One‐Pot Tandem Michael Addition/Enantioselective Conia‐Ene Cyclization Mediated by Chiral Iron(III)/Silver(I) Cooperative Catalysis

2020 ◽  
Vol 59 (38) ◽  
pp. 16470-16474 ◽  
Author(s):  
Takahiro Horibe ◽  
Masato Sakakibara ◽  
Rin Hiramatsu ◽  
Kazuki Takeda ◽  
Kazuaki Ishihara
Keyword(s):  
Michael Addition ◽  
One Pot ◽  
Cooperative Catalysis

One‐Pot Tandem Michael Addition/Enantioselective Conia‐Ene Cyclization Mediated by Chiral Iron(III)/Silver(I) Cooperative Catalysis

2020 ◽  
Author(s):  
Takahiro Horibe ◽  
Masato Sakakibara ◽  
Rin Hiramatsu ◽  
Kazuki Takeda ◽  
Kazuaki Ishihara
Keyword(s):  
Michael Addition ◽  
One Pot ◽  
Cooperative Catalysis

The first peripherally masked thiol dendrimers: a facile and highly efficient functionalization strategy of polyester dendrimers via one-pot xanthate deprotection/thiol–acrylate Michael addition reactions

2014 ◽  
Vol 50 (50) ◽  
pp. 6574-6577 ◽  
Author(s):  
Sam E. R. Auty ◽  
Oliver Andrén ◽  
Michael Malkoch ◽  
Steven P. Rannard
Keyword(s):  
Michael Addition ◽  
Addition Reactions ◽  
One Pot ◽  
Highly Efficient

We present the first xanthate surface functional dendrimers which undergo rapid one-pot deprotection to thiols and subsequent acrylate Michael addition .

Catalyst-Free One-Pot Synthesis of Novel Heteroarylamine Substituted Furo[3,2-c]coumarins

Synlett ◽  
2018 ◽  
Vol 29 (12) ◽  
pp. 1589-1592 ◽  
Author(s):  
Abolfazl Olyaei ◽  
Mahnaz Saraei ◽  
Reyhaneh Khoeiniha
Keyword(s):  
Michael Addition ◽  
Aldol Condensation ◽  
Ring Closure ◽  
Dehydration Reaction ◽  
One Pot ◽  
Catalyst Free ◽  
One Pot Synthesis ◽  
Tandem Process ◽  
First Time

A high-yielding cyclocondensation of 4-hydroxycoumarin, phenylglyoxal monohydrate, and heteroarylamines proceeds without catalysis, which gives novel functionalized furo[3,2-c]coumarins and heteroarylamino alkylation of coumarin products in acetonitrile under reflux, is reported for the first time. This tandem process involves sequentially an aldol condensation, Michael addition, a ring closure, and dehydration reaction.

One-Pot Synthesis of Highly Substituted Allenylidene Derivatives via Palladium- or Nickel-Catalyzed Tandem Michael Addition-Cyclization Reaction

2009 ◽  
Vol 351 (1-2) ◽  
pp. 141-146 ◽  
Author(s):  
Yun Shi ◽  
Jing Huang ◽  
Yan-Fang Yang ◽  
Lu-Yong Wu ◽  
Yan-Ning Niu ◽  
...  
Keyword(s):  
Michael Addition ◽  
Cyclization Reaction ◽  
One Pot ◽  
One Pot Synthesis

Uncatalyzed diastereoselective synthesis of alkyliminofurochromone-derived benzylmalononitriles via a three-component cascade reaction: competition between Diels–Alder cycloaddition and Michael addition

2021 ◽  
Author(s):  
Mohammad Bagher Teimouri ◽  
Zahra Mokhtare ◽  
Hamid Reza Khavasi
Keyword(s):  
Michael Addition ◽  
Heterocyclic Ring ◽  
Cascade Reaction ◽  
Diels Alder ◽  
Chemical Bonds ◽  
Diastereoselective Synthesis ◽  
Atom Economy ◽  
One Pot

Three new chemical bonds and three stereogenic centres and one heterocyclic ring were assembled stereoselectively in a convenient high atom-economy one-pot operation.

ChemInform Abstract: One-Pot Three-Component Syntheses of Indoloquinolizidine Derivatives Using an Organocatalytic Michael Addition and Subsequent Pictet-Spengler Cyclization.

ChemInform ◽  
2012 ◽  
Vol 43 (7) ◽  
pp. no-no
Author(s):  
Xiaoyu Wu ◽  
Xiaoyang Dai ◽  
Huihui Fang ◽  
Linlin Nie ◽  
Jie Chen ◽  
...  
Keyword(s):  
Michael Addition ◽  
One Pot

Efficient Synthesis of 3-Amino-1,5-benzodiazepine-2-one Derivatives

Synlett ◽  
2017 ◽  
Vol 28 (10) ◽  
pp. 1183-1186 ◽  
Author(s):  
Nobuhiro Obara ◽  
Takeshi Watanabe ◽  
Tomohiro Asakawa ◽  
Toshiyuki Kan ◽  
Takao Tanaka
Keyword(s):  
Michael Addition ◽  
Convenient Method ◽  
Addition Reaction ◽  
Efficient Synthesis ◽  
Michael Addition Reaction ◽  
One Pot ◽  
Simple Method ◽  
The Michael Addition

A convenient method for synthesizing 3-amino-1,5-benzodiazepine-2-one via the Michael addition reaction of o-phenylenediamine with dehydroalanine ester derivatives, followed by cyclization, was developed. This simple method was used to obtain a variety of N-substituted 3-amino-1,5-benzodiazepine-2-ones in one pot with good yields.

Access to 3-Arylindoles through a Tandem One-Pot Protocol Involving Dearomatization, a Regioselective Michael Addition Reaction, and Rearomatization

2014 ◽  
Vol 2014 (12) ◽  
pp. 2565-2575 ◽  
Author(s):  
Santhosh Kumar Chittimalla ◽  
Chennakesavulu Bandi ◽  
Sireesha Putturu ◽  
Rajesh Kuppusamy ◽  
Kevin Christopher Boellaard ◽  
...  
Keyword(s):  
Michael Addition ◽  
Addition Reaction ◽  
Michael Addition Reaction ◽  
One Pot
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