Organocatalytic One-Pot Asymmetric Synthesis of Functionalized Tricyclic Carbon Frameworks from a Triple-Cascade/Diels–Alder Sequence

2007 ◽  
Vol 46 (3) ◽  
pp. 467-469 ◽  
Author(s):  
Dieter Enders ◽  
Matthias R. M. Hüttl ◽  
Jan Runsink ◽  
Gerhard Raabe ◽  
Bianca Wendt
2007 ◽  
Vol 9 (5) ◽  
pp. 805-808 ◽  
Author(s):  
Yongxiang Liu ◽  
Kui Lu ◽  
Mingji Dai ◽  
Kai Wang ◽  
Wanqing Wu ◽  
...  

ChemInform ◽  
2007 ◽  
Vol 38 (29) ◽  
Author(s):  
Yongxiang Liu ◽  
Kui Li ◽  
Mingji Dai ◽  
Kai Wang ◽  
Wanqing Wu ◽  
...  

1996 ◽  
Vol 74 (1) ◽  
pp. 88-94 ◽  
Author(s):  
Don M. Coltart ◽  
James L. Charlton

The total asymmetric syntheses of (−)-isolariciresinol dimethyl ether (6) and (−)-deoxysikkimotoxin (7) have been carried out, in an attempt to exploit a synthetic strategy recently developed for the synthesis of (−)-deoxypodophyllotoxin (1, R1 = -CH2−, Ar = 3,4,5-trimethoxyphenyl). In so doing, a generalized method for the synthesis of aryltetralin lignans has been developed that should be applicable to a variety of substitution patterns and stereochemistries. A one-pot, 100% regio-selective reduction–lactonization procedure has been developed for the conversion of the ester 18b to (−)-deoxysikkimotoxin, which gave 93% isolated yield in that step. Key words: ortho-quinodimethanes, lignans, Diels–Alder, asymmetric, mandelate.


2016 ◽  
Vol 14 (8) ◽  
pp. 2444-2453 ◽  
Author(s):  
Ji-Yao Li ◽  
Zhi-Long Li ◽  
Wei-Wei Zhao ◽  
Yan-Kai Liu ◽  
Zhi-Ping Tong ◽  
...  

Lactols or cyclic hemiaminals are directly used as nucleophiles in the asymmetric aza-Diels–Alder reaction to synthesize ring-fused piperidine derivatives.


ChemInform ◽  
2007 ◽  
Vol 38 (16) ◽  
Author(s):  
Dieter Enders ◽  
Matthias R. M. Huettl ◽  
Jan Runsink ◽  
Gerhard Raabe ◽  
Bianca Wendt

2016 ◽  
Vol 128 (52) ◽  
pp. 16387-16389 ◽  
Author(s):  
Simon Dochain ◽  
Fabrizio Vetica ◽  
Rakesh Puttreddy ◽  
Kari Rissanen ◽  
Dieter Enders

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