Catalytic Asymmetric Activation of a C sp 3H Bond Adjacent to a Nitrogen Atom: A Versatile Approach to Optically Active α-Alkyl α-Amino Acids and C1-Alkylated Tetrahydroisoquinoline Derivatives

Gen Zhang; Yaohu Zhang; Rui Wang

doi:10.1002/anie.201105123

Catalytic Asymmetric Activation of a C sp 3H Bond Adjacent to a Nitrogen Atom: A Versatile Approach to Optically Active α-Alkyl α-Amino Acids and C1-Alkylated Tetrahydroisoquinoline Derivatives

Angewandte Chemie International Edition ◽

10.1002/anie.201105123 ◽

2011 ◽

Vol 50 (44) ◽

pp. 10429-10432 ◽

Cited By ~ 218

Author(s):

Gen Zhang ◽

Yaohu Zhang ◽

Rui Wang

Keyword(s):

Amino Acids ◽

Nitrogen Atom ◽

Optically Active ◽

Catalytic Asymmetric ◽

Asymmetric Activation

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Catalytic Asymmetric Activation of a C sp 3H Bond Adjacent to a Nitrogen Atom: A Versatile Approach to Optically Active α-Alkyl α-Amino Acids and C1-Alkylated Tetrahydroisoquinoline Derivatives

Angewandte Chemie ◽

10.1002/ange.201105123 ◽

2011 ◽

Vol 123 (44) ◽

pp. 10613-10616 ◽

Cited By ~ 69

Author(s):

Gen Zhang ◽

Yaohu Zhang ◽

Rui Wang

Keyword(s):

Amino Acids ◽

Nitrogen Atom ◽

Optically Active ◽

Catalytic Asymmetric ◽

Asymmetric Activation

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ChemInform Abstract: Catalytic Asymmetric Activation of a C(sp3)-H Bond Adjacent to a Nitrogen Atom: A Versatile Approach to Optically Active α-Alkyl α-Amino Acids and C1-Alkylated Tetrahydroisoquinoline Derivatives.

ChemInform ◽

10.1002/chin.201211023 ◽

2012 ◽

Vol 43 (11) ◽

pp. no-no

Author(s):

Gen Zhang ◽

Yaohu Zhang ◽

Rui Wang

Keyword(s):

Amino Acids ◽

Nitrogen Atom ◽

Optically Active ◽

Catalytic Asymmetric ◽

Asymmetric Activation

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Catalytic asymmetric synthesis of optically active β-amino acids

Tetrahedron Letters ◽

10.1016/s0040-4039(01)94476-4 ◽

1978 ◽

Vol 19 (13) ◽

pp. 1119-1120 ◽

Cited By ~ 38

Author(s):

Kazuo Achiwa ◽

Tsunehiko Soga

Keyword(s):

Amino Acids ◽

Asymmetric Synthesis ◽

Optically Active ◽

Catalytic Asymmetric Synthesis ◽

Catalytic Asymmetric

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ChemInform Abstract: Direct Organo-Catalytic Asymmetric α-Amination of Aldehydes - A Simple Approach to Optically Active α-Amino Aldehydes, α-Amino Alcohols, and α-Amino Acids.

ChemInform ◽

10.1002/chin.200239186 ◽

2010 ◽

Vol 33 (39) ◽

pp. no-no

Author(s):

Anders Boegevig ◽

Karsten Juhl ◽

Nagaswamy Kumaragurubaran ◽

Wei Zhuang ◽

Karl Anker Joergensen

Keyword(s):

Amino Acids ◽

Amino Alcohols ◽

Simple Approach ◽

Optically Active ◽

Amino Aldehydes ◽

Catalytic Asymmetric

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ChemInform Abstract: Catalytic Asymmetric Synthesis of Î±-Amino Acid Derivatives: Approaches Toward Green Sustainable Methodology for the Preparation of Optically Active Amino Acids

ChemInform ◽

10.1002/chin.201001240 ◽

2010 ◽

Vol 41 (1) ◽

pp. no-no

Author(s):

Yasuhiro Yamashita ◽

Shu Kobayashi

Keyword(s):

Amino Acids ◽

Amino Acid ◽

Asymmetric Synthesis ◽

Optically Active ◽

Amino Acid Derivatives ◽

Catalytic Asymmetric Synthesis ◽

Catalytic Asymmetric

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ChemInform Abstract: ASYMMETRIC REACTIONS CATALYZED BY CHIRAL METAL COMPLEXES. VII. CATALYTIC ASYMMETRIC SYNTHESIS OF OPTICALLY ACTIVE β-AMINO ACIDS

Chemischer Informationsdienst ◽

10.1002/chin.197828305 ◽

1978 ◽

Vol 9 (28) ◽

Author(s):

K. ACHIWA ◽

T. SOGA

Keyword(s):

Amino Acids ◽

Metal Complexes ◽

Asymmetric Synthesis ◽

Optically Active ◽

Asymmetric Reactions ◽

Catalytic Asymmetric Synthesis ◽

Catalytic Asymmetric

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ChemInform Abstract: TRANSITION METAL CATALYZED ASYMMETRIC ORGANIC SYNTHESES VIA POLYMER-ATTACHED OPTICALLY ACTIVE PHOSPHINE LIGANDS. SYNTHESIS OF R AMINO ACIDS AND HYDRATROPIC ACID BY HYDROGENATION

Chemischer Informationsdienst ◽

10.1002/chin.197818313 ◽

1978 ◽

Vol 9 (18) ◽

Author(s):

N. TAKAISHI ◽

H. IMAI ◽

C. A. BERTELO ◽

J. K. STILLE

Keyword(s):

Amino Acids ◽

Transition Metal ◽

Optically Active ◽

Phosphine Ligands ◽

Organic Syntheses ◽

Transition Metal Catalyzed ◽

Metal Catalyzed

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Development of a Recyclable Fluorous Chiral Phase-Transfer Catalyst: Application to the Catalytic Asymmetric Synthesis of α-Amino Acids.

ChemInform ◽

10.1002/chin.200435186 ◽

2004 ◽

Vol 35 (35) ◽

Author(s):

Seiji Shirakawa ◽

Youhei Tanaka ◽

Keiji Maruoka

Keyword(s):

Amino Acids ◽

Asymmetric Synthesis ◽

Phase Transfer ◽

Phase Transfer Catalyst ◽

Chiral Phase ◽

Catalytic Asymmetric Synthesis ◽

Catalytic Asymmetric

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ChemInform Abstract: Synthesis of Optically Active 2-Alkyl-3,4-iminobutanoic Acids. β-Amino Acids Containing an Aziridine Heterocycle.

ChemInform ◽

10.1002/chin.200142133 ◽

2010 ◽

Vol 32 (42) ◽

pp. no-no

Author(s):

Jeong-il Park ◽

Guan Rong Tian ◽

Dong H. Kim

Keyword(s):

Amino Acids ◽

Optically Active

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CLXXXIII.—Studies in substituted quaternary azonium compounds containing an asymmetric nitrogen atom. Part II. Resolution of phenylbenzylmethylazonium iodide into optically active components

Journal of the Chemical Society Transactions ◽

10.1039/ct9140501972 ◽

1914 ◽

Vol 105 (0) ◽

pp. 1972-1987

Author(s):

Bawa Kartar Singh

Keyword(s):

Nitrogen Atom ◽

Optically Active ◽

Active Components ◽

Asymmetric Nitrogen

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