Metal-Mediated DNA Base Pairing and Metal Arrays in Artificial DNA: Towards New Nanodevices

2003 ◽  
Vol 42 (28) ◽  
pp. 3204-3206 ◽  
Author(s):  
Hans-Achim Wagenknecht
Keyword(s):  
Dna Base ◽  
2017 ◽  
Vol 46 (5) ◽  
pp. 622-633 ◽  
Author(s):  
Yusuke Takezawa ◽  
Jens Müller ◽  
Mitsuhiko Shionoya

2007 ◽  
Vol 111 (19) ◽  
pp. 5357-5361 ◽  
Author(s):  
Radi A. Jishi ◽  
Joseph Bragin

2021 ◽  
Vol 12 (1) ◽  
Author(s):  
Jonathan M. Fogg ◽  
Allison K. Judge ◽  
Erik Stricker ◽  
Hilda L. Chan ◽  
Lynn Zechiedrich

AbstractDNA in cells is supercoiled and constrained into loops and this supercoiling and looping influence every aspect of DNA activity. We show here that negative supercoiling transmits mechanical stress along the DNA backbone to disrupt base pairing at specific distant sites. Cooperativity among distant sites localizes certain sequences to superhelical apices. Base pair disruption allows sharp bending at superhelical apices, which facilitates DNA writhing to relieve torsional strain. The coupling of these processes may help prevent extensive denaturation associated with genomic instability. Our results provide a model for how DNA can form short loops, which are required for many essential processes, and how cells may use DNA loops to position nicks to facilitate repair. Furthermore, our results reveal a complex interplay between site-specific disruptions to base pairing and the 3-D conformation of DNA, which influences how genomes are stored, replicated, transcribed, repaired, and many other aspects of DNA activity.


2020 ◽  
Vol 124 (27) ◽  
pp. 5559-5570
Author(s):  
Rongpeng Li ◽  
Chi H. Mak

Science ◽  
2019 ◽  
Vol 366 (6468) ◽  
pp. 965.3-965
Author(s):  
Zibo Chen
Keyword(s):  

2002 ◽  
Vol 106 (40) ◽  
pp. 9319-9324 ◽  
Author(s):  
Eugene S. Kryachko ◽  
Minh Tho Nguyen

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