HPLC-ICP-MS) and molecular mass spectrometry (ESI-Q-TOF) to study cis-platin interactions with serum proteins

2008 ◽  
Vol 23 (3) ◽  
pp. 378-384 ◽  
Author(s):  
Diego Esteban-Fernández ◽  
M. Montes-Bayón ◽  
E. Blanco González ◽  
M. M. Gómez Gómez ◽  
M. A. Palacios ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Molecular Mass ◽  
Serum Proteins ◽  
Icp Ms ◽  
Molecular Mass Spectrometry

scholarly journals verA Gene is Involved in the Step to Make the Xanthone Structure of Demethylsterigmatocystin in Aflatoxin Biosynthesis

2020 ◽  
Vol 21 (17) ◽  
pp. 6389
Author(s):  
Hongmei Zeng ◽  
Jingjing Cai ◽  
Hidemi Hatabayashi ◽  
Hiroyuki Nakagawa ◽  
Hiromitsu Nakajima ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Liquid Chromatography ◽  
Molecular Mass ◽  
Culture Medium ◽  
The Other ◽  
Aflatoxin Biosynthesis ◽  
Liquid Chromatography Mass Spectrometry ◽  
Fluorescent Substance ◽  
Key Enzyme ◽  
Versicolorin A

In the biosynthesis of aflatoxin, verA, ver-1, ordB, and hypA genes of the aflatoxin gene cluster are involved in the pathway from versicolorin A (VA) to demethylsterigmatocystin (DMST). We herein isolated each disruptant of these four genes to determine their functions in more detail. Disruptants of ver-1, ordB, and hypA genes commonly accumulated VA in their mycelia. In contrast, the verA gene disruptant accumulated a novel yellow fluorescent substance (which we named HAMA) in the mycelia as well as culture medium. Feeding HAMA to the other disruptants commonly caused the production of aflatoxins B1 (AFB1) and G1 (AFG1). These results indicate that HAMA pigment is a novel aflatoxin precursor which is involved at a certain step after those of ver-1, ordB, and hypA genes between VA and DMST. HAMA was found to be an unstable substance to easily convert to DMST and sterigmatin. A liquid chromatography-mass spectrometry (LC-MS) analysis showed that the molecular mass of HAMA was 374, and HAMA gave two close major peaks in the LC chromatogram in some LC conditions. We suggest that these peaks correspond to the two conformers of HAMA; one of them would be selectively bound on the substrate binding site of VerA enzyme and then converted to DMST. VerA enzyme may work as a key enzyme in the creation of the xanthone structure of DMST from HAMA.

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