scholarly journals Synthesis and processing of nanomaterials mediated by living beings

2021 ◽  
Author(s):  
Victor Calvo ◽  
Jose Miguel Gonzalez-Dominguez ◽  
Ana M. Benito ◽  
Wolfgang K. Maser
Keyword(s):  
Synthesis And Processing

scholarly journals Harnessing the Nucleolar DNA Damage Response in Cancer Therapy

Genes ◽  
2021 ◽  
Vol 12 (8) ◽  
pp. 1156
Author(s):  
Jiachen Xuan ◽  
Kezia Gitareja ◽  
Natalie Brajanovski ◽  
Elaine Sanij
Keyword(s):  
Dna Damage ◽  
Dna Repair ◽  
Cancer Therapy ◽  
Dna Damage Response ◽  
Rrna Genes ◽  
Rrna Synthesis ◽  
Pol I ◽  
Clinical Investigations ◽  
Damage Response ◽  
Synthesis And Processing

The nucleoli are subdomains of the nucleus that form around actively transcribed ribosomal RNA (rRNA) genes. They serve as the site of rRNA synthesis and processing, and ribosome assembly. There are 400–600 copies of rRNA genes (rDNA) in human cells and their highly repetitive and transcribed nature poses a challenge for DNA repair and replication machineries. It is only in the last 7 years that the DNA damage response and processes of DNA repair at the rDNA repeats have been recognized to be unique and distinct from the classic response to DNA damage in the nucleoplasm. In the last decade, the nucleolus has also emerged as a central hub for coordinating responses to stress via sequestering tumor suppressors, DNA repair and cell cycle factors until they are required for their functional role in the nucleoplasm. In this review, we focus on features of the rDNA repeats that make them highly vulnerable to DNA damage and the mechanisms by which rDNA damage is repaired. We highlight the molecular consequences of rDNA damage including activation of the nucleolar DNA damage response, which is emerging as a unique response that can be exploited in anti-cancer therapy. In this review, we focus on CX-5461, a novel inhibitor of Pol I transcription that induces the nucleolar DNA damage response and is showing increasing promise in clinical investigations.

scholarly journals Intracellular sites of synthesis and processing of lectin in developing pea cotyledons.

1983 ◽  
Vol 258 (15) ◽  
pp. 9550-9552 ◽  
Author(s):  
T J Higgins ◽  
M J Chrispeels ◽  
P M Chandler ◽  
D Spencer
Keyword(s):  
Synthesis And Processing

scholarly journals Synthesis and processing of alpha-galactosidase A in human fibroblasts. Evidence for different mutations in Fabry disease.

1987 ◽  
Vol 262 (5) ◽  
pp. 2062-2065
Author(s):  
P. Lemansky ◽  
D.F. Bishop ◽  
R.J. Desnick ◽  
A. Hasilik ◽  
K. von Figura
Keyword(s):  
Fabry Disease ◽  
Human Fibroblasts ◽  
Synthesis And Processing ◽  
Alpha Galactosidase

Polymer Synthesis and Processing

2014 ◽  
pp. 1-31 ◽  
Author(s):  
Mahadevappa Y. Kariduraganavar ◽  
Arjumand A. Kittur ◽  
Ravindra R. Kamble
Keyword(s):  
Polymer Synthesis ◽  
Synthesis And Processing

Synthesis and processing of glycoproteins of Varicella-Zoster virus (VZV) as studied with monoclonal antibodies to VZV antigens

Virology ◽  
1983 ◽  
Vol 129 (2) ◽  
pp. 357-368 ◽  
Author(s):  
Toshiomi Okuno ◽  
Koichi Yamanishi ◽  
Kimiyasu Shiraki ◽  
Michiaki Takahashi
Keyword(s):  
Monoclonal Antibodies ◽  
Varicella Zoster Virus ◽  
Varicella Zoster ◽  
Synthesis And Processing

Zirconium Titanate: Synthesis and Processing of Fine Powders Prepared by Chemical Route

2006 ◽  
Vol 530-531 ◽  
pp. 683-688 ◽  
Author(s):  
Valter Ussui ◽  
Dolores Ribeiro Ricci Lazar ◽  
Nelson Batista de Lima ◽  
Ana Helena A. Bressiani ◽  
José Octavio A. Pascoal
Keyword(s):  
Metal Salt ◽  
Ceramic Powder ◽  
Ammonium Hydroxide ◽  
Molar Ratio ◽  
Precipitation Process ◽  
Zirconium Titanate ◽  
X Ray Diffraction ◽  
Chemical Route ◽  
Synthesis And Processing ◽  
Cylindrical Samples

A process for synthesis of fine zirconium titanate powders by chemical route is described. Zirconium/titanium molar ratio was varied from 0.67 to 1.5 and the powders produced were analyzed. The precipitation process comprises the mixture of zirconium and titanium metal salt solutions to ammonium hydroxide solution, followed by washing of the precipitate, calcination and grinding to result in zirconium titanate. The ceramic powder is then uniaxially pressed as cylindrical samples and sintered at 1400°C for 5 hours. The microstructure of fractured and thermally etched ceramic was observed by scanning electron microscopy, and crystal phase identifications were done by X-ray diffraction. At least two different zirconium titanate phases, ZrTiO4 and Zr5Ti7O24, were identified. Ceramic hardness was measured by Vickers indentation.

Sign in / Sign up

Export Citation Format

Share Document