scholarly journals Rapid Aqueous Late‐Stage Radiolabelling of [GaF 3 (BnMe 2 ‐tacn)] by 18 F/ 19 F Isotopic Exchange: Towards New PET Imaging Probes

2018 ◽  
Vol 57 (22) ◽  
pp. 6658-6661 ◽  
Author(s):  
Francesco M. Monzittu ◽  
Imtiaz Khan ◽  
William Levason ◽  
Sajinder K. Luthra ◽  
Graeme McRobbie ◽  
...  
Keyword(s):  
Pet Imaging ◽  
Late Stage ◽  
Isotopic Exchange ◽  
Imaging Probes

scholarly journals Rapid Aqueous Late‐Stage Radiolabelling of [GaF 3 (BnMe 2 ‐tacn)] by 18 F/ 19 F Isotopic Exchange: Towards New PET Imaging Probes

2018 ◽  
Vol 130 (22) ◽  
pp. 6768-6771 ◽  
Author(s):  
Francesco M. Monzittu ◽  
Imtiaz Khan ◽  
William Levason ◽  
Sajinder K. Luthra ◽  
Graeme McRobbie ◽  
...  
Keyword(s):  
Pet Imaging ◽  
Late Stage ◽  
Isotopic Exchange ◽  
Imaging Probes

PET Imaging of Adenosine Receptors in Diseases

2019 ◽  
Vol 19 (16) ◽  
pp. 1445-1463 ◽  
Author(s):  
Jindian Li ◽  
Xingfang Hong ◽  
Guoquan Li ◽  
Peter S. Conti ◽  
Xianzhong Zhang ◽  
...  
Keyword(s):  
Pet Imaging ◽  
Adenosine Receptors ◽  
Neurological Diseases ◽  
G Protein Coupled Receptors ◽  
Extracellular Adenosine ◽  
Positron Emission ◽  
Imaging Probes ◽  
Pet Probes ◽  
Cancer And Inflammation ◽  
G Protein Coupled

Adenosine receptors (ARs) are a class of purinergic G-protein-coupled receptors (GPCRs). Extracellular adenosine is a pivotal regulation molecule that adjusts physiological function through the interaction with four ARs: A1R, A2AR, A2BR, and A3R. Alterations of ARs function and expression have been studied in neurological diseases (epilepsy, Alzheimer’s disease, and Parkinson’s disease), cardiovascular diseases, cancer, and inflammation and autoimmune diseases. A series of Positron Emission Tomography (PET) probes for imaging ARs have been developed. The PET imaging probes have provided valuable information for diagnosis and therapy of diseases related to alterations of ARs expression. This review presents a concise overview of various ARs-targeted radioligands for PET imaging in diseases. The most recent advances in PET imaging studies by using ARs-targeted probes are briefly summarized.

scholarly journals Fluorinated PET imaging probes targeting fibroblast activation protein: radiolabeling and preclinical evaluation

2021 ◽  
Vol 96-97 ◽  
pp. S40-S41
Author(s):  
Filipe Elvas ◽  
Muhammet Tanc ◽  
Yentl Van Rymenant ◽  
Lucas Beroske ◽  
Stef De Lombaerde ◽  
...  
Keyword(s):  
Pet Imaging ◽  
Fibroblast Activation Protein ◽  
Preclinical Evaluation ◽  
Fibroblast Activation ◽  
Imaging Probes

Late-Stage 18F/19F Isotopic Exchange for the Synthesis of 18F-Labeled Sulfamoyl Fluorides

2021 ◽  
Author(s):  
Min Ho Jeon ◽  
Young-Do Kwon ◽  
Min Pyeong Kim ◽  
Gianluca Bartolini Torres ◽  
Jeong Kon Seo ◽  
...  
Keyword(s):  
Late Stage ◽  
Isotopic Exchange

Synthesis and biological evaluation of 18F-labled 2-phenylindole derivatives as PET imaging probes for β-amyloid plaques

2013 ◽  
Vol 21 (13) ◽  
pp. 3708-3714 ◽  
Author(s):  
Hualong Fu ◽  
Lihai Yu ◽  
Mengchao Cui ◽  
Jinming Zhang ◽  
Xiaojun Zhang ◽  
...  
Keyword(s):  
Pet Imaging ◽  
Amyloid Plaques ◽  
Biological Evaluation ◽  
Imaging Probes ◽  
Β Amyloid ◽  
Synthesis And Biological Evaluation

Preparation and evaluation of L- and D-5-[ 18 F]fluorotryptophan as PET imaging probes for indoleamine and tryptophan 2,3-dioxygenases

2017 ◽  
Vol 51 ◽  
pp. 10-17 ◽  
Author(s):  
Tang Tang ◽  
Herman S. Gill ◽  
Annie Ogasawara ◽  
Jeff N. Tinianow ◽  
Alexander N. Vanderbilt ◽  
...  
Keyword(s):  
Pet Imaging ◽  
Imaging Probes ◽  
Preparation And Evaluation

scholarly journals Evaluation of potential PET imaging probes for the orexin 2 receptors

2013 ◽  
Vol 40 (8) ◽  
pp. 1000-1005 ◽  
Author(s):  
Changning Wang ◽  
Colin M. Wilson ◽  
Christian K. Moseley ◽  
Stephen M. Carlin ◽  
Shirley Hsu ◽  
...  
Keyword(s):  
Pet Imaging ◽  
Imaging Probes

scholarly journals A Fluoride-Derived Electrophilic Late-Stage Fluorination Reagent for PET Imaging

Science ◽  
2011 ◽  
Vol 334 (6056) ◽  
pp. 639-642 ◽  
Author(s):  
E. Lee ◽  
A. S. Kamlet ◽  
D. C. Powers ◽  
C. N. Neumann ◽  
G. B. Boursalian ◽  
...  
Keyword(s):  
Pet Imaging ◽  
Late Stage
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