Highly Regioselective Synthesis of Spirocyclic Compounds by a Palladium-Catalyzed Intermolecular Tandem Reaction

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Li-Na Guo ◽  
Xin-Hua Duan ◽  
...  
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Li-Na Guo ◽  
Xin-Hua Duan ◽  
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Robert Franke ◽  
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Matthias Beller

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A palladium-catalyzed enantioselective tandem reaction of 2,5-cyclohexadienyl-substituted aryl iodides and carbon or heteroatom nucleophiles has been successfully established by using a chiral H8-BINOL-based phosphoramidite ligand.


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