scholarly journals Self-Assembly of Thermally Responsive Nanoparticles of a Genetically Encoded Peptide Polymer by Drug Conjugation

2012 ◽  
Vol 52 (6) ◽  
pp. 1683-1687 ◽  
Author(s):  
Jonathan R. McDaniel ◽  
Jayanta Bhattacharyya ◽  
Kevin B. Vargo ◽  
Wafa Hassouneh ◽  
Daniel A. Hammer ◽  
...  
2012 ◽  
Vol 125 (6) ◽  
pp. 1727-1731 ◽  
Author(s):  
Jonathan R. McDaniel ◽  
Jayanta Bhattacharyya ◽  
Kevin B. Vargo ◽  
Wafa Hassouneh ◽  
Daniel A. Hammer ◽  
...  

2007 ◽  
Vol 45 (20) ◽  
pp. 4720-4732 ◽  
Author(s):  
Iliyana V. Berlinova ◽  
Plamen V. Iliev ◽  
Nikolay G. Vladimirov ◽  
Christo P. Novakov

Polymer ◽  
2005 ◽  
Vol 46 (7) ◽  
pp. 2059-2067 ◽  
Author(s):  
Ana N. Nedelcheva ◽  
Christo P. Novakov ◽  
Stojan M. Miloshev ◽  
Iliyana V. Berlinova

2010 ◽  
Vol 49 (25) ◽  
pp. 4257-4260 ◽  
Author(s):  
Wookhyun Kim ◽  
Julie Thévenot ◽  
Emmanuel Ibarboure ◽  
Sébastien Lecommandoux ◽  
Elliot L. Chaikof

2010 ◽  
Vol 122 (25) ◽  
pp. 4353-4356 ◽  
Author(s):  
Wookhyun Kim ◽  
Julie Thévenot ◽  
Emmanuel Ibarboure ◽  
Sébastien Lecommandoux ◽  
Elliot L. Chaikof

2018 ◽  
Vol 122 (22) ◽  
pp. 6072-6078 ◽  
Author(s):  
Victoria I. Michailova ◽  
Denitsa B. Momekova ◽  
Hristiana A. Velichkova ◽  
Evgeni H. Ivanov ◽  
Rumiana K. Kotsilkova ◽  
...  

2017 ◽  
Vol 8 (18) ◽  
pp. 2815-2823 ◽  
Author(s):  
Xiaotian Ji ◽  
Li Liu ◽  
Hanying Zhao

Thermal-responsive polymer chains with pendant lysozyme molecules were prepared via a “grafting to” approach. The bioconjugates were able to self-assemble into mesoglobules at a temperature above their cloud point.


2006 ◽  
Vol 6 (9) ◽  
pp. 2896-2901 ◽  
Author(s):  
Yan Zhang ◽  
Wuli Yang ◽  
Changchun Wang ◽  
Wei Wu ◽  
Shoukuan Fu

Thermally-responsive graft copolymer of poly(N-isopropylacrylamide-co-N-(hydroxylmethyl)acrylamide)-g-poly(lactide) was synthesized by ring-opening polymerization of D,L-lactide (LA). The polymerization was initiated by the hydroxy group of poly(N-isopropyl acrylamide-co-N-(hydroxylmethyl)acrylamide), using stannous octoate as catalyst. The resulting polymer was temperature-sensitive and the lower critical solution temperature (LCST) was affected by their composition. The chemical structure and physical properties of the grafted copolymers were investigated by various methods. Nanocontainers formed from the self-assembly of poly(N-isopropylacrylamide-co-N-(hydroxylmethyl) acrylamide)-g-poly(lactide) were characterized by transmission electron microscopy (TEM), and a spherical structure was observed. Dynamic light scattering (DLS) results indicate that the particle size increased with the increase of polylactide content in the copolymer. The properties of this polymer are interesting for both industrial application and fundamental research. In particular it will combine a spatial specificity in a passive manner and a temperature-responsive active targeting mechanism for drug delivery system.


2016 ◽  
Vol 2016 ◽  
pp. 1-9 ◽  
Author(s):  
Yibo Feng ◽  
Qingquan Zhang ◽  
Hui Li ◽  
Yongjin Chen ◽  
Cong Wang

A novel thermally responsive hydrogel (TRH) has been demonstrated by confining poly(ethylene oxide), poly(propylene oxide), and poly(ethylene oxide) triblock-copolymer (EPE) molecules into the pores of polymer framework. Aqueous EPE copolymer molecule had a tendency to aggregate to form clusters gradually and precipitated from water when the temperature is above a cloudy point. By adding EPE molecules into the acrylamide (AM) monomer solution, the mixture can be fabricated as uniform and transparent hydrogel via controlled radical polymerization. The polyacrylamide hydrogel is produced with a switchable optical property when subjecting to temperature variation. Such reversible thermally responsive material can be utilized as a functional material for smart window application. Additionally, the thermal responsive hydrogel is an inexpensive material, which is readily applicable as smart windows with significant reduction in material cost.


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