Scalable Synthesis of the Potent HIV Inhibitor BMS-986001 by Non-Enzymatic Dynamic Kinetic Asymmetric Transformation (DYKAT)

2015 ◽  
Vol 54 (24) ◽  
pp. 7185-7188 ◽  
Author(s):  
Adrian Ortiz ◽  
Tamas Benkovics ◽  
Gregory L. Beutner ◽  
Zhongping Shi ◽  
Michael Bultman ◽  
...  
Keyword(s):  
Scalable Synthesis ◽  
Asymmetric Transformation ◽  
Hiv Inhibitor

ChemInform Abstract: Scalable Synthesis of the Potent HIV Inhibitor BMS-986001 by Non-enzymatic Dynamic Kinetic Asymmetric Transformation (DYKAT).

ChemInform ◽  
2015 ◽  
Vol 46 (42) ◽  
pp. no-no
Author(s):  
Adrian Ortiz ◽  
Tamas Benkovics ◽  
Gregory L. Beutner ◽  
Zhongping Shi ◽  
Michael Bultman ◽  
...  
Keyword(s):  
Scalable Synthesis ◽  
Asymmetric Transformation ◽  
Hiv Inhibitor

Scalable Synthesis of the Potent HIV Inhibitor BMS-986001 by Non-Enzymatic Dynamic Kinetic Asymmetric Transformation (DYKAT)

2015 ◽  
Vol 127 (24) ◽  
pp. 7291-7294 ◽  
Author(s):  
Adrian Ortiz ◽  
Tamas Benkovics ◽  
Gregory L. Beutner ◽  
Zhongping Shi ◽  
Michael Bultman ◽  
...  
Keyword(s):  
Scalable Synthesis ◽  
Asymmetric Transformation ◽  
Hiv Inhibitor

Scalable Synthesis of Functionalized Ferrocenyl Azides and Amines Enabled by Flow Chemistry

2019 ◽  
Author(s):  
Merlin Kleoff ◽  
Johannes Schwan ◽  
Lisa Boeser ◽  
Bence Hartmayer ◽  
Mathias Christmann ◽  
...  
Keyword(s):  
Reaction Time ◽  
Heterogeneous Reaction ◽  
Reduction Process ◽  
Flow Chemistry ◽  
Subsequent Reaction ◽  
Scalable Synthesis ◽  
High Yields ◽  
Reactor Section

A scalable access to functionalized 1,1’- and 1,2-ferrocenyl azides has been realized in flow. By halogen‒lithium exchange of ferrocenyl halides and subsequent reaction with tosyl azide, a variety of functionalized ferrocenyl azides was obtained in high yields. To allow a scalable preparation of these potentially explosive compounds, an efficient flow protocol was developed accelerating the reaction time to minutes and circumventing accumulation of potentially hazardous intermediates. Switching from homogeneous to triphasic flow amidst process was key for handling a heterogeneous reaction mixture formed after a heated reactor section. The corresponding and synthetically versatile ferrocenyl amines were then prepared by a reliable reduction process.

Simple and scalable synthesis of urchin-like ZnO nanoparticles via a microwave-assisted drying process

2021 ◽  
Author(s):  
Myung Sik Choi ◽  
Han Gil Na ◽  
Gyu Sam Shim ◽  
Jae Hee Cho ◽  
Min Young Kim ◽  
...  
Keyword(s):  
Zno Nanoparticles ◽  
Drying Process ◽  
Microwave Assisted ◽  
Scalable Synthesis

scholarly journals Towards a Greener and Scalable Synthesis of Na 2 Ti 6 O 13 Nanorods and Their Application as Anodes in Batteries for Grid‐Level Energy Storage

2021 ◽  
Vol 9 (1) ◽  
pp. 2170011
Author(s):  
Dario M. De Carolis ◽  
Dragoljub Vrankovic ◽  
Samira A. Kiefer ◽  
Enrico Bruder ◽  
Michael Thomas Dürrschnabel ◽  
...  
Keyword(s):  
Energy Storage ◽  
Level Energy ◽  
Scalable Synthesis ◽  
Grid Level

Scalable Synthesis of Graphene on Patterned Ni and Transfer

2010 ◽  
Vol 57 (12) ◽  
pp. 3472-3476 ◽  
Author(s):  
Yanjie Wang ◽  
Congqin Miao ◽  
Bo-chao Huang ◽  
Jing Zhu ◽  
Wei Liu ◽  
...  
Keyword(s):  
Scalable Synthesis

Scalable synthesis of selective hydrodeoxygenation inverted Pd@TiO2 nanocatalysts

2021 ◽  
Author(s):  
Pinaki Ranadive ◽  
Zachary Blanchette ◽  
Alexander Spanos ◽  
J. Will Medlin ◽  
Nicholas Brunelli
Keyword(s):  
Scalable Synthesis

scholarly journals Scalable Synthesis of 17S-FD-895 Expands the Structural Understanding of Splice Modulatory Activity

2020 ◽  
Vol 1 (12) ◽  
pp. 100277
Author(s):  
Warren C. Chan ◽  
James J. La Clair ◽  
Brian León ◽  
Kelsey A. Trieger ◽  
Martijn Q. Slagt ◽  
...  
Keyword(s):  
Scalable Synthesis
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