High‐Resolution Crystal Structure of a Silver(I)–RNA Hybrid Duplex Containing Watson–Crick‐like CSilver(I)C Metallo‐Base Pairs

2015 ◽  
Vol 54 (45) ◽  
pp. 13323-13326 ◽  
Author(s):  
Jiro Kondo ◽  
Yoshinari Tada ◽  
Takenori Dairaku ◽  
Hisao Saneyoshi ◽  
Itaru Okamoto ◽  
...  
Keyword(s):  
Crystal Structure ◽  
High Resolution ◽  
Base Pairs ◽  
Hybrid Duplex

High‐Resolution Crystal Structure of a Silver(I)–RNA Hybrid Duplex Containing Watson–Crick‐like CSilver(I)C Metallo‐Base Pairs

2015 ◽  
Vol 127 (45) ◽  
pp. 13521-13524 ◽  
Author(s):  
Jiro Kondo ◽  
Yoshinari Tada ◽  
Takenori Dairaku ◽  
Hisao Saneyoshi ◽  
Itaru Okamoto ◽  
...  
Keyword(s):  
Crystal Structure ◽  
High Resolution ◽  
Base Pairs ◽  
Hybrid Duplex

scholarly journals Crystal structure of metallo-DNA duplex containing T-Hg(II)-T base pairs

2014 ◽  
Vol 70 (a1) ◽  
pp. C1375-C1375
Author(s):  
Jiro Kondo ◽  
Tom Yamada ◽  
Chika Hirose ◽  
Itaru Okamoto ◽  
Yoshiyuki Tanaka ◽  
...  
Keyword(s):  
Crystal Structure ◽  
Aqueous Solution ◽  
Nucleic Acid ◽  
Helical Conformation ◽  
Helical Axis ◽  
Dna Duplex ◽  
Base Pairs ◽  
Imino Proton ◽  
Sensing System ◽  
Hybrid Duplex

The DNA duplex containing mercury-mediated base pairs (T-Hg(II)-T) is an attractive biomacromolecular nanomaterials. In a recent study, it was confirmed that the Hg(II) ion significantly stabilizes a DNA duplex by binding selectively to a T-T mispair [1]. Based on the phenomenon observed, a DNA-based sensing system that selectively and sensitively detects Hg(II) ions in aqueous solution was developed [2]. In the present study, we have solved the first crystal structure of a B-form DNA duplex containing two consecutive T-Hg(II)-T base pairs [3]. The Hg(II) ion occupies the center between two T residues. The geometry of the T-Hg(II)-T base pair is very similar to that of the canonical Watson-Crick base pairs. The distance of N3-Hg(II) bond is 2.0 Å, suggesting that the N3 nitrogen releases an imino-proton even at neutral pH (pKa of N3 position of T is 9.8) and directly bonds to Hg(II). In the B-form DNA, the helical axis runs through the center of base pairs, and the Hg(II) ions are therefore aligned along the helical axis. The distance between the two neighboring Hg(II) ions is 3.3 Å. The relatively short Hg(II)-Hg(II) distance indicates that the metallophilic attraction could exit between them and may stabilize the B-form duplex. To support this, the DNA duplex is largely distorted and adopts an unusual non-helical conformation in the absence of Hg(II). In conclusion, the Hg(II) ion is essential for maintaining the B-form conformation of the DNA duplex containing T-T mispairs. The structure of the Hg(II)-DNA hybrid duplex itself and the Hg(II)-induced structural switching from the non-helical form to the B-form provide the basis for the structure-based design of metal-conjugated nucleic acid nanomaterials.

2‘-Deoxyisoguanosine Adopts More than One Tautomer To Form Base Pairs with Thymidine Observed by High-Resolution Crystal Structure Analysis†

Biochemistry ◽  
1998 ◽  
Vol 37 (31) ◽  
pp. 10897-10905 ◽  
Author(s):  
Howard Robinson ◽  
Yi-Gui Gao ◽  
Cornelia Bauer ◽  
Christopher Roberts ◽  
Christopher Switzer ◽  
...  
Keyword(s):  
Crystal Structure ◽  
High Resolution ◽  
Structure Analysis ◽  
Crystal Structure Analysis ◽  
Base Pairs

High resolution STEM imaging study on high Tc superconductor YBa2CuaO7-x

1988 ◽  
Vol 46 ◽  
pp. 882-883
Author(s):  
H.-J. Ou ◽  
J. M. Cowley
Keyword(s):  
Crystal Structure ◽  
High Resolution ◽  
Grain Boundary ◽  
Strong Field ◽  
Imaging Study ◽  
Structure Defects ◽  
High Tc ◽  
High Tc Superconductor ◽  
Diffraction Patterns ◽  
Lattice Planes

Using the dedicate VG-HB5 STEM microscope, the crystal structure of high Tc superconductor of YBa2Cu3O7-x has been studied via high resolution STEM (HRSTEM) imaging and nanobeam (∽3A) diffraction patterns. Figure 1(a) and 2(a) illustrate the HRSTEM image taken at 10' times magnification along [001] direction and [100] direction, respectively. In figure 1(a), a grain boundary with strong field contrast is seen between two crystal regions A and B. The grain boundary appears to be parallel to a (110) plane, although it is not possible to determine [100] and [001] axes as it is in other regions which contain twin planes [3]. Following the horizontal lattice lines, from left to right across the grain boundary, a lattice bending of ∽4° is noticed. Three extra lattice planes, indicated by arrows, were found to terminate at the grain boundary and form dislocations. It is believed that due to different chemical composition, such structure defects occur during crystal growth. No bending is observed along the vertical lattice lines.

Perovskite Solar Cells: Crystal Structure and Interface Architecture with High Resolution TEM Observations

2017 ◽  
Author(s):  
Satoshi Uchida ◽  
Tae Woong Kim ◽  
Ludmila Cojocaru ◽  
Takashi Kondo ◽  
Hiroshi Segawa
Keyword(s):  
Crystal Structure ◽  
Solar Cells ◽  
High Resolution ◽  
Perovskite Solar Cells ◽  
High Resolution Tem

scholarly journals Refined crystal structure of an octanucleotide duplex with I.T. mismatched base pairs

1989 ◽  
Vol 17 (1) ◽  
pp. 55-72 ◽  
Author(s):  
W.B.T. Cruse ◽  
J. Aymani ◽  
Olga Kennard ◽  
Tom Brown ◽  
Audrey G.C. Jack ◽  
...  
Keyword(s):  
Crystal Structure ◽  
Base Pairs

Molecular and Crystal Structure of d(CGCGmo4CG): N4−Methoxy-cytosineguanine Base Pairs in Z-DNA

1990 ◽  
Vol 9 (3) ◽  
pp. 467-469 ◽  
Author(s):  
L. Van Meervelt ◽  
M. H. Moore ◽  
P. Kong Thoo Lin ◽  
D. M. Brown ◽  
O. Kennard
Keyword(s):  
Crystal Structure ◽  
Molecular And Crystal Structure ◽  
Base Pairs ◽  
Z Dna
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