scholarly journals A Renal‐Clearable Duplex Optical Reporter for Real‐Time Imaging of Contrast‐Induced Acute Kidney Injury

2019 ◽  
Vol 58 (49) ◽  
pp. 17796-17804 ◽  
Author(s):  
Jiaguo Huang ◽  
Yan Lyu ◽  
Jingchao Li ◽  
Penghui Cheng ◽  
Yuyan Jiang ◽  
...  
Keyword(s):  
Acute Kidney Injury ◽  
Real Time ◽  
Kidney Injury ◽  
Real Time Imaging

Ultrasound

2015 ◽  
Author(s):  
Toby Wells ◽  
Simon J. Freeman
Keyword(s):  
Acute Kidney Injury ◽  
Ionizing Radiation ◽  
Renal Biopsy ◽  
Real Time ◽  
Imaging Technique ◽  
Imaging Modality ◽  
Kidney Injury ◽  
Paediatric Radiology ◽  
Renal Transplants ◽  
Real Time Imaging

Ultrasound assists nephrologists in many situations. It is essential in excluding obstruction as the cause of acute kidney injury, but it also helps to reach other diagnoses and guides interventions such as renal biopsy and placement of lines for dialysis and evaluating dialysis fistulae. It is the imaging technique of choice in assessing renal transplants. It has advantages: it does not involve ionizing radiation, allows rapid real-time imaging, is relatively inexpensive, and can be performed at the patient’s bedside. Ultrasound is the primary imaging modality in paediatric radiology for most conditions, largely because it does not involve ionizing radiation. The strengths and limitations of ultrasound need to be understood to ensure that the technique is applied appropriately.

scholarly journals A Renal‐Clearable Duplex Optical Reporter for Real‐Time Imaging of Contrast‐Induced Acute Kidney Injury

2019 ◽  
Vol 131 (49) ◽  
pp. 17960-17968 ◽  
Author(s):  
Jiaguo Huang ◽  
Yan Lyu ◽  
Jingchao Li ◽  
Penghui Cheng ◽  
Yuyan Jiang ◽  
...  
Keyword(s):  
Acute Kidney Injury ◽  
Real Time ◽  
Kidney Injury ◽  
Real Time Imaging

Clearance and beyond: the complementary roles of GFR measurement and injury biomarkers in acute kidney injury (AKI)

2011 ◽  
Vol 301 (4) ◽  
pp. F697-F707 ◽  
Author(s):  
Zoltán H. Endre ◽  
John W. Pickering ◽  
Robert J. Walker
Keyword(s):  
Acute Kidney Injury ◽  
Serum Creatinine ◽  
Real Time ◽  
Renal Injury ◽  
Kidney Injury ◽  
Predictive Performance ◽  
Causal Pathways ◽  
Real Time Measurement ◽  
Diagnostic Potential ◽  
Baseline Information

Acute kidney injury (AKI) is a common and frequently fatal illness in critically ill patients. The reliance on daily measurements of serum creatinine as a surrogate of glomerular filtration rate (GFR) not only delays diagnosis and development of successful therapies but also hinders insight into the pathophysiology of human AKI. Measurement of GFR under non-steady-state conditions remains an elusive gold standard against which biomarkers of renal injury need to be judged. Approaches to the rapid (near real-time) measurement of GFR are explored. Even if real-time GFR was available, absent baseline information will always limit diagnosis of AKI based on GFR or serum creatinine to a detection of change. Biomarkers of renal cellular injury have provided new strategies to facilitate detection and early intervention in AKI. However, the diagnostic and predictive performance of urinary biomarkers of injury vary, depending on both the time after renal injury and on the preinjury GFR. Progress in understanding the role of each novel biomarker in the causal pathways of AKI promises to enhance their diagnostic potential. We predict that combining rapid measures of GFR with biomarkers of renal injury will yield substantive progress in the treatment of AKI.

Impact of real-time electronic alerting of acute kidney injury on therapeutic intervention and progression of RIFLE class*

2012 ◽  
Vol 40 (4) ◽  
pp. 1164-1170 ◽  
Author(s):  
Kirsten Colpaert ◽  
Eric A. Hoste ◽  
Kristof Steurbaut ◽  
Dominique Benoit ◽  
Sofie Van Hoecke ◽  
...  
Keyword(s):  
Acute Kidney Injury ◽  
Real Time ◽  
Therapeutic Intervention ◽  
Kidney Injury

Continuous Real-Time Urine Output Monitoring for Early Detection of Acute Kidney Injury

2011 ◽  
pp. 194-200 ◽  
Author(s):  
Anthi Panagiotou ◽  
Francesco Garzotto ◽  
Silvia Gramaticopolo ◽  
Pasquale Piccinni ◽  
Chiara Trentin ◽  
...  
Keyword(s):  
Acute Kidney Injury ◽  
Early Detection ◽  
Real Time ◽  
Urine Output ◽  
Kidney Injury ◽  
Output Monitoring

scholarly journals Scoping review exploring the impact of digital systems on processes and outcomes in the care management of acute kidney injury and progress towards establishing learning healthcare systems

2021 ◽  
Vol 28 (1) ◽  
pp. e100345
Author(s):  
Clair Ka Tze Chew ◽  
Helen Hogan ◽  
Yogini Jani
Keyword(s):  
Acute Kidney Injury ◽  
Real Time ◽  
Clinical Data ◽  
Early Recognition ◽  
Kidney Injury ◽  
Healthcare Systems ◽  
Digital Systems ◽  
Stakeholder Perspectives ◽  
Micro Level ◽  
The Impact

ObjectivesDigital systems have long been used to improve the quality and safety of care when managing acute kidney injury (AKI). The availability of digitised clinical data can also turn organisations and their networks into learning healthcare systems (LHSs) if used across all levels of health and care. This review explores the impact of digital systems i.e. on patients with AKI care, to gauge progress towards establishing LHSs and to identify existing gaps in the research.MethodsEmbase, PubMed, MEDLINE, Cochrane, Scopus and Web of Science databases were searched. Studies of real-time or near real-time digital AKI management systems which reported process and outcome measures were included.ResultsThematic analysis of 43 studies showed that most interventions used real-time serum creatinine levels to trigger responses to enable risk prediction, early recognition of AKI or harm prevention by individual clinicians (micro level) or specialist teams (meso level). Interventions at system (macro level) were rare. There was limited evidence of change in outcomes.DiscussionWhile the benefits of real-time digital clinical data at micro level for AKI management have been evident for some time, their application at meso and macro levels is emergent therefore limiting progress towards establishing LHSs. Lack of progress is due to digital maturity, system design, human factors and policy levers.ConclusionFuture approaches need to harness the potential of interoperability, data analytical advances and include multiple stakeholder perspectives to develop effective digital LHSs in order to gain benefits across the system.

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